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Deciphering the Role of microRNAs: Unveiling Clinical Biomarkers and Therapeutic Avenues in Atrial Fibrillation and Associated Stroke-A Systematic Review.
Boxhammer E, Dienhart C, Rezar R, Hoppe UC, Lichtenauer M. Boxhammer E, et al. Int J Mol Sci. 2024 May 20;25(10):5568. doi: 10.3390/ijms25105568. Int J Mol Sci. 2024. PMID: 38791605 Free PMC article. Review.
Numerous studies have focused on the expression of miRNA patterns with respect to atrial fibrillation (AF) or acute ischemic stroke (AIS) However, only a few studies have addressed the expression pattern of miRNAs in patients with AF and AIS in order to provide not only preven
Numerous studies have focused on the expression of miRNA patterns with respect to atrial fibrillation (AF) or acute ischemic stroke (AIS) Ho …
Association between depression and stroke risk in adults: a systematic review and meta-analysis.
Ashraf F, Mustafa MS, Shafique MA, Haseeb A, Mussarat A, Noorani A, Sohail Rangwala B, Kashif Rasool F, Siddiq MA, Iqbal J. Ashraf F, et al. Front Neurol. 2024 Apr 25;15:1331300. doi: 10.3389/fneur.2024.1331300. eCollection 2024. Front Neurol. 2024. PMID: 38725648 Free PMC article.
Given the severe consequences of stroke in individuals with depression, early detection and intervention should be prioritized to prevent it. SYSTEMATIC REVIEW REGISTRATION: Prospero (CRD42023472136)....
Given the severe consequences of stroke in individuals with depression, early detection and intervention should be prioritized to prevent
Development of insomnia in patients with stroke: A systematic review and meta-analysis.
Yang J, Lin A, Tan Q, Dou W, Wu J, Zhang Y, Lin H, Wei B, Huang J, Xie J. Yang J, et al. PLoS One. 2024 Apr 10;19(4):e0297941. doi: 10.1371/journal.pone.0297941. eCollection 2024. PLoS One. 2024. PMID: 38598535 Free PMC article.
Early understanding of the relationship between stroke and post-stroke insomnia can provide clinical evidence for preventing and treating post-stroke insomnia. This study was to investigate the prevalence of insomnia in patients with stroke. ...
Early understanding of the relationship between stroke and post-stroke insomnia can provide clinical evidence for preventing and trea …
Remote ischemic conditioning after stroke: Research progress in clinical study.
Jiang B, Wang X, Ma J, Fayyaz A, Wang L, Qin P, Ding Y, Ji X, Li S. Jiang B, et al. CNS Neurosci Ther. 2024 Apr;30(4):e14507. doi: 10.1111/cns.14507. Epub 2023 Nov 6. CNS Neurosci Ther. 2024. PMID: 37927203 Free PMC article. Review.
BACKGROUND AND PURPOSE: Stroke is a leading cause of global morbidity and mortality, indicating the necessity and urgency of effective prevention and treatment. Remote ischemic conditioning (RIC) is a convenient, simple, non-intrusive, and effective method that can be easi …
BACKGROUND AND PURPOSE: Stroke is a leading cause of global morbidity and mortality, indicating the necessity and urgency of effective pr
Elevated troponin levels as a predictor of mortality in patients with acute stroke: a systematic review and meta-analysis.
Gulia A, Srivastava M, Kumar P. Gulia A, et al. Front Neurol. 2024 Mar 25;15:1351925. doi: 10.3389/fneur.2024.1351925. eCollection 2024. Front Neurol. 2024. PMID: 38590721 Free PMC article.
Further prospective studies are needed to validate our findings along with exploring the preventive management of mortality in acute stroke settings....
Further prospective studies are needed to validate our findings along with exploring the preventive management of mortality in acute …
Comparative Effectiveness and Safety of Direct Oral Anticoagulants Compared with Warfarin in Patients with Low Bodyweight who have Atrial Fibrillation: A Systematic Review and Meta-analysis.
Elshafei MN, El-Bardissy A, Salem M, Abdelmoneim MS, Khalil A, Elhadad S, Danjuma M. Elshafei MN, et al. Am J Cardiovasc Drugs. 2024 Mar;24(2):255-271. doi: 10.1007/s40256-024-00628-6. Epub 2024 Feb 22. Am J Cardiovasc Drugs. 2024. PMID: 38386247 Free PMC article.

However, residual uncertainty remains regarding their use in preventing stroke in patients with low bodyweight [< 60 kg or body mass index (BMI) < 18 kg/m(2)]. We have carried out pooled systematic analyses of published studies to determine the efficacy and safety of

However, residual uncertainty remains regarding their use in preventing stroke in patients with low bodyweight [< 60 kg or body ma …
European stroke organisation (ESO) guideline on cerebral small vessel disease, part 2, lacunar ischaemic stroke.
Wardlaw JM, Chabriat H, de Leeuw FE, Debette S, Dichgans M, Doubal F, Jokinen H, Katsanos AH, Ornello R, Pantoni L, Pasi M, Pavlovic AM, Rudilosso S, Schmidt R, Staals J, Taylor-Rowan M, Hussain S, Lindgren AG. Wardlaw JM, et al. Eur Stroke J. 2024 Mar;9(1):5-68. doi: 10.1177/23969873231219416. Epub 2024 Feb 21. Eur Stroke J. 2024. PMID: 38380638 Free PMC article.
This European Stroke Organisation (ESO) guideline provides evidence-based recommendations to assist with clinical decisions about management of lacunar ischaemic stroke to prevent adverse clinical outcomes. The guideline was developed according to ESO standard operating pr …
This European Stroke Organisation (ESO) guideline provides evidence-based recommendations to assist with clinical decisions about management …
Comparative Effect of Glucose-Lowering Drugs for Type 2 Diabetes Mellitus on Stroke Prevention: A Systematic Review and Network Meta-Analysis.
Kim JS, Lee G, Park KI, Oh SW. Kim JS, et al. Diabetes Metab J. 2024 Mar;48(2):312-320. doi: 10.4093/dmj.2022.0421. Epub 2024 Jan 26. Diabetes Metab J. 2024. PMID: 38273787 Free PMC article.
BACKGRUOUND: There is still a lack of research on which diabetic drugs are more effective in preventing stroke. Our network metaanalysis aimed to compare cerebrovascular benefits among glucose-lowering treatments. ...CONCLUSION: SGLT-2 inhibitors and GLP-1 agonists were sh …
BACKGRUOUND: There is still a lack of research on which diabetic drugs are more effective in preventing stroke. Our network metaanaly …
Safety and efficacy of percutaneous Watchman 2.5 device versus Amplatzer Amulet for left atrial appendage closure in patients with non-valvular atrial fibrillation: A systematic review and study-level meta-analysis.
Yasmin F, Ali E, Moeed A, Zaidi F, Umar M, Virwani V. Yasmin F, et al. PLoS One. 2024 Feb 14;19(2):e0295804. doi: 10.1371/journal.pone.0295804. eCollection 2024. PLoS One. 2024. PMID: 38354181 Free PMC article.
Watchman Generation 2.5 and Amplatzer Amulet are the two most popular used devices for preventing stroke in patients with NVAF. We sought to compare safety and efficacy outcomes between Watchman 2.5 and Amplatzer Amulet in patients undergoing LAAC procedure. ...
Watchman Generation 2.5 and Amplatzer Amulet are the two most popular used devices for preventing stroke in patients with NVAF. We so …
Advances in balance training to prevent falls in stroke patients: a scoping review.
Chen K, Zhu S, Tang Y, Lan F, Liu Z. Chen K, et al. Front Neurol. 2024 Feb 5;15:1167954. doi: 10.3389/fneur.2024.1167954. eCollection 2024. Front Neurol. 2024. PMID: 38375467 Free PMC article.
OBJECTIVE: To summarize the status and characteristics of the available evidence, research gaps, and future research priorities for preventing falls in stroke patients through balance training. METHODS: We used a scoping review framework. ...The future researches should ex …
OBJECTIVE: To summarize the status and characteristics of the available evidence, research gaps, and future research priorities for preve
Association between ambient temperature and stroke risk in high-risk populations: a systematic review.
Danh N, Ho C, Ford E, Zhang J, Hong H, Reid C, Xu D. Danh N, et al. Front Neurol. 2024 Jan 8;14:1323224. doi: 10.3389/fneur.2023.1323224. eCollection 2023. Front Neurol. 2024. PMID: 38259643 Free PMC article.
