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NSD1: A Lysine Methyltransferase between Developmental Disorders and Cancer.
Tauchmann S, Schwaller J. Tauchmann S, et al. Life (Basel). 2021 Aug 25;11(9):877. doi: 10.3390/life11090877. Life (Basel). 2021. PMID: 34575025 Free PMC article. Review.
Recurrent epigenomic alterations associated with multiple human pathologies have increased the interest in the nuclear receptor binding SET domain protein 1 (NSD1) lysine methyltransferase. Here, we review the current knowledge about the biochemistry, cellular function and …
Recurrent epigenomic alterations associated with multiple human pathologies have increased the interest in the nuclear receptor binding SET …
Prognostic importance of NUP98-rearrangements in acute myeloid leukemia: A systematic review and meta-analysis.
Sheikhi M, Siyadat P, Rostami M, Sadeghian MH, Zahiri E, Ghorbani M, Ayatollahi H, Ayatollahi A, Hemmatan Attarbashi R, Khoshnegah Z. Sheikhi M, et al. Caspian J Intern Med. 2024 Aug 30;15(4):579-588. doi: 10.22088/cjim.15.4.579. eCollection 2024 Fall. Caspian J Intern Med. 2024. PMID: 39359452 Free PMC article. Review.
SECTION TITLE: Our Results : analyses for NUP98-NSD1 indicated that this fusion could significantly impact the outcome of patients with AML (pooled HR: 2.84; 95% CI: 2.49-3.24, P=0.000). ...A subgroup analysis also showed that the NUP98-NSD1 and FLT3-I …
SECTION TITLE: Our Results : analyses for NUP98-NSD1 indicated that this fusion could significantly impact the outcome of pati …
Acute Myeloid Leukemia With Myelodysplasia-Related Changes.
Vardiman J, Reichard K. Vardiman J, et al. Am J Clin Pathol. 2015 Jul;144(1):29-43. doi: 10.1309/AJCP58RSMFRHLHHH. Am J Clin Pathol. 2015. PMID: 26071460 Review.
RESULTS: Session 3 of the workshop cases displayed heterogeneity as expected within AML-MRC, yet several cases suggested that recently recognized entities may exist within this category, such as familial MDS/AML predisposition syndromes and rare cases of high-risk AML associated …
RESULTS: Session 3 of the workshop cases displayed heterogeneity as expected within AML-MRC, yet several cases suggested that recently recog …
Acute erythroid leukemia is enriched in NUP98 fusions: a report from the Children's Oncology Group.
Chisholm KM, Heerema-McKenney AE, Choi JK, Smith J, Ries RE, Hirsch BA, Raimondi SC, Alonzo TA, Wang YC, Aplenc R, Sung L, Gamis AS, Meshinchi S, Kahwash SB. Chisholm KM, et al. Blood Adv. 2020 Dec 8;4(23):6000-6008. doi: 10.1182/bloodadvances.2020002712. Blood Adv. 2020. PMID: 33284945 Free PMC article.
In this pediatric AEL study, we evaluated morphologic, immunophenotypic, cytogenetic, molecular, and clinical data of 24 (1.2%) cases from all cases undergoing central pathology review in Children's Oncology Group trials AAML0531 and AAML1031. Of 24 cases, 5 had a pure ery …
In this pediatric AEL study, we evaluated morphologic, immunophenotypic, cytogenetic, molecular, and clinical data of 24 (1.2%) cases from a …