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32 results

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Page 1
Subretinal injection in the USH1CR31∗ pig model leads to chorioretinal atrophy that limits evaluation of efficacy of an AAV-mediated gene therapy.
Nyshchuk R, Klein J, Seitz IP, Peters T, Mai M, Ardan T, Drutovič S, Levinská Bohuslavová B, Juhás Š, Juhásová J, Tütüncü Y, Nemesh Y, Reifferscheid LM, DeMott KP, Klein JJ, Nagel-Wolfrum K, Klymiuk N, Winslow AR, Motlik J, Ellederova Z, Fischer MD, Wolfrum U. Nyshchuk R, et al. Among authors: seitz ip. Exp Eye Res. 2026 Jul 2;271:111151. doi: 10.1016/j.exer.2026.111151. Online ahead of print. Exp Eye Res. 2026. PMID: 42392489 Free article.
Deep-sequencing-guided library screening and profiling of AAV capsids in the primate retina.
Fouani Y, Blazevic D, Oti M, Becker R, Strobel B, Schönberger T, Stephan M, Wichert S, Reichel FF, Seitz IP, Korbmacher B, Achberger K, Roosz J, Loskill P, Maier U, Michelfelder S, Schön C. Fouani Y, et al. Among authors: seitz ip. Mol Ther Adv. 2026 May 22;34(3):201764. doi: 10.1016/j.omta.2026.201764. eCollection 2026 Sep 10. Mol Ther Adv. 2026. PMID: 42318137 Free PMC article.
[On the urgency of treating ophthalmic emergencies].
Seitz IP, Kelbsch C, Besch D, Gosheva M, Pleyer U, Tekeva-Rohrbach C, Fischer MD, Bartz-Schmidt KU, Rohrbach JM. Seitz IP, et al. Ophthalmologie. 2026 Mar;123(3):237-253. doi: 10.1007/s00347-026-02393-0. Epub 2026 Feb 25. Ophthalmologie. 2026. PMID: 41739160 Review. German.
Subretinal Injection Volume Correlates to Persistent Outer Retinal Thinning in the Pig Eye.
Seitz IP, Nyshchuk R, Ellederova Z, Ardan T, Juhasova J, Nemesh Y, Juhas S, Drutovic S, Süsskind D, Schnichels S, Motlik J, Klymiuk N, Wolfrum U, Post DeMott K, Klein JJ, Winslow A, Fischer MD. Seitz IP, et al. Invest Ophthalmol Vis Sci. 2025 Nov 3;66(14):27. doi: 10.1167/iovs.66.14.27. Invest Ophthalmol Vis Sci. 2025. PMID: 41230903 Free PMC article.
Safety and vision outcomes of subretinal gene supplementation therapy in PDE6A-associated retinitis pigmentosa: a non-randomised controlled trial.
Reichel FF, Fischer MD, Stingl K, Kuehlewein L, Seitz I, Peters T, Ziegler M, Wilhelm B, Kohl S, Weisschuh N, Martus P, Seeliger M, Muehlfriedel R, Paquet-Durand F, Tsang SH, Bartz-Schmidt KU, Ueffing M, Zrenner E, Biel M, Wissinger B, Michalakis S; RD-Cure Consortium. Reichel FF, et al. Among authors: seitz i. Br J Ophthalmol. 2026 Jan 22;110(2):173-179. doi: 10.1136/bjo-2024-326480. Br J Ophthalmol. 2026. PMID: 40825661 Free PMC article. Clinical Trial.
Safety of Human USH1C Transgene Expression Following Subretinal Injection in Wild-Type Pigs.
Kiraly P, Klein J, Seitz IP, Reichel FF, Peters T, Ardan T, Juhasova J, Juhás S, Ellederova Z, Nemesh Y, Nyshchuk R, Klymiuk N, Nagel-Wolfrum K, Winslow AR, Wolfrum U, Motlik J, Fischer MD. Kiraly P, et al. Among authors: seitz ip. Invest Ophthalmol Vis Sci. 2025 Jan 2;66(1):48. doi: 10.1167/iovs.66.1.48. Invest Ophthalmol Vis Sci. 2025. PMID: 39836403 Free PMC article.
32 results