This evidence implies the need to establish clinical guidelines for preventive intervention in patients with high stroke risks during extreme ambient temperatures....
This evidence implies the need to establish clinical guidelines for preventive intervention in patients with high stroke risks during …
Risk factors for cognitive impairment and dementia after stroke: a systematic review and meta-analysis.
Filler J, Georgakis MK, Dichgans M. Filler J, et al. Lancet Healthy Longev. 2024 Jan;5(1):e31-e44. doi: 10.1016/S2666-7568(23)00217-9. Epub 2023 Dec 12. Lancet Healthy Longev. 2024. PMID: 38101426 Free article.
Future trials should explore these risk factors as potential targets for prevention of PSCI and PSD. FUNDING: German Research Foundation....
Future trials should explore these risk factors as potential targets for prevention of PSCI and PSD. FUNDING: German Research Foundat …
Does Endovascular Thrombectomy(ET) plus tirofiban benefit stroke patients: A systematic review and meta-analysis.
Xie H, Chen Y, Ge W, Xu X, Liu C, Lan Z, Yang Y. Xie H, et al. J Stroke Cerebrovasc Dis. 2024 Jan;33(1):107494. doi: 10.1016/j.jstrokecerebrovasdis.2023.107494. Epub 2023 Nov 29. J Stroke Cerebrovasc Dis. 2024. PMID: 38035642 Free article.
BACKGROUND: Ischemic stroke is the second leading cause of death worldwide. Endovascular thrombectomy (ET) has been shown to prevent disability in a proportion of patients. The use of tirofiban in patients undergoing ET after acute stroke has resulted in improved patient f …
BACKGROUND: Ischemic stroke is the second leading cause of death worldwide. Endovascular thrombectomy (ET) has been shown to prevent
Cardiovascular Risk Factors, Cerebral Small Vessel Disease, and Subsequent Risk of Stroke in Patients with Idiopathic Sudden Sensorineural Hearing Loss: Systematic Review and Meta-Analyses of the Current Literature.
Oussoren FK, Schermer TR, van Leeuwen RB, Bruintjes TD. Oussoren FK, et al. Audiol Neurootol. 2024;29(1):1-29. doi: 10.1159/000530686. Epub 2023 Aug 9. Audiol Neurootol. 2024. PMID: 37557093 Free PMC article.
Prospective studies with larger study populations are needed to confirm the associations between generalized cardiovascular disease and iSSNHL and to assess whether these patients benefit from cardiovascular risk management to prevent future cardiovascular and cerebrovascu …
Prospective studies with larger study populations are needed to confirm the associations between generalized cardiovascular disease and iSSN …
Interventions for Behaviour Change and Self-Management of Risk in Stroke Secondary Prevention: An Overview of Reviews.
Hall P, Lawrence M, Blake C, Lennon O. Hall P, et al. Cerebrovasc Dis. 2024;53(1):1-13. doi: 10.1159/000531138. Epub 2023 May 25. Cerebrovasc Dis. 2024. PMID: 37231867 Free article.
INTRODUCTION: Optimised secondary prevention strategies that include lifestyle change are recommended after stroke. ...CONCLUSION: Effective strategies to redress risk-related health behaviours are required in stroke survivors to complement current pharmacological secondar …
INTRODUCTION: Optimised secondary prevention strategies that include lifestyle change are recommended after stroke. ...CONCLUSION: Ef …
Effects of oral anticoagulation in people with atrial fibrillation after spontaneous intracranial haemorrhage (COCROACH): prospective, individual participant data meta-analysis of randomised trials.
Al-Shahi Salman R, Stephen J, Tierney JF, Lewis SC, Newby DE, Parry-Jones AR, White PM, Connolly SJ, Benavente OR, Dowlatshahi D, Cordonnier C, Viscoli CM, Sheth KN, Kamel H, Veltkamp R, Larsen KT, Hofmeijer J, Kerkhoff H, Schreuder FHBM, Shoamanesh A, Klijn CJM, van der Worp HB; Collaboration of Controlled Randomised Trials of Long-Term Oral Antithrombotic Agents After Spontaneous Intracranial Haemorrhage (COCROACH). Al-Shahi Salman R, et al. Lancet Neurol. 2023 Dec;22(12):1140-1149. doi: 10.1016/S1474-4422(23)00315-0. Epub 2023 Oct 12. Lancet Neurol. 2023. PMID: 37839434 Free article.
BACKGROUND: The safety and efficacy of oral anticoagulation for prevention of major adverse cardiovascular events in people with atrial fibrillation and spontaneous intracranial haemorrhage are uncertain. ...We included clinical trials if they were registered, randomised, …
BACKGROUND: The safety and efficacy of oral anticoagulation for prevention of major adverse cardiovascular events in people with atri …
Impact of influenza, herpes zoster, and pneumococcal vaccinations on the incidence of cardiovascular events in subjects aged over 65 years: a systematic review.
Addario A, Célarier T, Bongue B, Barth N, Gavazzi G, Botelho-Nevers E. Addario A, et al. Geroscience. 2023 Dec;45(6):3419-3447. doi: 10.1007/s11357-023-00807-4. Epub 2023 Jun 3. Geroscience. 2023. PMID: 37269492 Free PMC article. Review.
This review outlines the benefits of the vaccines mentioned above beyond their preventive action on infectious diseases. It is intended for health professionals who wish to inform and advise their elderly patients....
This review outlines the benefits of the vaccines mentioned above beyond their preventive action on infectious diseases. It is intend …
Sinus node dysfunction and stroke risk: a systematic review and meta-analysis.
Dong H, Chen H, Hidru TH, Xia Y, Yang X. Dong H, et al. BMJ Open. 2023 Nov 17;13(11):e076499. doi: 10.1136/bmjopen-2023-076499. BMJ Open. 2023. PMID: 37977871 Free PMC article.
Future studies are needed to investigate whether interventions targeting stroke prevention, such as anticoagulation therapy, can help to prevent stroke in patients with SND. ...
Future studies are needed to investigate whether interventions targeting stroke prevention, such as anticoagulation therapy, can help …
Comprehensive systematic review and meta-analysis on anticoagulants and aspirin for stroke prevention in non-valvular atrial fibrillation patients.
Xu ZQ, Xu ZH, Zhang N. Xu ZQ, et al. Eur Rev Med Pharmacol Sci. 2023 Nov;27(22):11002-11012. doi: 10.26355/eurrev_202311_34469. Eur Rev Med Pharmacol Sci. 2023. PMID: 38039031 Free article.
OBJECTIVE: Non-valvular atrial fibrillation (NVAF) is a common manifestation of cardiac arrhythmia, whose significance is heightened in the context of an aging global population and changing lifestyles, leading to an increased incidence. Stroke prevention in NVAF is a comp …
OBJECTIVE: Non-valvular atrial fibrillation (NVAF) is a common manifestation of cardiac arrhythmia, whose significance is heightened in the …
Stroke epidemiology and outcomes of stroke patients in Nepal: a systematic review and meta-analysis.
Paudel R, Tunkl C, Shrestha S, Subedi RC, Adhikari A, Thapa L, Gajurel BP, Chandra A, Kharel G, Jalan P, Phuyal S, Pokharel BR, Acharya S, Bogati K, Jha P, Kharbuja N, Gumbinger C. Paudel R, et al. BMC Neurol. 2023 Sep 25;23(1):337. doi: 10.1186/s12883-023-03382-5. BMC Neurol. 2023. PMID: 37749496 Free PMC article.
CONCLUSION: The provision of stroke care in Nepal needs to catch up to international standards, and our systematic review demonstrated the need to improve access to quality stroke care. Dedicated studies on establishing stroke care units, prevention, rehabilitation, and st …
CONCLUSION: The provision of stroke care in Nepal needs to catch up to international standards, and our systematic review demonstrated the n …
Disparities in Stroke Incidence Over Time by Sex and Age in Latin America and the Caribbean Region 1997 to 2021: A Systematic Review and Meta-Analysis.
Nuñez M, Delfino C, Asenjo-Lobos C, Schilling A, Lavados P, Anderson CS, Muñoz Venturelli P. Nuñez M, et al. J Am Heart Assoc. 2023 Sep 5;12(17):e029800. doi: 10.1161/JAHA.123.029800. Epub 2023 Aug 29. J Am Heart Assoc. 2023. PMID: 37642019 Free PMC article.
