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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2005 1
2010 3
2011 1
2012 4
2013 2
2014 11
2015 5
2016 2
2017 4
2018 7
2019 16
2020 18
2021 9
2022 8
2023 6

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90 results

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Page 1
Rewiring of the ubiquitinated proteome determines ageing in C. elegans.
Koyuncu S, Loureiro R, Lee HJ, Wagle P, Krueger M, Vilchez D. Koyuncu S, et al. Among authors: wagle p. Nature. 2021 Aug;596(7871):285-290. doi: 10.1038/s41586-021-03781-z. Epub 2021 Jul 28. Nature. 2021. PMID: 34321666 Free PMC article.
Because ubiquitination can tag proteins for recognition by the proteasome(3), a fundamental question is whether deficits in targeted degradation influence longevity. ...Lowering the levels of age-dysregulated proteasome targets prolongs longevity, whereas preventing their …
Because ubiquitination can tag proteins for recognition by the proteasome(3), a fundamental question is whether deficits in targeted …
Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L.
Wani GA, Sprenger HG, Ndoci K, Chandragiri S, Acton RJ, Schatton D, Kochan SMV, Sakthivelu V, Jevtic M, Seeger JM, Müller S, Giavalisco P, Rugarli EI, Motori E, Langer T, Bergami M. Wani GA, et al. Among authors: muller s. Cell Rep. 2022 Feb 15;38(7):110370. doi: 10.1016/j.celrep.2022.110370. Cell Rep. 2022. PMID: 35172139 Free article.
Mitochondria-Endoplasmic Reticulum Contacts in Reactive Astrocytes Promote Vascular Remodeling.
Gӧbel J, Engelhardt E, Pelzer P, Sakthivelu V, Jahn HM, Jevtic M, Folz-Donahue K, Kukat C, Schauss A, Frese CK, Giavalisco P, Ghanem A, Conzelmann KK, Motori E, Bergami M. Gӧbel J, et al. Among authors: frese ck. Cell Metab. 2020 Apr 7;31(4):791-808.e8. doi: 10.1016/j.cmet.2020.03.005. Epub 2020 Mar 26. Cell Metab. 2020. PMID: 32220306 Free PMC article.
Integrated imaging approaches revealed that this mitochondrial clustering is part of an adaptive response regulated by fusion dynamics. Astrocyte-specific conditional deletion of Mitofusin 2 (Mfn2) suppressed perivascular mitochondrial clustering and disrupted mitochondria …
Integrated imaging approaches revealed that this mitochondrial clustering is part of an adaptive response regulated by fusion dynamics. Astr …
Plasma-sensitive Escherichia coli mutants reveal plasma resistance mechanisms.
Krewing M, Jarzina F, Dirks T, Schubert B, Benedikt J, Lackmann JW, Bandow JE. Krewing M, et al. Among authors: lackmann jw. J R Soc Interface. 2019 Mar 29;16(152):20180846. doi: 10.1098/rsif.2018.0846. J R Soc Interface. 2019. PMID: 30913981 Free PMC article.
To identify plasma-derived components that the 87 genes confer resistance against, mutants were tested for hypersensitivity against individual stressors (hydrogen peroxide, superoxide, hydroxyl radicals, ozone, HOCl, peroxynitrite, NO, nitrite, nitrate, HNO(3), acid stress …
To identify plasma-derived components that the 87 genes confer resistance against, mutants were tested for hypersensitivity against individu …
A systematic analysis of diet-induced nephroprotection reveals overlapping changes in cysteine catabolism.
Koehler FC, Fu CY, Späth MR, Hoyer-Allo KJR, Bohl K, Göbel H, Lackmann JW, Grundmann F, Osterholt T, Gloistein C, Steiner JD, Antebi A, Benzing T, Schermer B, Schwarz G, Burst V, Müller RU. Koehler FC, et al. Among authors: lackmann jw. Transl Res. 2022 Jun;244:32-46. doi: 10.1016/j.trsl.2022.02.003. Epub 2022 Feb 18. Transl Res. 2022. PMID: 35189406
Interestingly, these approaches show overlapping changes in oxidative and hydrogen sulfide (H(2)S)-dependent cysteine catabolism as a potential common mechanism of organ protection....
Interestingly, these approaches show overlapping changes in oxidative and hydrogen sulfide (H(2)S)-dependent cysteine catabolism as a …
JAK/STAT-Activating Genomic Alterations Are a Hallmark of T-PLL.
Wahnschaffe L, Braun T, Timonen S, Giri AK, Schrader A, Wagle P, Almusa H, Johansson P, Bellanger D, López C, Haferlach C, Stern MH, Dürig J, Siebert R, Mustjoki S, Aittokallio T, Herling M. Wahnschaffe L, et al. Among authors: wagle p. Cancers (Basel). 2019 Nov 21;11(12):1833. doi: 10.3390/cancers11121833. Cancers (Basel). 2019. PMID: 31766351 Free PMC article.
We eliminated overlapping cases and determined a cumulative rate of 62.1% of cases with mutated JAK or STAT genes. Most frequently, JAK1 (6.3%), JAK3 (36.4%), and STAT5B (18.8%) carried somatic single-nucleotide variants (SNVs), with missense mutations in the SH2 or …
We eliminated overlapping cases and determined a cumulative rate of 62.1% of cases with mutated JAK or STAT genes. Most frequently, JAK1 ( …
90 results