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Updates on Paget's Disease of Bone.
Choi YJ, Sohn YB, Chung YS. Choi YJ, et al. Endocrinol Metab (Seoul). 2022 Oct;37(5):732-743. doi: 10.3803/EnM.2022.1575. Epub 2022 Oct 25. Endocrinol Metab (Seoul). 2022. PMID: 36327984 Free PMC article.
Paget's disease of the bone is a prevalent bone disease characterized by disorganized bone remodeling; however, it is comparatively uncommon in East Asian countries, including China, Japan, and Korea. ...Moreover, biochemical monitoring i …
Paget's disease of the bone is a prevalent bone disease characterized by disorganized bone remodel …
Paget's disease of bone: 1877-2023. Etiology, and management of a disease on epidemiologic transition.
Corral Gudino L. Corral Gudino L. Med Clin (Barc). 2023 Sep 8;161(5):207-216. doi: 10.1016/j.medcli.2023.05.005. Epub 2023 May 30. Med Clin (Barc). 2023. PMID: 37263846 Free article. Review. English, Spanish.
Paget's disease of bone is characterized by the alteration, in one or several bone locations, of the equilibrium between bone formation and bone resorption. This imbalance results in a disorganized, widened bone, in many cas …
Paget's disease of bone is characterized by the alteration, in one or several bone locations, of the equi …
Diagnosis and treatment of Paget's disease of bone: position paper from the Italian Society of Osteoporosis, Mineral Metabolism and Skeletal Diseases (SIOMMMS).
Rendina D, Falchetti A, Diacinti D, Bertoldo F, Merlotti D, Giannini S, Cianferotti L, Girasole G, Di Monaco M, Gonnelli S, Malavolta N, Minisola S, Vescini F, Rossini M, Frediani B, Chiodini I, Asciutti F, Gennari L. Rendina D, et al. J Endocrinol Invest. 2024 Jun;47(6):1335-1360. doi: 10.1007/s40618-024-02318-1. Epub 2024 Mar 15. J Endocrinol Invest. 2024. PMID: 38488978 Free PMC article. Review.
INTRODUCTION: Paget's disease of bone is a focal skeletal disorder causing bone deformities and impairing bone quality. ...However, limited information is available from randomized controlled trials on the prevention of disease complicati …
INTRODUCTION: Paget's disease of bone is a focal skeletal disorder causing bone deformities and impairing …
The evaluation and treatment of Paget's disease of bone.
Singer FR. Singer FR. Best Pract Res Clin Rheumatol. 2020 Jun;34(3):101506. doi: 10.1016/j.berh.2020.101506. Epub 2020 Apr 11. Best Pract Res Clin Rheumatol. 2020. PMID: 32291204 Review.
Paget's disease of bone is a localized skeletal disorder, which is more common in England and in countries to which the English migrated. ...Patients may be asymptomatic and may be diagnosed accidently as a consequence of an elevated serum alkaline pho …
Paget's disease of bone is a localized skeletal disorder, which is more common in England and in countries to wh …
Genetic Determinants of Paget's Disease of Bone.
Makaram NS, Ralston SH. Makaram NS, et al. Curr Osteoporos Rep. 2021 Jun;19(3):327-337. doi: 10.1007/s11914-021-00676-w. Epub 2021 May 14. Curr Osteoporos Rep. 2021. PMID: 33988819 Free PMC article. Review.
PURPOSE OF REVIEW: To provide an overview of the role of genes and loci that predispose to Paget's disease of bone and related disorders. RECENT FINDINGS: Studies over the past ten years have seen major advances in knowledge on the role of genetic …
PURPOSE OF REVIEW: To provide an overview of the role of genes and loci that predispose to Paget's disease of bone …
Adult Paget's disease of bone.
Tuck SP, Walker J. Tuck SP, et al. Clin Med (Lond). 2020 Nov;20(6):568-571. doi: 10.7861/clinmed.20.6.page. Clin Med (Lond). 2020. PMID: 33199322 Free PMC article.
Adult Paget's disease of bone is the second commonest metabolic bone condition after osteoporosis. ...This leads to expanded bone of poor quality possessing both sclerotic and lytic areas. Paget's disease of bone …
Adult Paget's disease of bone is the second commonest metabolic bone condition after osteoporosis. ...Thi …
VCP activator reverses nuclear proteostasis defects and enhances TDP-43 aggregate clearance in multisystem proteinopathy models.
Phan JM, Creekmore BC, Nguyen AT, Bershadskaya DD, Darwich NF, Mann CN, Lee EB. Phan JM, et al. J Clin Invest. 2024 May 23;134(14):e169039. doi: 10.1172/JCI169039. J Clin Invest. 2024. PMID: 38787785 Free PMC article.
Pathogenic variants in valosin-containing protein (VCP) cause multisystem proteinopathy (MSP), a disease characterized by multiple clinical phenotypes including inclusion body myopathy, Paget's disease of the bone, and frontotemporal dementia (FTD). Ho …
Pathogenic variants in valosin-containing protein (VCP) cause multisystem proteinopathy (MSP), a disease characterized by multiple clinical …
Where is bone science taking us?
Langdahl BL, Uitterlinden AG, Ralston SH. Langdahl BL, et al. Best Pract Res Clin Rheumatol. 2022 Sep;36(3):101791. doi: 10.1016/j.berh.2022.101791. Epub 2022 Nov 3. Best Pract Res Clin Rheumatol. 2022. PMID: 36336607 Free article. Review.
Bone science has over the last decades unraveled many important pathways in bone and mineral metabolism and the interplay between genetic factors and the environment. ...Huge advances have been made in identifying the genes that cause rare bone disease …
Bone science has over the last decades unraveled many important pathways in bone and mineral metabolism and the interplay betw …
VCP-related myopathy: a case series and a review of literature.
Iannibelli E, Gibertini S, Cheli M, Blasevich F, Cavaliere A, Riolo G, Ruggieri A, Maggi L. Iannibelli E, et al. Acta Myol. 2023 Mar 31;42(1):2-13. doi: 10.36185/2532-1900-244. eCollection 2023. Acta Myol. 2023. PMID: 37091525 Free PMC article. Review.
Frontotemporal dementia (FTD), inclusion body myopathy, and Paget's disease of the bone (PDB) are all caused by dominant missense mutations in the VCP gene, which interfere with these mechanisms and cause a multisystem proteinopathy. We describe …
Frontotemporal dementia (FTD), inclusion body myopathy, and Paget's disease of the bone (PDB) are all caused by …
68 results