Further investigation of the explanatory variables is required to ameliorate stroke prevention and inform local decision-makers. Registration URL: https://www.crd.york.ac.uk/prospero/ Identifier: CRD42022332563....
Further investigation of the explanatory variables is required to ameliorate stroke prevention and inform local decision-makers. Regi …
Bibliometric analysis and visualized study of research on autophagy in ischemic stroke.
Chen J, Chen G, Xu X, Chen L, Zhang J, Liu F. Chen J, et al. Front Pharmacol. 2023 Sep 4;14:1232114. doi: 10.3389/fphar.2023.1232114. eCollection 2023. Front Pharmacol. 2023. PMID: 37731738 Free PMC article.
Subsequent trends in this special field are likely to identify and develop novel autophagy-targeted therapy strategies to effectively prevent and treat ischemic stroke....
Subsequent trends in this special field are likely to identify and develop novel autophagy-targeted therapy strategies to effectively pre
Hypertensive disorders of pregnancy and long-term risk of maternal stroke-a systematic review and meta-analysis.
Brohan MP, Daly FP, Kelly L, McCarthy FP, Khashan AS, Kublickiene K, Barrett PM. Brohan MP, et al. Am J Obstet Gynecol. 2023 Sep;229(3):248-268. doi: 10.1016/j.ajog.2023.03.034. Epub 2023 Mar 27. Am J Obstet Gynecol. 2023. PMID: 36990309 Free article. Review.
CONCLUSION: In this meta-analysis, exposure to hypertensive disorders of pregnancy, including preeclampsia and gestational hypertension, seems to be associated with an increased risk for any stroke and ischemic stroke among parous patients in later life. Preventive interve …
CONCLUSION: In this meta-analysis, exposure to hypertensive disorders of pregnancy, including preeclampsia and gestational hypertension, see …
Sodium-Glucose Cotransporter-2 Inhibitors and Primary Prevention of Atherosclerotic Cardiovascular Disease: A Meta-Analysis of Randomized Trials and Systematic Review.
Rahman H, Khan SU, Lone AN, Ghosh P, Kunduru M, Sharma S, Sattur S, Kaluski E. Rahman H, et al. J Am Heart Assoc. 2023 Aug 15;12(16):e030578. doi: 10.1161/JAHA.123.030578. Epub 2023 Aug 10. J Am Heart Assoc. 2023. PMID: 37581396 Free PMC article.
Methods and Results Large-scale cardiovascular outcome randomized controlled trials or their prespecified subgroup analyses were selected, evaluating SGLT2 inhibitors versus placebo for primary prevention of ASCVD (inception, March 2023). The primary outcome was atheroscle …
Methods and Results Large-scale cardiovascular outcome randomized controlled trials or their prespecified subgroup analyses were selected, e …
Unraveling Mechanisms of Cryptogenic Stroke at the Genetic Level: A Systematic Literature Review.
Ernst J, Ehrenreich H, Weissenborn K, Grosse GM. Ernst J, et al. J Am Heart Assoc. 2023 Aug;12(15):e029843. doi: 10.1161/JAHA.123.029843. Epub 2023 Jul 25. J Am Heart Assoc. 2023. PMID: 37489722 Free PMC article.
Background A substantial proportion of ischemic strokes remain cryptogenic, which has important implications for secondary prevention. Identifying genetic variants related to mechanisms of stroke causes may provide a chance to clarify the actual causes of cryptogenic strok …
Background A substantial proportion of ischemic strokes remain cryptogenic, which has important implications for secondary prevention
Cost Effectiveness of Strategies to Manage Atrial Fibrillation in Middle- and High-Income Countries: A Systematic Review.
Okafor C, Byrnes J, Stewart S, Scuffham P, Afoakwah C. Okafor C, et al. Pharmacoeconomics. 2023 Aug;41(8):913-943. doi: 10.1007/s40273-023-01276-5. Epub 2023 May 19. Pharmacoeconomics. 2023. PMID: 37204698 Free PMC article.
In high-income countries, apixaban was predominantly cost effective for stroke prevention in patients at low and moderate risk of stroke, while left atrial appendage closure (LAAC) was cost effective in patients at high risk of stroke. ...In middle-income countries, apixab …
In high-income countries, apixaban was predominantly cost effective for stroke prevention in patients at low and moderate risk of str …
Effect of implantable cardiac monitors on preventing stroke: A systematic review and meta-analysis of randomized clinical trials.
He J, Jiang Y, Xiao Y, Hao P, Li T, Peng L, Feng Y, Cheng X, Deng H, Wang P, Chong W, Hai Y, Chen L, You C, Jia L, Fang F, Yu S, Zhang Y. He J, et al. PLoS One. 2023 Jul 20;18(7):e0287318. doi: 10.1371/journal.pone.0287318. eCollection 2023. PLoS One. 2023. PMID: 37471323 Free PMC article.
We performed a systematic review and meta-analysis to investigate whether ICM can prevent stroke in patients with prior stroke and risk factors for stroke. ...
We performed a systematic review and meta-analysis to investigate whether ICM can prevent stroke in patients with prior stroke and ri …
Cerebral embolic protection during transcatheter aortic valve replacement: a systematic review and meta-analysis of propensity score matched and randomized controlled trials using the Sentinel cerebral embolic protection device.
Wolfrum M, Handerer IJ, Moccetti F, Schmeisser A, Braun-Dullaeus RC, Toggweiler S. Wolfrum M, et al. BMC Cardiovasc Disord. 2023 Jun 17;23(1):306. doi: 10.1186/s12872-023-03338-0. BMC Cardiovasc Disord. 2023. PMID: 37330463 Free PMC article.
We performed a systematic review and meta-analysis of propensity score matched (PSM) and randomized controlled trials (RCT) investigating the effect of the Sentinel CEP to prevent strokes during TAVR. METHODS: Eligible trials were searched through PubMed, ISI Web of scienc …
We performed a systematic review and meta-analysis of propensity score matched (PSM) and randomized controlled trials (RCT) investigating th …
Strategies for specialty training of healthcare professionals in low-resource settings: a systematic review on evidence from stroke care.
Habibi J, Bosch J, Bidulka P, Belson S, DePaul V, Gandhi D, Kumurenzi A, Melifonwu R, Pandian J, Langhorne P, Solomon JM, Dawar D, Carroll S, Urimubenshi G, Kaddumukasa M, Hamilton L. Habibi J, et al. BMC Med Educ. 2023 Jun 16;23(1):442. doi: 10.1186/s12909-023-04431-w. BMC Med Educ. 2023. PMID: 37328888 Free PMC article.
Multidimensional education demonstrated an overall care quality improvement and increased prescriptions for evidence-based therapies, although, there were no significant differences in secondary prevention efforts, stroke reoccurrence or mortality rates. CONCLUSIONS: The " …
Multidimensional education demonstrated an overall care quality improvement and increased prescriptions for evidence-based therapies, althou …
Efficacy and safety of inclisiran in stroke or cerebrovascular disease prevention: a systematic review and meta-analysis of randomized controlled trials.
Luo M, Liu Y, Xu X, Liu K, Shen C, Hu H, He Z, Wu F. Luo M, et al. Front Pharmacol. 2023 Jun 13;14:1158274. doi: 10.3389/fphar.2023.1158274. eCollection 2023. Front Pharmacol. 2023. PMID: 37383716 Free PMC article.
Aims: As the impact of inclisiran in stroke prevention in atherosclerotic cardiovascular disease (ASCVD) patients or those at high risk of ASCVD is still unclear, we conducted a systematic review and meta-analysis of randomized controlled trials (RCT) to quantify the effec …
Aims: As the impact of inclisiran in stroke prevention in atherosclerotic cardiovascular disease (ASCVD) patients or those at high ri …
Interventions for improving psychosocial well-being after stroke: A systematic review.
van Nimwegen D, Hjelle EG, Bragstad LK, Kirkevold M, Sveen U, Hafsteinsdóttir T, Schoonhoven L, Visser-Meily J, de Man-van Ginkel JM. van Nimwegen D, et al. Int J Nurs Stud. 2023 Jun;142:104492. doi: 10.1016/j.ijnurstu.2023.104492. Epub 2023 Mar 28. Int J Nurs Stud. 2023. PMID: 37084476 Free article.
