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The Roles of PTEN in Melanoma Suppression.
Parkman GL, Xu X, Holmen SL, Karreth FA. Parkman GL, et al. Pigment Cell Melanoma Res. 2025 Sep;38(5):e70054. doi: 10.1111/pcmr.70054. Pigment Cell Melanoma Res. 2025. PMID: 40976930 Free PMC article. Review.
Effects of alpelisib treatment on murine Pten-deficient lipomas.
Merz LM, Winter K, Richter S, Kallendrusch S, Horn A, Grunewald S, Klöting N, Krause K, Kiess W, Le Duc D, Garten A. Merz LM, et al. Adipocyte. 2025 Dec;14(1):2468275. doi: 10.1080/21623945.2025.2468275. Epub 2025 Feb 17. Adipocyte. 2025. PMID: 39962643 Free PMC article.
The risk of a second primary cancer in PTEN Hamartoma Tumor Syndrome (PHTS).
Hendricks LAJ, Verbeek KCJ, Schuurs-Hoeijmakers JHM, de Jong MM, Links TP, Brems H, Aerden M, Brunet J, Lleuger-Pujol R, Hüneburg R, Aretz S, Colas C, Villy MC, Woodward ER, Evans DG, Bosch DGM, Donze SH, Foretová L, Blatnik A, Leter EM, Tischkowitz M, Jahn A, de Putter R, Dupont J, Briskemyr S, Steinke-Lange V, Baldassarri M, Anastasiadou VC, Irmejs A, Oliveira C, van der Post RS, Mensenkamp AR, Tesi B, Mu N, Benusiglio PR, Gerasimenko A, Innella G, Turchetti D, Houdayer C, Branchaud M, Høberg Vetti H, Tveit Haavind M, Balmaña J, Torres M, Genuardi M, Panfili A, Jørgensen K, Mæhle L, Hoogerbrugge N, Vos JR. Hendricks LAJ, et al. Genet Med. 2025 Oct;27(10):101467. doi: 10.1016/j.gim.2025.101467. Epub 2025 May 24. Genet Med. 2025. PMID: 40433764 Free article.
USP10/GSK3beta-mediated inhibition of PTEN drives resistance to PI3K inhibitors in breast cancer.
Kumari N, Wright SC, Witham CM, Monserrat L, Palafox M, Richard JL, Costa C, Elkabets M, Agostino M, Klemm T, Eccles M, Garnham A, Wu T, Nilsson JA, Walz N, Venugopal V, Cerra A, Vasilevski N, Bridgeman S, Bassi S, Saei A, Helal M, Neundorf P, Riedel A, Rosenfeldt M, Gill J, Pahor N, Hartmann O, Chung J, Sidhu SS, Moderau N, Jha S, Rodon J, Diefenbacher ME, Komander D, Serra V, Eichhorn PJA. Kumari N, et al. J Clin Invest. 2025 Sep 23;135(22):e180927. doi: 10.1172/JCI180927. eCollection 2025 Nov 17. J Clin Invest. 2025. PMID: 40991650 Free PMC article.
96 results