Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2021 1
2022 23
2023 28
2024 27
2025 42
2026 7

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

114 results

Results by year

Filters applied: . Clear all
Page 1
Deciphering the tumor immune microenvironment: single-cell and spatial transcriptomic insights into cervical cancer fibroblasts.
Lin Z, Zhou Y, Liu Z, Nie W, Cao H, Li S, Li X, Zhu L, Lin G, Ding Y, Jiang Y, Gu Z, Xu L, Zhao Z, Cai H. Lin Z, et al. J Exp Clin Cancer Res. 2025 Jul 5;44(1):194. doi: 10.1186/s13046-025-03432-5. J Exp Clin Cancer Res. 2025. PMID: 40616092 Free PMC article.
RESULTS: Six distinct fibroblast subtypes were identified, including the C0 MYH11 + fibroblasts, which exhibited unique roles in stemness maintenance, metabolic activity, and immune regulation. ...Fibroblasts show spatially regulated heterogeneity, with activation markers …
RESULTS: Six distinct fibroblast subtypes were identified, including the C0 MYH11 + fibroblasts, which exhibited unique roles in stem …
Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia.
Cheng WY, Li JF, Zhu YM, Lin XJ, Wen LJ, Zhang F, Zhang YL, Zhao M, Fang H, Wang SY, Lin XJ, Qiao N, Yin W, Zhang JN, Dai YT, Jiang L, Sun XJ, Xu Y, Zhang TT, Chen SN, Zhu HH, Chen Z, Jin J, Wu DP, Shen Y, Chen SJ. Cheng WY, et al. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2211429119. doi: 10.1073/pnas.2211429119. Epub 2022 Nov 28. Proc Natl Acad Sci U S A. 2022. PMID: 36442087 Free PMC article.
Apart from four well-known low-risk subgroups including PML::RARA (G1), CBFB::MYH11 (G2), RUNX1::RUNX1T1 (G3), biallelic CEBPA mutations or -like (G4), four meta-subgroups with poor outcomes were recognized. ...
Apart from four well-known low-risk subgroups including PML::RARA (G1), CBFB::MYH11 (G2), RUNX1::RUNX1T1 (G3), biallelic CEBPA mutati …
Single-cell RNA sequencing reveals the vascular smooth muscle cell phenotypic landscape in aortic aneurysm.
Cao G, Xuan X, Li Y, Hu J, Zhang R, Jin H, Dong H. Cao G, et al. Cell Commun Signal. 2023 May 15;21(1):113. doi: 10.1186/s12964-023-01120-5. Cell Commun Signal. 2023. PMID: 37189183 Free PMC article.
VSMCs were identified according to the expression levels of ACTA2 and MYH11. VSMCs clustering was determined by the R package 'Seurat'. Cell annotation was determined by the R package 'singleR' and background knowledge of VSMCs phenotypic switching. ...
VSMCs were identified according to the expression levels of ACTA2 and MYH11. VSMCs clustering was determined by the R package 'Seurat …
Single-cell transcriptome analysis reveals CD34 as a marker of human sinoatrial node pacemaker cardiomyocytes.
Lim AA, Pouyabahar D, Ashraf M, Huang K, Lohbihler M, Murareanu BM, Chang ML, Kwan M, Alibhai FJ, Tran T, Mazine A, Laflamme MA, Bader GD, Laksman Z, Protze S. Lim AA, et al. Nat Commun. 2024 Nov 27;15(1):10206. doi: 10.1038/s41467-024-54337-4. Nat Commun. 2024. PMID: 39604360 Free PMC article.
Our study identifies a host of sinoatrial node pacemaker markers including MYH11, BMP4, and the cell surface antigen CD34. We demonstrate that sorting for CD34(+) cells from stem cell differentiation cultures enriches for sinoatrial node cells exhibiting a functional pacem …
Our study identifies a host of sinoatrial node pacemaker markers including MYH11, BMP4, and the cell surface antigen CD34. We demonst …
Expanding the phenotypic spectrum of Chromosome 16p13.11 microduplication: A multicentric analysis of 206 patients.
Hamad A, Sherlaw-Sturrock CA, Glover K, Salmon R, Low K, Nair R, Sansbury FH, Rawlins L, Carmichael J, Horton R, Wedderburn S, Edgerley K, Irving R, Callaghan M, Mercer C, McGowan R, Robert L, Titheradge H, Naik S. Hamad A, et al. Eur J Med Genet. 2023 Apr;66(4):104714. doi: 10.1016/j.ejmg.2023.104714. Epub 2023 Jan 29. Eur J Med Genet. 2023. PMID: 36724812
Other clinical features, such as cardiac abnormalities have also been reported. The duplicated region contains the MYH11 gene, which encodes the protein myosin-11 and is a component of the myosin heavy chain in smooth muscle. ...
Other clinical features, such as cardiac abnormalities have also been reported. The duplicated region contains the MYH11 gene, which …