Effective intervention topics were found to be mood, recovery, coping, emotions, consequences/problems after stroke, values and needs, risk factors and secondary prevention, self-management, and medication management. Active information and physical exercise were identifie …
Effective intervention topics were found to be mood, recovery, coping, emotions, consequences/problems after stroke, values and needs, risk …
A systematic review and synthesis of global stroke guidelines on behalf of the World Stroke Organization.
Mead GE, Sposato LA, Sampaio Silva G, Yperzeele L, Wu S, Kutlubaev M, Cheyne J, Wahab K, Urrutia VC, Sharma VK, Sylaja PN, Hill K, Steiner T, Liebeskind DS, Rabinstein AA. Mead GE, et al. Int J Stroke. 2023 Jun;18(5):499-531. doi: 10.1177/17474930231156753. Epub 2023 Mar 1. Int J Stroke. 2023. PMID: 36725717 Free PMC article.
AIMS: To systematically review the literature to identify stroke guidelines (excluding primary stroke prevention and subarachnoid hemorrhage) since 1 January 2011, evaluate quality (The international Appraisal of Guidelines, Research and Evaluation (AGREE II)), tabulate st …
AIMS: To systematically review the literature to identify stroke guidelines (excluding primary stroke prevention and subarachnoid hem …
Anticoagulation use in perioperative atrial fibrillation after noncardiac surgery: a systematic review and meta-analysis.
Ke Wang M, Heo R, Meyre PB, Blum S, Park L, Birchenough L, Vuong K, McIntyre WF, Healey JS, Devereaux PJ, McMullen M, Mrkobrada M, Pinilla-Echeverri N, Styles K, Conen D. Ke Wang M, et al. Swiss Med Wkly. 2023 Apr 18;153:40056. doi: 10.57187/smw.2023.40056. Swiss Med Wkly. 2023. PMID: 37080190 Free article.
BACKGROUND: Perioperative atrial fibrillation is associated with an increased risk of stroke, myocardial infarction, and death after noncardiac surgery. Anticoagulation therapy is effective for stroke prevention in nonsurgical atrial fibrillation, but its efficacy and safe …
BACKGROUND: Perioperative atrial fibrillation is associated with an increased risk of stroke, myocardial infarction, and death after noncard …
The Role of Clinical Decision Support Systems in Preventing Stroke in Primary Care: A Systematic Review.
Alasiri SF, Douiri A, Altukistani S, Porat T, Mousa O. Alasiri SF, et al. Perspect Health Inf Manag. 2023 Apr 1;20(2):1d. eCollection 2023 Spring. Perspect Health Inf Manag. 2023. PMID: 37293480 Free PMC article.
This systematic review evaluates evidence of the available CDSS developed and tested to support the decision-making process in primary healthcare for stroke prevention and barriers to practical implementations in primary care settings. ...This review found that CDSS facili …
This systematic review evaluates evidence of the available CDSS developed and tested to support the decision-making process in primary healt …
Post-stroke sleep disturbance and recurrent cardiovascular and cerebrovascular events: A systematic review and meta-analysis.
Hale E, Gottlieb E, Usseglio J, Shechter A. Hale E, et al. Sleep Med. 2023 Apr;104:29-41. doi: 10.1016/j.sleep.2023.02.019. Epub 2023 Feb 20. Sleep Med. 2023. PMID: 36889030 Free PMC article. Review.
From the limited number of studies conducted to date, insomnia symptoms/poor sleep quality and long sleep duration were associated with increased risk. Sleep, a modifiable behavior, may be a secondary prevention target to reduce the risk of recurrent event and death follow …
From the limited number of studies conducted to date, insomnia symptoms/poor sleep quality and long sleep duration were associated with incr …
Comparing benefits from sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide-1 receptor agonists in randomized clinical trials: a network meta-analysis.
Sabouret P, Bocchino PP, Angelini F, D'Ascenzo F, Galati G, Fysekidis M, DE Ferrari GM, Fischman DL, Bhatt DL, Biondi-Zoccai G. Sabouret P, et al. Minerva Cardiol Angiol. 2023 Apr;71(2):199-207. doi: 10.23736/S2724-5683.22.05900-2. Epub 2022 Feb 23. Minerva Cardiol Angiol. 2023. PMID: 35195376 Free article.
Both classes similarly reduced MI rate, cardiovascular and all-cause mortality compared with OMT; stroke reduction was only observed with GLP1-RA with no difference in the indirect comparison with SGLT2i; conversely, only SGLT2i were effective in preventing HFH. Both GLP1- …
Both classes similarly reduced MI rate, cardiovascular and all-cause mortality compared with OMT; stroke reduction was only observed with GL …
Economic Evaluation of Clinical, Nutritional and Rehabilitation Interventions on Oropharyngeal Dysphagia after Stroke: A Systematic Review.
Marin S, Ortega O, Serra-Prat M, Valls E, Pérez-Cordón L, Clavé P. Marin S, et al. Nutrients. 2023 Mar 31;15(7):1714. doi: 10.3390/nu15071714. Nutrients. 2023. PMID: 37049553 Free PMC article. Review.
CONCLUSIONS: Included studies suggest that healthcare interventions aiming to prevent OD complications are cost-effective. However, studies assessing novel strategies are needed....
CONCLUSIONS: Included studies suggest that healthcare interventions aiming to prevent OD complications are cost-effective. However, s …
Comparison of seven popular structured dietary programmes and risk of mortality and major cardiovascular events in patients at increased cardiovascular risk: systematic review and network meta-analysis.
Karam G, Agarwal A, Sadeghirad B, Jalink M, Hitchcock CL, Ge L, Kiflen R, Ahmed W, Zea AM, Milenkovic J, Chedrawe MA, Rabassa M, El Dib R, Goldenberg JZ, Guyatt GH, Boyce E, Johnston BC. Karam G, et al. BMJ. 2023 Mar 29;380:e072003. doi: 10.1136/bmj-2022-072003. BMJ. 2023. PMID: 36990505 Free PMC article.
OBJECTIVE: To determine the relative efficacy of structured named diet and health behaviour programmes (dietary programmes) for prevention of mortality and major cardiovascular events in patients at increased risk of cardiovascular disease. ...Based on moderate certainty e …
OBJECTIVE: To determine the relative efficacy of structured named diet and health behaviour programmes (dietary programmes) for preventio
How often is occult atrial fibrillation in cryptogenic stroke causal vs. incidental? A meta-analysis.
Chaisinanunkul N, Khurshid S, Buck BH, Rabinstein AA, Anderson CD, Hill MD, Fugate JE, Saver JL. Chaisinanunkul N, et al. Front Neurol. 2023 Mar 14;14:1103664. doi: 10.3389/fneur.2023.1103664. eCollection 2023. Front Neurol. 2023. PMID: 36998779 Free PMC article.
These findings suggest that anticoagulation therapy may be beneficial to prevent recurrent stroke in a substantial proportion of patients with CS found to have occult AF....
These findings suggest that anticoagulation therapy may be beneficial to prevent recurrent stroke in a substantial proportion of pati …
Soy Consumption and the Risk of Type 2 Diabetes and Cardiovascular Diseases: A Systematic Review and Meta-Analysis.
Zuo X, Zhao R, Wu M, Wan Q, Li T. Zuo X, et al. Nutrients. 2023 Mar 10;15(6):1358. doi: 10.3390/nu15061358. Nutrients. 2023. PMID: 36986086 Free PMC article. Review.
This meta-analysis demonstrated that soy consumption was negatively associated with the risks of T2D and CVDs and a specific quantity of soy products was the most beneficial for the prevention of T2D and CVDs. This study has been registered on PROSPERO (registration number …
This meta-analysis demonstrated that soy consumption was negatively associated with the risks of T2D and CVDs and a specific quantity of soy …
Prolonged cardiac monitoring for stroke prevention: A systematic review and meta-analysis of randomized-controlled clinical trials.
Tsivgoulis G, Palaiodimou L, Triantafyllou S, Köhrmann M, Dilaveris P, Tsioufis K, Magiorkinis G, Krogias C, Schellinger PD, Caso V, Paciaroni M, Sharma M, Lemmens R, Gladstone DJ, Sanna T, Wachter R, Filippatos G, Katsanos AH. Tsivgoulis G, et al. Eur Stroke J. 2023 Mar;8(1):106-116. doi: 10.1177/23969873221139410. Epub 2022 Nov 21. Eur Stroke J. 2023. PMID: 37021198 Free PMC article.
