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77 results

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Page 1
Driver lines for studying associative learning in Drosophila.
Shuai Y, Sammons M, Sterne GR, Hibbard KL, Yang H, Yang CP, Managan C, Siwanowicz I, Lee T, Rubin GM, Turner GC, Aso Y. Shuai Y, et al. Among authors: lee t. Elife. 2025 Jan 29;13:RP94168. doi: 10.7554/eLife.94168. Elife. 2025. PMID: 39879130 Free PMC article.
The mushroom body (MB) is the center for associative learning in insects. In Drosophila, intersectional split-GAL4 drivers and electron microscopy (EM) connectomes have laid the foundation for precise interrogation of the MB neural circuits. ...In conjunction with the EM c …
The mushroom body (MB) is the center for associative learning in insects. In Drosophila, intersectional split-GAL4 drivers and electr …
Lineage Analysis at Single-Cell Resolution by Twin-Spot MARCM with Lineage-Restricted Drivers.
Previero A, Yang CP, Lee T. Previero A, et al. Among authors: lee t. Methods Mol Biol. 2025;2886:401-420. doi: 10.1007/978-1-0716-4310-5_20. Methods Mol Biol. 2025. PMID: 39745652
The power of twin-spot MARCM to systematically subdivide complex lineages is exemplified in studies of Drosophila neural stem-cell lineages. To achieve targeted lineage analysis, lineage-restricted drivers can be created by restricting and immortalizing gene expression to …
The power of twin-spot MARCM to systematically subdivide complex lineages is exemplified in studies of Drosophila neural stem-cell li …
Metamorphosis of memory circuits in Drosophila reveals a strategy for evolving a larval brain.
Truman JW, Price J, Miyares RL, Lee T. Truman JW, et al. Among authors: lee t. Elife. 2023 Jan 25;12:e80594. doi: 10.7554/eLife.80594. Elife. 2023. PMID: 36695420 Free PMC article.
Mushroom bodies (MB) of adult Drosophila have a core of thousands of Kenyon neurons; axons of the early-born g class form a medial lobe and those from later-born alpha'beta' and alphabeta classes form both medial and vertical lobes. ...
Mushroom bodies (MB) of adult Drosophila have a core of thousands of Kenyon neurons; axons of the early-born g class form a medial lo …
Tracing and Manipulating Drosophila Cell Lineages Based on CRISPR: CaSSA and CLADES.
Garcia-Marques J, Lee T. Garcia-Marques J, et al. Among authors: lee t. Methods Mol Biol. 2022;2540:201-217. doi: 10.1007/978-1-0716-2541-5_9. Methods Mol Biol. 2022. PMID: 35980579
Here we discuss how to better exploit this technology for lineage studies in Drosophila, with an emphasis on neuronal specification....
Here we discuss how to better exploit this technology for lineage studies in Drosophila, with an emphasis on neuronal specification.. …
The art of lineage tracing: From worm to human.
Garcia-Marques J, Espinosa-Medina I, Lee T. Garcia-Marques J, et al. Among authors: lee t. Prog Neurobiol. 2021 Apr;199:101966. doi: 10.1016/j.pneurobio.2020.101966. Epub 2020 Nov 26. Prog Neurobiol. 2021. PMID: 33249090 Review.
A programmable sequence of reporters for lineage analysis.
Garcia-Marques J, Espinosa-Medina I, Ku KY, Yang CP, Koyama M, Yu HH, Lee T. Garcia-Marques J, et al. Among authors: lee t. Nat Neurosci. 2020 Dec;23(12):1618-1628. doi: 10.1038/s41593-020-0676-9. Epub 2020 Jul 27. Nat Neurosci. 2020. PMID: 32719561
Enhanced Golic+: highly effective CRISPR gene targeting and transgene HACKing in Drosophila.
Chen HM, Yao X, Ren Q, Chang CC, Liu LY, Miyares RL, Lee T. Chen HM, et al. Among authors: lee t. Development. 2020 Jun 11;147(11):dev181974. doi: 10.1242/dev.181974. Development. 2020. PMID: 32467238
To bypass these barriers, we designed a transgene-based system in Drosophila that increases the number of independent gene targeting events while at the same time enriching for correctly targeted progeny. ...Given the superior efficiency, specificity and scalability, E-Gol …
To bypass these barriers, we designed a transgene-based system in Drosophila that increases the number of independent gene targeting …
77 results