Proteomic subtypes enrich current acute myeloid leukemia nomenclature and reflect intrinsic pathogenesis alongside aging.
Cheng WY, Yi X, Wang ZY, Li JF, Zhang JY, Zhang RH, Zhang QQ, Weng XQ, Huang T, Zhu YM, Wang C, Yin W, Zhang JN, Wu HY, Li JM, Zhu HM, Chen L, Wang WF, Dai YT, Gao CX, Liu X, Wang S, Wang SY, Jiao B, Chen Z, Fang H, Yin T, Shen Y, Chen SJ. Cheng WY, et al. Blood. 2025 Nov 27;146(22):2681-2695. doi: 10.1182/blood.2024027692. Blood. 2025. PMID: 40829168 Free PMC article.
Through similarity network fusion clustering, we established 8 proteomic subtypes with distinct clinical and molecular properties, including S1 (CEBPA mutations), S3 (myelodysplasia-related AML), S4 (PML::RARA), S5 (NPM1 mutations), S6 (PML::RARA and RUNX1::RUNX1T1), S8 (CBFB:: …
Through similarity network fusion clustering, we established 8 proteomic subtypes with distinct clinical and molecular properties, including …
Targeted next-generation sequencing reveals the genetic mechanism of Chinese Marfan syndrome cohort with ocular manifestation.
Han D, Wang Z, Chen X, Liu Z, Yang Z, Chen Y, Tian P, Li J, Wang Z. Han D, et al. Mol Genet Genomic Med. 2024 Jul;12(7):e2482. doi: 10.1002/mgg3.2482. Mol Genet Genomic Med. 2024. PMID: 38958168 Free PMC article.
Most cases are due to heterozygous mutations in the fibrillin-1 gene (FBN1). Other associated genes include LTBP2, MYH11, MYLK, and SLC2A10. There is significant clinical overlap between MFS and other Marfan-like disorders. ...
Most cases are due to heterozygous mutations in the fibrillin-1 gene (FBN1). Other associated genes include LTBP2, MYH11, MYLK, and S …
A multi-omics pipeline integrating machine learning and spatial-cellular analysis identifies SASH1 as a prognostic biomarker and therapeutic target in head and neck squamous cell carcinoma.
Dai Z, Shan X, Kang Y, Chen Y, Feng Q, Cai Z, Xie S. Dai Z, et al. Int J Surg. 2025 Dec 1;111(12):9178-9195. doi: 10.1097/JS9.0000000000003647. Epub 2025 Oct 16. Int J Surg. 2025. PMID: 41099090 Free PMC article.
RESULTS: An integrated analysis of bulk transcriptomic data identified 159 consensus DEGs, from which four core genes (COL1A1, EMP1, MYH11, SASH1) were robustly selected by all four machine learning algorithms. Multi-omics validation revealed that SASH1 was specifically do …
RESULTS: An integrated analysis of bulk transcriptomic data identified 159 consensus DEGs, from which four core genes (COL1A1, EMP1, MYH1 …
Regulation of Ptbp1-controlled alternative splicing of pyruvate kinase muscle by liver kinase B1 governs vascular smooth muscle cell plasticity in vivo.
Cai Z, Satyanarayana G, Song P, Zhao F, You S, Liu Z, Mu J, Ding Y, He B, Zou MH. Cai Z, et al. Cardiovasc Res. 2024 Nov 25;120(14):1780-1793. doi: 10.1093/cvr/cvae187. Cardiovasc Res. 2024. PMID: 39189621 Free PMC article.
METHODS AND RESULTS: We found that smooth muscle cell-specific deletion of Lkb1 in tamoxifen-inducible Lkb1flox/flox;Myh11-Cre/ERT2 mice spontaneously and progressively induced aortic/arterial dilation, aneurysm, rupture, and premature death. ...Treatment with PKM2 activat …
METHODS AND RESULTS: We found that smooth muscle cell-specific deletion of Lkb1 in tamoxifen-inducible Lkb1flox/flox;Myh11-Cre/ERT2 m …
Etiology of oncogenic fusions in 5,190 childhood cancers and its clinical and therapeutic implication.
Liu Y, Klein J, Bajpai R, Dong L, Tran Q, Kolekar P, Smith JL, Ries RE, Huang BJ, Wang YC, Alonzo TA, Tian L, Mulder HL, Shaw TI, Ma J, Walsh MP, Song G, Westover T, Autry RJ, Gout AM, Wheeler DA, Wan S, Wu G, Yang JJ, Evans WE, Loh M, Easton J, Zhang J, Klco JM, Meshinchi S, Brown PA, Pruett-Miller SM, Ma X. Liu Y, et al. Nat Commun. 2023 Apr 5;14(1):1739. doi: 10.1038/s41467-023-37438-4. Nat Commun. 2023. PMID: 37019972 Free PMC article.
Our mathematical modeling reveals a strong link between differential selection pressure and clinical outcome in CBFB-MYH11. We discover 4 oncogenic fusions, including RUNX1-RUNX1T1, TCF3-PBX1, CBFA2T3-GLIS2, and KMT2A-AFDN, with promoter-hijacking-like features that may of …
Our mathematical modeling reveals a strong link between differential selection pressure and clinical outcome in CBFB-MYH11. We discov …
114 results