However, when RCTs assessing PCM in both primary and secondary prevention settings were excluded or when RCTs investigating PCM with a duration of 7 days or less were included, the association between PCM and reduction of IS did not retain its statistical significance. ... …
However, when RCTs assessing PCM in both primary and secondary prevention settings were excluded or when RCTs investigating PCM with …
Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis.
Luo J, Wang T, Yang K, Wang X, Xu R, Gong H, Zhang X, Wang J, Yang R, Gao P, Ma Y, Jiao L. Luo J, et al. Cochrane Database Syst Rev. 2023 Feb 3;2(2):CD013267. doi: 10.1002/14651858.CD013267.pub3. Cochrane Database Syst Rev. 2023. PMID: 36738471 Free PMC article. Review.
Endovascular therapy (ET) and conventional medical treatment (CMT) may prevent recurrent ischaemic stroke caused by ICAS. However, there is no consensus on the best treatment for people with ICAS. ...
Endovascular therapy (ET) and conventional medical treatment (CMT) may prevent recurrent ischaemic stroke caused by ICAS. However, th …
Is cognitive reserve associated with the prevention of cognitive decline after stroke? A Systematic review and meta-analysis.
Contador I, Alzola P, Stern Y, de la Torre-Luque A, Bermejo-Pareja F, Fernández-Calvo B. Contador I, et al. Ageing Res Rev. 2023 Feb;84:101814. doi: 10.1016/j.arr.2022.101814. Epub 2022 Dec 5. Ageing Res Rev. 2023. PMID: 36473672 Free article. Review.
Second, a main cognitive change effect was found, pointing to greater cognitive change after stroke in those with low vs. high CR. CONCLUSIONS: Our findings emphasize that CR may prevent cognitive decline after stroke, but this effect can be modulated by different factors …
Second, a main cognitive change effect was found, pointing to greater cognitive change after stroke in those with low vs. high CR. CONCLUSIO …
Should we adjudicate outcomes in stroke trials? A systematic review.
Godolphin PJ, Bath PM, Montgomery AA. Godolphin PJ, et al. Int J Stroke. 2023 Feb;18(2):154-162. doi: 10.1177/17474930221094682. Epub 2022 May 10. Int J Stroke. 2023. PMID: 35373672 Free article. Review.
We found that the cost of adjudication could be upward of 100,000 for medium to large prevention trials. These findings suggest that the cost of central adjudication may outweigh the advantages it brings in many cases. ...
We found that the cost of adjudication could be upward of 100,000 for medium to large prevention trials. These findings suggest that …
Secondary Stroke Risk Reduction in Black Adults: a Systematic Review.
Cao C, Jain N, Lu E, Sajatovic M, Still CH. Cao C, et al. J Racial Ethn Health Disparities. 2023 Feb;10(1):306-318. doi: 10.1007/s40615-021-01221-2. Epub 2022 Jan 14. J Racial Ethn Health Disparities. 2023. PMID: 35032010 Free PMC article. Review.
Effect of mobile application types on stroke rehabilitation: a systematic review.
Szeto SG, Wan H, Alavinia M, Dukelow S, MacNeill H. Szeto SG, et al. J Neuroeng Rehabil. 2023 Jan 24;20(1):12. doi: 10.1186/s12984-023-01124-9. J Neuroeng Rehabil. 2023. PMID: 36694257 Free PMC article.
Data extrapolation mapped 5 mobile app types (therapy apps, education apps, rehab videos, reminders, and a combination of rehab videos with reminders) to stroke deficits (motor paresis, aphasia, neglect), adherence to exercise, activities of daily living (ADLs), quality of life, …
Data extrapolation mapped 5 mobile app types (therapy apps, education apps, rehab videos, reminders, and a combination of rehab videos with …
Outcomes and drivers of inappropriate dosing of non-vitamin K antagonist oral anticoagulants (NOACs) in patients with atrial fibrillation: a systematic review and meta-analysis.
Caso V, de Groot JR, Sanmartin Fernandez M, Segura T, Blomström-Lundqvist C, Hargroves D, Antoniou S, Williams H, Worsley A, Harris J, Caleyachetty A, Vardar B, Field P, Ruff CT. Caso V, et al. Heart. 2023 Jan 11;109(3):178-185. doi: 10.1136/heartjnl-2022-321114. Heart. 2023. PMID: 36316100 Free PMC article.
Peroxisome proliferator-activated receptor gamma agonists for preventing recurrent stroke and other vascular events in people with stroke or transient ischaemic attack.
Liu J, Wang LN. Liu J, et al. Cochrane Database Syst Rev. 2023 Jan 10;1(1):CD010693. doi: 10.1002/14651858.CD010693.pub6. Cochrane Database Syst Rev. 2023. PMID: 36625492 Free PMC article. Review.
OBJECTIVES: To assess the efficacy and safety of PPAR-gamma agonists in the secondary prevention of stroke and related vascular events for people with stroke or transient ischaemic attack (TIA). ...Further well-designed, double-blind RCTs with large samples are required to …
OBJECTIVES: To assess the efficacy and safety of PPAR-gamma agonists in the secondary prevention of stroke and related vascular event …
The Effect of Peri-Device Leaks on Ischaemic Stroke/Transient Ischaemic Attack/Systemic Embolism after Left Atrial Appendage Closure: A Systematic Review and Meta-Analysis.
He YG, Yang SH, Xu L, Wang Y, Qin XT, Chen PP, Zhao YJ. He YG, et al. Cardiology. 2023;148(6):581-592. doi: 10.1159/000532019. Epub 2023 Jul 17. Cardiology. 2023. PMID: 37459844 Free article.
BACKGROUND: Left atrial appendage closure (LAAC) is a safe and effective method for preventing embolic events in patients with non-valvular atrial fibrillation. ...
BACKGROUND: Left atrial appendage closure (LAAC) is a safe and effective method for preventing embolic events in patients with non-va …
Efficacy and Safety of Ticagrelor versus Aspirin and Clopidogrel for Stroke Prevention in Patients with Vascular Disease: A Systematic Review and Meta-Analysis.
Ma X, Li D, Liu S, Chen Y, Zhong P. Ma X, et al. Eur Neurol. 2023;86(4):229-241. doi: 10.1159/000530504. Epub 2023 Apr 17. Eur Neurol. 2023. PMID: 37068471 Free article.
CONCLUSION: Ticagrelor is slightly better than clopidogrel and aspirin in preventing stroke, especially ischemic stroke, with significant safety risks. ...
CONCLUSION: Ticagrelor is slightly better than clopidogrel and aspirin in preventing stroke, especially ischemic stroke, with signifi …
Prevalence and Risk Factors of Frailty in Stroke Patients: A Meta-Analysis and Systematic Review.
Huang YN, Yan FH, Wang XY, Chen XL, Chong HY, Su WL, Chen YR, Han L, Ma YX. Huang YN, et al. J Nutr Health Aging. 2023;27(2):96-102. doi: 10.1007/s12603-023-1879-z. J Nutr Health Aging. 2023. PMID: 36806864 Free article.
In the future, medical staff should pay attention to the early screening of frailty in high-risk groups and provide information on its prevention....
In the future, medical staff should pay attention to the early screening of frailty in high-risk groups and provide information on its pr
Association Between Traumatic Brain Injury and Increased Risk of Stroke: A Systematic Review and Meta-analysis.
Esterov D, Sperl MA, Hines EA, Kinzelman Vesely EA, Brown AW. Esterov D, et al. J Head Trauma Rehabil. 2023 Jan-Feb 01;38(1):E44-E55. doi: 10.1097/HTR.0000000000000785. Epub 2022 May 26. J Head Trauma Rehabil. 2023. PMID: 36594863 Free PMC article.
CONCLUSIONS: TBI, regardless of injury severity, was associated with a higher risk of stroke. To improve secondary stroke prevention strategies, future studies should classify TBI severity and type of stroke more precisely and determine long-term risk....
CONCLUSIONS: TBI, regardless of injury severity, was associated with a higher risk of stroke. To improve secondary stroke prevention
Patent foramen ovale and perioperative stroke in noncardiac surgery: a systematic review and meta-analysis.
Rais G, Vassallo P, Schorer R, Bollen Pinto B, Putzu A. Rais G, et al. Br J Anaesth. 2022 Dec;129(6):898-908. doi: 10.1016/j.bja.2022.06.036. Epub 2022 Aug 18. Br J Anaesth. 2022. PMID: 35987705 Free article. Review.
