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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 2
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2001 1
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2007 1
2008 1
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2011 5
2012 3
2013 3
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151 results

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Page 1
Rosacea: Pathogenesis and Therapeutic Correlates.
Geng RSQ, Bourkas AN, Mufti A, Sibbald RG. Geng RSQ, et al. J Cutan Med Surg. 2024 Mar-Apr;28(2):178-189. doi: 10.1177/12034754241229365. Epub 2024 Mar 7. J Cutan Med Surg. 2024. PMID: 38450615 Free PMC article. Review.
The pathogenesis of rosacea is likely multifactorial, involving genetic and environmental contributions. Current understanding suggests that pro-inflammatory pathways involving cathelicidins and inflammasome complexes are central to rosacea pathogenesis. ...
The pathogenesis of rosacea is likely multifactorial, involving genetic and environmental contributions. Current understanding sugges …
Bioinformatics and Network Pharmacology Identify the Therapeutic Role and Potential Mechanism of Melatonin in AD and Rosacea.
Zhang H, Zhang Y, Li Y, Wang Y, Yan S, Xu S, Deng Z, Yang X, Xie H, Li J. Zhang H, et al. Front Immunol. 2021 Nov 23;12:756550. doi: 10.3389/fimmu.2021.756550. eCollection 2021. Front Immunol. 2021. PMID: 34899707 Free PMC article.
Using the TF regulatory network analysis, 37 common TFs and target genes were identified as hub genes. They were used to predict the therapeutic drugs for rosacea and AD using the DGIdb/CMap database. ...
Using the TF regulatory network analysis, 37 common TFs and target genes were identified as hub genes. They were used to predi …
Signaling pathways and targeted therapy for rosacea.
Yang F, Wang L, Song D, Zhang L, Wang X, Du D, Jiang X. Yang F, et al. Front Immunol. 2024 Sep 16;15:1367994. doi: 10.3389/fimmu.2024.1367994. eCollection 2024. Front Immunol. 2024. PMID: 39351216 Free PMC article. Review.
Its pathogenesis involves a complex interplay of genetic, environmental, immune, microbial, and neurovascular factors. Recent studies have advanced our understanding of its molecular basis, focusing on toll-like receptor (TLR) 2 pathways, LL37 expression, mammalian target …
Its pathogenesis involves a complex interplay of genetic, environmental, immune, microbial, and neurovascular factors. Recent studies …
Single-cell transcriptomics reveals aberrant skin-resident cell populations and identifies fibroblasts as a determinant in rosacea.
Chen M, Yang L, Zhou P, Jin S, Wu Z, Tan Z, Xiao W, Xu S, Zhu Y, Wang M, Jian D, Liu F, Tang Y, Zhao Z, Huang Y, Shi W, Xie H, Nie Q, Wang B, Deng Z, Li J. Chen M, et al. Nat Commun. 2024 Oct 9;15(1):8737. doi: 10.1038/s41467-024-52946-7. Nat Commun. 2024. PMID: 39384741 Free PMC article.
Depletion of fibroblasts or knockdown of PTGDS, a gene specifically upregulated in fibroblasts, blocks rosacea development in mice. Our study provides a comprehensive understanding of the aberrant alterations of skin-resident cell populations and identifies fibroblasts as …
Depletion of fibroblasts or knockdown of PTGDS, a gene specifically upregulated in fibroblasts, blocks rosacea development in mice. O …
Probiotics and Diet in Rosacea: Current Evidence and Future Perspectives.
Manfredini M, Barbieri M, Milandri M, Longo C. Manfredini M, et al. Biomolecules. 2025 Mar 13;15(3):411. doi: 10.3390/biom15030411. Biomolecules. 2025. PMID: 40149947 Free PMC article. Review.
The pathophysiology of rosacea remains unclear, but the complex interplay between environmental and genetic factors may act as a trigger to an abnormal innate immune response associated with a multifaceted neurovascular reaction. ...
The pathophysiology of rosacea remains unclear, but the complex interplay between environmental and genetic factors may act as a trig …
Recent advances in understanding and managing rosacea.
Buddenkotte J, Steinhoff M. Buddenkotte J, et al. F1000Res. 2018 Dec 3;7:F1000 Faculty Rev-1885. doi: 10.12688/f1000research.16537.1. eCollection 2018. F1000Res. 2018. PMID: 30631431 Free PMC article. Review.
However, recent findings indicate that genetic and environmental components can trigger rosacea initiation and aggravation by dysregulation of the innate and adaptive immune system. ...
However, recent findings indicate that genetic and environmental components can trigger rosacea initiation and aggravation by dysregu …
Therapeutic strategies focusing on immune dysregulation and neuroinflammation in rosacea.
Tu KY, Jung CJ, Shih YH, Chang ALS. Tu KY, et al. Front Immunol. 2024 Jul 29;15:1403798. doi: 10.3389/fimmu.2024.1403798. eCollection 2024. Front Immunol. 2024. PMID: 39136023 Free PMC article. Review.
The development of rosacea is influenced by both external triggers and genetics, but the common pathophysiology is overactivation of the immune system. Here, we review the current data on proinflammatory cytokines and dysregulation of the neurovascular system as targetable …
The development of rosacea is influenced by both external triggers and genetics, but the common pathophysiology is overactivation of …
Ocular Rosacea: An Updated Review.
Mohamed-Noriega K, Loya-Garcia D, Vera-Duarte GR, Morales-Wong F, Ortiz-Morales G, Navas A, Graue-Hernandez EO, Ramirez-Miranda A. Mohamed-Noriega K, et al. Cornea. 2025 Apr 1;44(4):525-537. doi: 10.1097/ICO.0000000000003785. Epub 2025 Jan 14. Cornea. 2025. PMID: 39808113 Free PMC article. Review.
A multidisciplinary approach, including new therapeutic options, holds promise for improving patient care. Further research into the genetic and molecular basis of ocular rosacea may enable more personalized treatments....
A multidisciplinary approach, including new therapeutic options, holds promise for improving patient care. Further research into the gene …
Effect of combined probiotics and doxycycline therapy on the gut-skin axis in rosacea.
Yu J, Duan Y, Zhang M, Li Q, Cao M, Song W, Zhao F, Kwok L-Y, Zhang H, Li R, Sun Z. Yu J, et al. mSystems. 2024 Nov 19;9(11):e0120124. doi: 10.1128/msystems.01201-24. Epub 2024 Oct 30. mSystems. 2024. PMID: 39475254 Free PMC article. Clinical Trial.
These changes were associated with reduced facial sebum levels and a lower physician's global assessment score. Finally, fewer antibiotic resistance genes, particularly tetracycline resistance genes, were detected in the probiotic group compared with the control and …
These changes were associated with reduced facial sebum levels and a lower physician's global assessment score. Finally, fewer antibiotic re …
Rosacea and rhinophyma.
Tüzün Y, Wolf R, Kutlubay Z, Karakuş O, Engin B. Tüzün Y, et al. Clin Dermatol. 2014 Jan-Feb;32(1):35-46. doi: 10.1016/j.clindermatol.2013.05.024. Clin Dermatol. 2014. PMID: 24314376 Review.
The pathophysiology of rosacea is still poorly understood. Epidemiological studies indicate a genetic component, but a rosacea gene has not been detected yet. Recent molecular studies propose that an altered innate immune response is involved in the pathogenesis of …
The pathophysiology of rosacea is still poorly understood. Epidemiological studies indicate a genetic component, but a rosacea gen …
151 results