Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.


The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page


My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2005 1
2007 2
2008 1
2009 1
2010 1
2011 1
2012 2
2013 2
2014 2
2015 4
2016 3
2017 5
2018 5
2019 8
2020 2
2021 5
2022 5
2023 4

Text availability

Article attribute

Article type

Publication date

Search Results

47 results

Results by year

Filters applied: . Clear all
Page 1
Comparing DRD2 Promoter Methylation Between Blood and Brain in Alcohol Dependence.
Arfmann W, Achenbach J, Meyer-Bockenkamp F, Proskynitopoulos PJ, Groh A, Muschler MAN, Glahn A, Hagemeier L, Preuss V, Klintschar M, Frieling H, Rhein M. Arfmann W, et al. Among authors: rhein m. Alcohol Alcohol. 2023 Mar 10;58(2):216-223. doi: 10.1093/alcalc/agad005. Alcohol Alcohol. 2023. PMID: 36747480
Dysregulated Methylation Patterns in Exon IV of the Brain-Derived Neurotrophic Factor (BDNF) Gene in Nicotine Dependence and Changes in BDNF Plasma Levels During Smoking Cessation.
Abdelkhalek K, Rhein M, Deest M, Buchholz V, Bleich S, Lichtinghagen R, Vyssoki B, Frieling H, Muschler M, Proskynitopoulos PJ, Glahn A. Abdelkhalek K, et al. Among authors: rhein m. Front Psychiatry. 2022 Jun 28;13:897801. doi: 10.3389/fpsyt.2022.897801. eCollection 2022. Front Psychiatry. 2022. PMID: 35836661 Free PMC article.
Differences in the promoter methylation of atrial natriuretic peptide and vasopressin in alcohol use disorder. A longitudinal case-control-study during withdrawal therapy.
Proskynitopoulos PJ, Rhein M, Petersson LP, Sperling CH, Wöhler J, Deest M, Bleich S, Frieling H, Hillemacher T, Glahn A. Proskynitopoulos PJ, et al. Among authors: rhein m. Psychoneuroendocrinology. 2021 Nov;133:105387. doi: 10.1016/j.psyneuen.2021.105387. Epub 2021 Aug 8. Psychoneuroendocrinology. 2021. PMID: 34399149
Alcohol consumption alters Gdnf promoter methylation and expression in rats.
Maier HB, Neyazi M, Neyazi A, Hillemacher T, Pathak H, Rhein M, Bleich S, Goltseker K, Sadot-Sogrin Y, Even-Chen O, Frieling H, Barak S. Maier HB, et al. Among authors: rhein m. J Psychiatr Res. 2020 Feb;121:1-9. doi: 10.1016/j.jpsychires.2019.10.020. Epub 2019 Oct 31. J Psychiatr Res. 2020. PMID: 31710958
DNA-methylation of the dopamin receptor 2 gene is altered during alcohol withdrawal.
Hillemacher T, Rhein M, Burkert A, Heberlein A, Wilhelm J, Glahn A, Muschler MAN, Kahl KG, Kornhuber J, Bleich S, Frieling H. Hillemacher T, et al. Among authors: rhein m. Eur Neuropsychopharmacol. 2019 Nov;29(11):1250-1257. doi: 10.1016/j.euroneuro.2019.09.002. Epub 2019 Sep 14. Eur Neuropsychopharmacol. 2019. PMID: 31530416
Childhood traumatization is associated with differences in TRPA1 promoter methylation in female patients with multisomatoform disorder with pain as the leading bodily symptom.
Achenbach J, Rhein M, Gombert S, Meyer-Bockenkamp F, Buhck M, Eberhardt M, Leffler A, Frieling H, Karst M. Achenbach J, et al. Among authors: rhein m. Clin Epigenetics. 2019 Aug 28;11(1):126. doi: 10.1186/s13148-019-0731-0. Clin Epigenetics. 2019. PMID: 31455424 Free PMC article.
Desacylghrelin but not acylghrelin is reduced during smoking cessation.