Prospective trials should further explore this association by systematically assessing patent foramen ovale and stroke prevalence and identifying a specific population at risk. This is crucial for the elaboration of prevention plans and may improve perioperative outcomes.. …
Prospective trials should further explore this association by systematically assessing patent foramen ovale and stroke prevalence and identi …
Is stroke incidence increased in survivors of adult cancers? A systematic review and meta-analysis.
Turner M, Murchie P, Derby S, Ong AY, Walji L, McLernon D, Macleod MJ, Adam R. Turner M, et al. J Cancer Surviv. 2022 Dec;16(6):1414-1448. doi: 10.1007/s11764-021-01122-7. Epub 2021 Nov 5. J Cancer Surviv. 2022. PMID: 34739710 Free PMC article. Review.
However, there is insufficient evidence to appropriately inform guidelines for specific stroke prevention or management for cancer patients. We conducted a systematic review and meta-analysis to describe and quantify stroke incidence in people living with and beyond cancer …
However, there is insufficient evidence to appropriately inform guidelines for specific stroke prevention or management for cancer pa …
Surgical decompression for malignant cerebral oedema after ischaemic stroke.
Dower A, Mulcahy M, Maharaj M, Chen H, Lim CED, Li Y, Sheridan M. Dower A, et al. Cochrane Database Syst Rev. 2022 Nov 16;11(11):CD014989. doi: 10.1002/14651858.CD014989.pub2. Cochrane Database Syst Rev. 2022. PMID: 36385224 Free PMC article. Review.
There was no consistent reporting of per-participant adverse event rates in any of the included studies, which prevented further analysis. AUTHORS' CONCLUSIONS: Surgical decompression improves outcomes in the management of malignant oedema after acute ischaemic stroke, inc …
There was no consistent reporting of per-participant adverse event rates in any of the included studies, which prevented further anal …
Effectiveness of exercise in reducing cerebral stroke risk factors: A systematic review and meta-analysis.
Men J, Wang W, Zhao J, Wen J, Hao Q, Li S, Zou S. Men J, et al. Medicine (Baltimore). 2022 Nov 11;101(45):e31861. doi: 10.1097/MD.0000000000031861. Medicine (Baltimore). 2022. PMID: 36397439 Free PMC article.
OBJECTIVES: This study aimed to explore the relationship between exercise and cerebral stroke and provide evidence for the prevention of cerebral stroke. MATERIALS/METHODS: All clinical trials of exercise intervention for atherosclerosis were systematically reviewed. ...
OBJECTIVES: This study aimed to explore the relationship between exercise and cerebral stroke and provide evidence for the prevention
Statin use and the risk of CVD events, stroke, and all-cause mortality in patients with diabetes: A systematic review and meta-analysis.
Yang XH, Zhang BL, Cheng Y, Fu SK, Jin HM. Yang XH, et al. Nutr Metab Cardiovasc Dis. 2022 Nov;32(11):2470-2482. doi: 10.1016/j.numecd.2022.07.018. Epub 2022 Aug 8. Nutr Metab Cardiovasc Dis. 2022. PMID: 36064686 Free article.
AIMS: Considering the lack of evidence on statin use and the risk of cardiovascular disease (CVD) in patients with diabetes in primary and secondary prevention, this study aimed to evaluate the effect of statin use in individuals with diabetes for primary and secondary …
AIMS: Considering the lack of evidence on statin use and the risk of cardiovascular disease (CVD) in patients with diabetes in primary and s …
Effectiveness and safety of intracranial events associated with the use of direct oral anticoagulants for atrial fibrillation: A systematic review and meta-analysis of 92 studies.
Archontakis-Barakakis P, Li W, Kalaitzoglou D, Tzelves L, Manolopoulos A, Giannopoulos S, Giamouzis G, Giannakoulas G, Batsidis A, Palaiodimos L, Ntaios G, Lip GYH, Kokkinidis DG. Archontakis-Barakakis P, et al. Br J Clin Pharmacol. 2022 Nov;88(11):4663-4675. doi: 10.1111/bcp.15464. Epub 2022 Aug 15. Br J Clin Pharmacol. 2022. PMID: 35853612 Free article. Review.
Patient's care bundle benefits to prevent stroke associated pneumonia: A meta-analysis with trial sequential analysis.
Guo F, Fan Q, Liu X, Sun D. Guo F, et al. Front Neurol. 2022 Oct 31;13:950662. doi: 10.3389/fneur.2022.950662. eCollection 2022. Front Neurol. 2022. PMID: 36388225 Free PMC article.
BACKGROUND: Patient's care bundle has been found to have a beneficial effect on refractory diseases, but the preventive effect of this strategy on stroke-associated pneumonia (SAP) remains unclear. ...Results of TSA confirmed that none of the findings could be significantl …
BACKGROUND: Patient's care bundle has been found to have a beneficial effect on refractory diseases, but the preventive effect of thi …
Physical therapy interventions for the correction of equinus foot deformity in post-stroke patients with triceps spasticity: A scoping review.
Campanini I, Bò MC, Salsi F, Bassi MC, Damiano B, Scaltriti S, Lusuardi M, Merlo A. Campanini I, et al. Front Neurol. 2022 Oct 28;13:1026850. doi: 10.3389/fneur.2022.1026850. eCollection 2022. Front Neurol. 2022. PMID: 36388227 Free PMC article.
Future studies should investigate whether early rehabilitation programs started during the acute phase might help prevent or limit the development of secondary deformities....
Future studies should investigate whether early rehabilitation programs started during the acute phase might help prevent or limit th …
Oral anticoagulants: a systematic overview of reviews on efficacy and safety, genotyping, self-monitoring, and stakeholder experiences.
Khouja C, Brunton G, Richardson M, Stokes G, Blanchard L, Burchett H, Khatwa M, Walker R, Wright K, Sowden A, Thomas J. Khouja C, et al. Syst Rev. 2022 Oct 28;11(1):232. doi: 10.1186/s13643-022-02098-w. Syst Rev. 2022. PMID: 36303235 Free PMC article.
BACKGROUND: This systematic overview was commissioned by England's Department of Health and Social Care (DHSC) to assess the evidence on direct (previously 'novel') oral anticoagulants (OACs), compared with usual care, in adults, to prevent stroke related to atrial fibrill …
BACKGROUND: This systematic overview was commissioned by England's Department of Health and Social Care (DHSC) to assess the evidence on dir …
Interventional compared with medical management of symptomatic carotid web: A systematic review.
Patel SD, Otite FO, Topiwala K, Saber H, Kaneko N, Sussman E, Mehta TV, Tummala R, Hinman J, Nogueira R, Haussen DC, Liebeskind DS, Saver JL. Patel SD, et al. J Stroke Cerebrovasc Dis. 2022 Oct;31(10):106682. doi: 10.1016/j.jstrokecerebrovasdis.2022.106682. Epub 2022 Aug 20. J Stroke Cerebrovasc Dis. 2022. PMID: 35998383 Free article.
CONCLUSION: Cumulative evidence from multiple series suggests that carotid revascularization is a safe and effective option for preventing recurrent ischemic events in patients with symptomatic carotid webs....
CONCLUSION: Cumulative evidence from multiple series suggests that carotid revascularization is a safe and effective option for preventin
Diverging Temporal Trends in Stroke Incidence in Younger vs Older People: A Systematic Review and Meta-analysis.
Scott CA, Li L, Rothwell PM. Scott CA, et al. JAMA Neurol. 2022 Oct 1;79(10):1036-1048. doi: 10.1001/jamaneurol.2022.1520. JAMA Neurol. 2022. PMID: 35943738 Free PMC article.
CONCLUSIONS AND RELEVANCE: Temporal trends in stroke incidence are diverging by age in high-income countries, with less favorable trends at younger vs older ages, highlighting the urgent need to better understand etiology and prevention of stroke at younger ages....
CONCLUSIONS AND RELEVANCE: Temporal trends in stroke incidence are diverging by age in high-income countries, with less favorable trends at …
Effectiveness and Safety of Antithrombotic Medication in Patients With Atrial Fibrillation and Intracranial Hemorrhage: Systematic Review and Meta-Analysis.
