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2003 1
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Page 1
Stress biology: Complexity and multifariousness in health and disease.
Mayer MP, Blair L, Blatch GL, Borges TJ, Chadli A, Chiosis G, de Thonel A, Dinkova-Kostova A, Ecroyd H, Edkins AL, Eguchi T, Fleshner M, Foley KP, Fragkostefanakis S, Gestwicki J, Goloubinoff P, Heritz JA, Heske CM, Hibshman JD, Joutsen J, Li W, Lynes M, Mendillo ML, Mivechi N, Mokoena F, Okusha Y, Prahlad V, Repasky E, Sannino S, Scalia F, Shalgi R, Sistonen L, Sontag E, van Oosten-Hawle P, Vihervaara A, Wickramaratne A, Wang SXY, Zininga T. Mayer MP, et al. Among authors: prahlad v. Cell Stress Chaperones. 2024 Feb;29(1):143-157. doi: 10.1016/j.cstres.2024.01.006. Epub 2024 Feb 3. Cell Stress Chaperones. 2024. PMID: 38311120 Free PMC article.
To counteract an imbalance in cellular homeostasis transcriptional programs evolved, called the heat shock response, unfolded protein response, and integrated stress response, that act cell-autonomously in most cells but in multicellular organisms are subject …
To counteract an imbalance in cellular homeostasis transcriptional programs evolved, called the heat shock response, unfolded protein respon …
Editorial: A new chapter for Cell Stress and Chaperones.
Bourboulia D, Blair LJ, Clark MS, Edkins AL, Hightower LE, Mollapour M, Prahlad V, Repasky EA, Truebano M, Truman AW, Truttmann MC, van Oosten-Hawle P, Woodford MR. Bourboulia D, et al. Among authors: prahlad v. Cell Stress Chaperones. 2024 Feb;29(1):113-115. doi: 10.1016/j.cstres.2024.01.007. Epub 2024 Feb 1. Cell Stress Chaperones. 2024. PMID: 38309687 Free PMC article. No abstract available.
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R… See abstract for full author list ➔ Klionsky DJ, et al. Among authors: prahlad v. Autophagy. 2021 Jan;17(1):1-382. doi: 10.1080/15548627.2020.1797280. Epub 2021 Feb 8. Autophagy. 2021. PMID: 33634751 Free PMC article.
Neuromodulators: an essential part of survival.
Alcedo J, Prahlad V. Alcedo J, et al. Among authors: prahlad v. J Neurogenet. 2020 Sep-Dec;34(3-4):475-481. doi: 10.1080/01677063.2020.1839066. Epub 2020 Nov 10. J Neurogenet. 2020. PMID: 33170042 Free PMC article. Review.
In this perspective, we highlight a collection of articles in this issue that describe how neuromodulators optimize C. elegans survival....
In this perspective, we highlight a collection of articles in this issue that describe how neuromodulators optimize C. elegans …
Neuronal IL-17 controls Caenorhabditis elegans developmental diapause through CEP-1/p53.
Godthi A, Min S, Das S, Cruz-Corchado J, Deonarine A, Misel-Wuchter K, Issuree PD, Prahlad V. Godthi A, et al. Among authors: prahlad v. Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2315248121. doi: 10.1073/pnas.2315248121. Epub 2024 Mar 14. Proc Natl Acad Sci U S A. 2024. PMID: 38483995 Free PMC article.
Here, we show that nutrient availability signaled by the neuronal cytokine, ILC-17.1, switches Caenorhabditis elegans development between reproductive growth and dormancy by controlling the activity of the tumor suppressor p53 ortholog, CEP-1. ...They also re …
Here, we show that nutrient availability signaled by the neuronal cytokine, ILC-17.1, switches Caenorhabditis elegans d …
Nature's gift to neuroscience.
Alcedo J, Jin Y, Portman DS, Prahlad V, Raizen D, Rapti G, Xu XZS, Zhang Y, Wu CF. Alcedo J, et al. Among authors: prahlad v. J Neurogenet. 2020 Sep-Dec;34(3-4):223-224. doi: 10.1080/01677063.2020.1841760. J Neurogenet. 2020. PMID: 33446019 Free PMC article. No abstract available.
The discovery and consequences of the central role of the nervous system in the control of protein homeostasis.
Prahlad V. Prahlad V. J Neurogenet. 2020 Sep-Dec;34(3-4):489-499. doi: 10.1080/01677063.2020.1771333. Epub 2020 Jun 12. J Neurogenet. 2020. PMID: 32527175 Free PMC article. Review.
Recent studies that exploit the powerful ability to genetically manipulate specific neurons in C. elegans have shown that cells within this metazoan lose their autonomy over this fundamental survival mechanism. ...PRELUDE: Whether the detailed examinat …
Recent studies that exploit the powerful ability to genetically manipulate specific neurons in C. elegans have shown th …
Integrating the stress response: lessons for neurodegenerative diseases from C. elegans.
Prahlad V, Morimoto RI. Prahlad V, et al. Trends Cell Biol. 2009 Feb;19(2):52-61. doi: 10.1016/j.tcb.2008.11.002. Epub 2008 Dec 26. Trends Cell Biol. 2009. PMID: 19112021 Free PMC article. Review.
All cells possess surveillance and homeostatic mechanisms to adjust protein biogenesis to the demands of growth, differentiation, ageing and environmental stress. ...Although the regulation of stress responses, such as the heat-shock response, and of proteost …
All cells possess surveillance and homeostatic mechanisms to adjust protein biogenesis to the demands of growth, differentiation, age …
The stress of protein misfolding: from single cells to multicellular organisms.
Gidalevitz T, Prahlad V, Morimoto RI. Gidalevitz T, et al. Among authors: prahlad v. Cold Spring Harb Perspect Biol. 2011 Jun 1;3(6):a009704. doi: 10.1101/cshperspect.a009704. Cold Spring Harb Perspect Biol. 2011. PMID: 21536706 Free PMC article. Review.
Here, we will address how protein homeostasis (proteostasis) is achieved at the level of the cell and organism, and how the threshold of the stress response is set to detect and combat protein misfolding. ...This is achieved by hierarchical regulation of heat shock …
Here, we will address how protein homeostasis (proteostasis) is achieved at the level of the cell and organism, and how the threshold …
Chromatin and epigenetics in aging biology.
Greer EL, Lee SS, Prahlad V. Greer EL, et al. Among authors: prahlad v. Genetics. 2025 May 8;230(1):iyaf055. doi: 10.1093/genetics/iyaf055. Genetics. 2025. PMID: 40202900 Review.
This book chapter will focus on modifications to chromatin itself, how chromatin modifications are regulated, and how these modifications are deciphered by the cell to impact aging. In this chapter, we will review how chromatin modifications change with age, examine how ch …
This book chapter will focus on modifications to chromatin itself, how chromatin modifications are regulated, and how these modifications ar …
29 results