Ardeshiripur M, Rhein M, Frieling H, Bleich S, Hillemacher T, Muschler M, Glahn A. Ardeshiripur M, et al. Among authors: rhein m. J Neural Transm (Vienna). 2018 Dec;125(12):1885-1889. doi: 10.1007/s00702-018-1930-0. Epub 2018 Sep 24. J Neural Transm (Vienna). 2018. PMID: 30251224
Epigenetic alterations of the POMC promoter in tobacco dependence.
Muschler M, Rhein M, Ritter A, Hillemacher T, Frieling H, Bleich S, Glahn A. Muschler M, et al. Among authors: rhein m. Eur Neuropsychopharmacol. 2018 Jul;28(7):875-879. doi: 10.1016/j.euroneuro.2018.05.004. Epub 2018 Jun 2. Eur Neuropsychopharmacol. 2018. PMID: 29871818
Epigenetic Effects of Intravenous Diacetylmorphine on the Methylation of POMC and NR3C1.
Groh A, Rhein M, Buchholz V, Burkert A, Huber CG, Lang UE, Borgwardt SJ, Heberlein A, Muschler MAN, Hillemacher T, Bleich S, Frieling H, Walter M. Groh A, et al. Among authors: rhein m. Neuropsychobiology. 2017;75(4):193-199. doi: 10.1159/000486973. Epub 2018 Mar 6. Neuropsychobiology. 2017. PMID: 29510398 Clinical Trial.
Impaired Regulation of ALDH2 Protein Expression Revealing a Yet Unknown Epigenetic Impact of rs886205 on Specific Methylation of a Negative Regulatory Promoter Region in Alcohol-Dependent Patients.
Haschemi Nassab M, Rhein M, Hagemeier L, Kaeser M, Muschler M, Glahn A, Pich A, Heberlein A, Kornhuber J, Bleich S, Frieling H, Hillemacher T. Haschemi Nassab M, et al. Among authors: rhein m. Eur Addict Res. 2016;22(2):59-69. doi: 10.1159/000381018. Epub 2015 Sep 5. Eur Addict Res. 2016. PMID: 26339786
Do changes in the BDNF promoter methylation indicate the risk of alcohol relapse?
Heberlein A, Büscher P, Schuster R, Kleimann A, Lichtinghagen R, Rhein M, Kornhuber J, Bleich S, Frieling H, Hillemacher T. Heberlein A, et al. Among authors: rhein m. Eur Neuropsychopharmacol. 2015 Nov;25(11):1892-7. doi: 10.1016/j.euroneuro.2015.08.018. Epub 2015 Sep 5. Eur Neuropsychopharmacol. 2015. PMID: 26404404
No association between the ALDH2 promoter polymorphism rs886205, alcohol dependence, and risky alcohol consumption in a German population.
Haschemi Nassab M, Rhein M, Heese P, Glahn A, Frieling H, Linnebank M, Bleich S, Kornhuber J, Heberlein A, Grallert H, Peters A, Rawal R, Strauch K, Hillemacher T. Haschemi Nassab M, et al. Among authors: rhein m. Psychiatr Genet. 2015 Feb;25(1):41-2. doi: 10.1097/YPG.0000000000000073. Psychiatr Genet. 2015. PMID: 25419637 Free article. No abstract available.
Alcohol-induced changes in methylation status of individual CpG sites, and serum levels of vasopressin and atrial natriuretic peptide in alcohol-dependent patients during detoxification treatment.
Glahn A, Riera Knorrenschild R, Rhein M, Haschemi Nassab M, Gröschl M, Heberlein A, Muschler M, Frieling H, Bleich S, Hillemacher T. Glahn A, et al. Among authors: rhein m. Eur Addict Res. 2014;20(3):143-50. doi: 10.1159/000357473. Epub 2013 Dec 13. Eur Addict Res. 2014. PMID: 24356727
High-affinity neurotrophin receptors and ligands promote leukemogenesis.
Li Z, Beutel G, Rhein M, Meyer J, Koenecke C, Neumann T, Yang M, Krauter J, von Neuhoff N, Heuser M, Diedrich H, Göhring G, Wilkens L, Schlegelberger B, Ganser A, Baum C. Li Z, et al. Among authors: rhein m. Blood. 2009 Feb 26;113(9):2028-37. doi: 10.1182/blood-2008-05-155200. Epub 2008 Dec 4. Blood. 2009. PMID: 19059881 Free PMC article.