Ivany E, Ritchie LA, Lip GYH, Lotto RR, Werring DJ, Lane DA. Ivany E, et al. Stroke. 2022 Oct;53(10):3035-3046. doi: 10.1161/STROKEAHA.122.038752. Epub 2022 Jul 8. Stroke. 2022. PMID: 35862238 Free PMC article.
Articles on adults with atrial fibrillation with spontaneous ICrH (intracerebral, subdural, and subarachnoid), receiving antithrombotic therapy for stroke prevention were eligible for inclusion. RESULTS: Twenty articles (50 470 participants) included 2 randomized controlle …
Articles on adults with atrial fibrillation with spontaneous ICrH (intracerebral, subdural, and subarachnoid), receiving antithrombotic ther …
Contemporary antiplatelet therapy for secondary stroke prevention: a narrative review of current literature and guidelines.
Shah J, Liu S, Yu W. Shah J, et al. Stroke Vasc Neurol. 2022 Oct;7(5):406-414. doi: 10.1136/svn-2021-001166. Epub 2022 Apr 7. Stroke Vasc Neurol. 2022. PMID: 35393359 Free PMC article.
Antiplatelet therapy is one of the mainstays for secondary stroke prevention. This narrative review aimed to highlight the current evidence and recommendations of antiplatelet therapy for stroke prevention.We conducted advanced literature search for antiplatelet the …
Antiplatelet therapy is one of the mainstays for secondary stroke prevention. This narrative review aimed to highlight the current ev …
Incidence of stroke in the first year after diagnosis of cancer-A systematic review and meta-analysis.
Lun R, Roy DC, Hao Y, Deka R, Huang WK, Navi BB, Siegal DM, Ramsay T, Fergusson D, Shorr R, Dowlatshahi D. Lun R, et al. Front Neurol. 2022 Sep 20;13:966190. doi: 10.3389/fneur.2022.966190. eCollection 2022. Front Neurol. 2022. PMID: 36203979 Free PMC article.
Cancer patients should be educated on the risk of stroke at the time of diagnosis. Future studies should evaluate optimal primary prevention strategies in this high-risk group of patients. SYSTEMATIC REVIEW REGISTRATION: https://osf.io/ucwy9/....
Cancer patients should be educated on the risk of stroke at the time of diagnosis. Future studies should evaluate optimal primary prevent
Transcranial direct current stimulation for gait recovery following stroke: A systematic review of current literature and beyond.
Corominas-Teruel X, Mozo RMSS, Simó MF, Colomina Fosch MT, Valero-Cabré A. Corominas-Teruel X, et al. Front Neurol. 2022 Sep 7;13:953939. doi: 10.3389/fneur.2022.953939. eCollection 2022. Front Neurol. 2022. PMID: 36158971 Free PMC article.
Even so, results are still inconsistent due to low sample size, heterogeneity of samples, and tDCS design differences preventing comparability. Nonetheless, updated knowledge in post-stroke neurophysiology and stimulation technologies opens up opportunities to massively im …
Even so, results are still inconsistent due to low sample size, heterogeneity of samples, and tDCS design differences preventing comp …
Probiotic as a Potential Gut Microbiome Modifier for Stroke Treatment: A Systematic Scoping Review of In Vitro and In Vivo Studies.
Savigamin C, Samuthpongtorn C, Mahakit N, Nopsopon T, Heath J, Pongpirul K. Savigamin C, et al. Nutrients. 2022 Sep 5;14(17):3661. doi: 10.3390/nu14173661. Nutrients. 2022. PMID: 36079918 Free PMC article. Review.
The initial screening criteria aimed to include studies using probiotics, prebiotics, and symbiotics both in vitro and in vivo for the prevention and/or treatment of stroke. RESULTS: Of 6293 articles, 4990 passed the initial screen after excluding duplication articles, of …
The initial screening criteria aimed to include studies using probiotics, prebiotics, and symbiotics both in vitro and in vivo for the pr
Systematic review and meta-analysis examining the relationship between postprandial hypotension, cardiovascular events, and all-cause mortality.
Jenkins DJA, Sahye-Pudaruth S, Khodabandehlou K, Liang F, Kasmani M, Wanyan J, Wang M, Selvaganesh K, Paquette M, Patel D, Glenn AJ, Srichaikul K, Kendall CWC, Sievenpiper JL. Jenkins DJA, et al. Am J Clin Nutr. 2022 Sep 2;116(3):663-671. doi: 10.1093/ajcn/nqac158. Am J Clin Nutr. 2022. PMID: 35675216 Free PMC article.
Hydroxyurea (hydroxycarbamide) for sickle cell disease.
Rankine-Mullings AE, Nevitt SJ. Rankine-Mullings AE, et al. Cochrane Database Syst Rev. 2022 Sep 1;9(9):CD002202. doi: 10.1002/14651858.CD002202.pub3. Cochrane Database Syst Rev. 2022. PMID: 36047926 Free PMC article. Review.
Hydroxyurea with phlebotomy probably increased HbF and decreased neutrophil counts (moderate-quality evidence), but there were more occurrences of acute chest syndrome and infections. Quality of life was not reported. In the primary prevention study, no strokes occurred in …
Hydroxyurea with phlebotomy probably increased HbF and decreased neutrophil counts (moderate-quality evidence), but there were more occurren …
A systematic review and meta-analysis for the primary prevention of high risk of stroke by Nao-an capsules.
Wang L, Fan X, Du W, Liang X, Chen Y, Shi J, Sun L, Shen W, Zhang Y. Wang L, et al. Phytomedicine. 2022 Sep;104:154263. doi: 10.1016/j.phymed.2022.154263. Epub 2022 Jun 15. Phytomedicine. 2022. PMID: 35772341 Free article. Review.
BACKGROUND: To date, Nao-an capsules are the only Chinese patent medicine primarily prescribed for the primary prevention of stroke. PURPOSE: To evaluate the efficacy and safety of Nao-an capsules in the primary prevention of stroke in high-risk patients. ...CONCLUS …
BACKGROUND: To date, Nao-an capsules are the only Chinese patent medicine primarily prescribed for the primary prevention of stroke. …
A Systematic Review and Meta-Analysis of the Associations between Immigration Status and Stroke Incidence and Mortality.
Chen JZ, Wang HM, Zhu W. Chen JZ, et al. Biomed Res Int. 2022 Aug 26;2022:1926744. doi: 10.1155/2022/1926744. eCollection 2022. Biomed Res Int. 2022. PMID: 36060129 Free PMC article. Review.
The present systematic review and meta-analysis implicated that stroke risks are different for immigrants and the host populations; therefore, this knowledge may be useful for developing targeted stroke prevention strategies....
The present systematic review and meta-analysis implicated that stroke risks are different for immigrants and the host populations; therefor …
The effect of omega-3 polyunsaturated fatty acids on stroke treatment and prevention: a systematic review and meta-analysis.
Xu Q, Du L, Gu H, Ji M, Zhan L. Xu Q, et al. Nutr Hosp. 2022 Aug 25;39(4):924-935. doi: 10.20960/nh.04148. Nutr Hosp. 2022. PMID: 35916137 Free article. English.
After the oral administration of n-3 PUFAs, the levels of TC and TG decreased significantly, but n-3 PUFAs did not prevent the occurrence of cerebrovascular accidents or improve LDL or HDL levels....
After the oral administration of n-3 PUFAs, the levels of TC and TG decreased significantly, but n-3 PUFAs did not prevent the occurr …
Antithrombotic therapy for secondary prevention in patients with stroke or transient ischemic attack: A multiple treatment network meta-analysis of randomized controlled trials.
Tornyos D, Komócsi A, Bálint A, Kupó P, El Abdallaoui OEA, Szapáry L, Szapáry LB. Tornyos D, et al. PLoS One. 2022 Aug 17;17(8):e0273103. doi: 10.1371/journal.pone.0273103. eCollection 2022. PLoS One. 2022. PMID: 35976963 Free PMC article.
OBJECTIVE: As stroke represents one of the leading causes of mortality and disability worldwide, we aimed to determine the preventive effect of different antiplatelet therapies after an ischemic stroke or transient ischemic attack. ...
OBJECTIVE: As stroke represents one of the leading causes of mortality and disability worldwide, we aimed to determine the preventive
Guideline Adherence As An Indicator of the Extent of Antithrombotic Overuse and Underuse: A Systematic Review.
Cardona M, Craig L, Jones M, Byambasuren O, Obucina M, Hattingh L, Clark J, Glasziou P, Hoffmann T. Cardona M, et al. Glob Heart. 2022 Aug 12;17(1):55. doi: 10.5334/gh.1142. eCollection 2022. Glob Heart. 2022. PMID: 36051325 Free PMC article. Review.
The objective of this review was to investigate the extent of overuse and underuse of antithrombotics for primary or secondary prevention as measured by deviation from prescribing guideline recommendations. ...
The objective of this review was to investigate the extent of overuse and underuse of antithrombotics for primary or secondary prevention
Prevalence and risk factors of ischemic stroke-related headache in China: a systematic review and meta-analysis.
Xie Q, Wu Y, Pei J, Gao Q, Guo Q, Wang X, Zhong J, Su Y, Zhao J, Zhang L, Dou X. Xie Q, et al. BMC Public Health. 2022 Aug 11;22(1):1533. doi: 10.1186/s12889-022-13917-z. BMC Public Health. 2022. PMID: 35953857 Free PMC article.
In addition, women, presence of midbrain lesions, posterior circulation stroke and a history of migraine were high-risk factors for ischemic stroke-related headaches. Designing effective interventions to prevent or alleviated headaches is necessary to promote patients' neu …
In addition, women, presence of midbrain lesions, posterior circulation stroke and a history of migraine were high-risk factors for ischemic …
A Systematic Review of Fall Risk Factors in Stroke Survivors: Towards Improved Assessment Platforms and Protocols.
Abdollahi M, Whitton N, Zand R, Dombovy M, Parnianpour M, Khalaf K, Rashedi E. Abdollahi M, et al. Front Bioeng Biotechnol. 2022 Aug 8;10:910698. doi: 10.3389/fbioe.2022.910698. eCollection 2022. Front Bioeng Biotechnol. 2022. PMID: 36003532 Free PMC article.
Background/Purpose: To prevent falling, a common incident with debilitating health consequences among stroke survivors, it is important to identify significant fall risk factors (FRFs) towards developing and implementing predictive and preventive strategies and guid …
Background/Purpose: To prevent falling, a common incident with debilitating health consequences among stroke survivors, it is importa …
Smoking cessation for secondary prevention of cardiovascular disease.
Wu AD, Lindson N, Hartmann-Boyce J, Wahedi A, Hajizadeh A, Theodoulou A, Thomas ET, Lee C, Aveyard P. Wu AD, et al. Cochrane Database Syst Rev. 2022 Aug 8;8(8):CD014936. doi: 10.1002/14651858.CD014936.pub2. Cochrane Database Syst Rev. 2022. PMID: 35938889 Free PMC article. Review.
BACKGROUND: Smoking is a leading cause of cardiovascular disease (CVD), particularly coronary heart disease (CHD). However, quitting smoking may prevent secondary CVD events in people already diagnosed with CHD. ...Additional studies that account for confounding, such as u …
BACKGROUND: Smoking is a leading cause of cardiovascular disease (CVD), particularly coronary heart disease (CHD). However, quitting smoking …
Economic evaluation of direct oral anticoagulants (DOACs) versus vitamin K antagonists (VKAs) for stroke prevention in patients with atrial fibrillation: a systematic review and meta-analysis.
Noviyani R, Youngkong S, Nathisuwan S, Bagepally BS, Chaikledkaew U, Chaiyakunapruk N, McKay G, Sritara P, Attia J, Thakkinstian A. Noviyani R, et al. BMJ Evid Based Med. 2022 Aug;27(4):215-223. doi: 10.1136/bmjebm-2020-111634. Epub 2021 Oct 11. BMJ Evid Based Med. 2022. PMID: 34635480 Free PMC article.
OBJECTIVES: To assess cost-effectiveness of direct oral anticoagulants (DOACs) compared with vitamin K antagonists (VKAs) for stroke prevention in atrial fibrillation (AF) by pooling incremental net benefits (INBs). ...
OBJECTIVES: To assess cost-effectiveness of direct oral anticoagulants (DOACs) compared with vitamin K antagonists (VKAs) for stroke prev
Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without dementia.
Kwan J, Hafdi M, Chiang LLW, Myint PK, Wong LS, Quinn TJ. Kwan J, et al. Cochrane Database Syst Rev. 2022 Jul 14;7(7):CD012269. doi: 10.1002/14651858.CD012269.pub2. Cochrane Database Syst Rev. 2022. PMID: 35833913 Free PMC article. Review.
As antithrombotic therapy is an established treatment for stroke prevention, we sought to determine whether antithrombotic therapy might also be effective in preventing cognitive decline in people with small vessel disease. OBJECTIVES: To assess the effects of antit …
As antithrombotic therapy is an established treatment for stroke prevention, we sought to determine whether antithrombotic therapy mi …
The role of CYP2C19 genotyping to guide antiplatelet therapy following ischemic stroke or transient ischemic attack.
McDermott JH, Leach M, Sen D, Smith CJ, Newman WG, Bath PM. McDermott JH, et al. Expert Rev Clin Pharmacol. 2022 Jul;15(7):811-825. doi: 10.1080/17512433.2022.2108401. Epub 2022 Aug 4. Expert Rev Clin Pharmacol. 2022. PMID: 35912831 Free PMC article.
INTRODUCTION: Clopidogrel is an antiplatelet agent recommended for secondary prevention of ischemic stroke (IS) and transient ischemic attack (TIA). ...The expansion of pharmacogenetics into routine clinical practice will facilitate further research and help tailor other a …
INTRODUCTION: Clopidogrel is an antiplatelet agent recommended for secondary prevention of ischemic stroke (IS) and transient ischemi …
The Role of Non-Vitamin K Antagonist Oral Anticoagulants (NOACs) in Atrial Fibrillation: Treatment Management Based on Patient and Drug Characteristics.
Ergene O, Aras D, Kaymaz C, Arsava EM, Gönen C, Gürkaş E, Arslan U, Çağırıcı G, Çay S, Kılıçkap M, Kanat S, Özpelit E, Vatansever F, Kılıçkesmez K. Ergene O, et al. Turk Kardiyol Dern Ars. 2022 Jul;50(5):356-370. doi: 10.5543/tkda.2022.21191. Turk Kardiyol Dern Ars. 2022. PMID: 35860888 Free article.
Effectiveness of kinesiology taping on the functions of upper limbs in patients with stroke: a meta-analysis of randomized trial.
Wang Y, Li X, Sun C, Xu R. Wang Y, et al. Neurol Sci. 2022 Jul;43(7):4145-4156. doi: 10.1007/s10072-022-06010-1. Epub 2022 Mar 26. Neurol Sci. 2022. PMID: 35347525 Free PMC article. Review.
BACKGROUND: Kinesiology tape (KT), a water-resistant and elastic tape which is well known measure for preventing musculoskeletal injuries, has recently gained popularity in neurological rehabilitation. ...
BACKGROUND: Kinesiology tape (KT), a water-resistant and elastic tape which is well known measure for preventing musculoskeletal inju …
Effects of control strategies on gait in robot-assisted post-stroke lower limb rehabilitation: a systematic review.
Campagnini S, Liuzzi P, Mannini A, Riener R, Carrozza MC. Campagnini S, et al. J Neuroeng Rehabil. 2022 Jun 3;19(1):52. doi: 10.1186/s12984-022-01031-5. J Neuroeng Rehabil. 2022. PMID: 35659703 Free PMC article.
The heterogeneity of performance assessment, study designs and patients' numerosity prevented the possibility to conduct a rigorous meta-analysis, thus, the results were presented through narrative synthesis. ...
The heterogeneity of performance assessment, study designs and patients' numerosity prevented the possibility to conduct a rigorous m …
Machine learning methods for functional recovery prediction and prognosis in post-stroke rehabilitation: a systematic review.
Campagnini S, Arienti C, Patrini M, Liuzzi P, Mannini A, Carrozza MC. Campagnini S, et al. J Neuroeng Rehabil. 2022 Jun 3;19(1):54. doi: 10.1186/s12984-022-01032-4. J Neuroeng Rehabil. 2022. PMID: 35659246 Free PMC article. Review.
CONCLUSIONS: We identified several methodological limitations: small sample sizes, a limited number of external validation approaches, and high heterogeneity among input and output variables. Although these elements prevented a quantitative comparison across models, we def …
CONCLUSIONS: We identified several methodological limitations: small sample sizes, a limited number of external validation approaches, and h …