Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2022 1
2023 8
2024 11
2025 2

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

18 results

Results by year

Filters applied: . Clear all
Page 1
Comprehensive analysis of the function of helicobacter-associated ferroptosis gene YWHAE in gastric cancer through multi-omics integration, molecular docking, and machine learning.
Liu D, Peng J, Xie J, Xie Y. Liu D, et al. Apoptosis. 2024 Apr;29(3-4):439-456. doi: 10.1007/s10495-023-01916-3. Epub 2023 Nov 24. Apoptosis. 2024. PMID: 38001345
Pan-cancer analysis revealed elevated expression of YWHAE in several cancer types compared to normal tissues. We also examined the methylation, single nucleotide variations (SNVs), and copy number variations (CNVs) associated with YWHAE. ...Finally, qRT-PCR and immu …
Pan-cancer analysis revealed elevated expression of YWHAE in several cancer types compared to normal tissues. We also examined the me …
14-3-3epsilon/YWHAE regulates the transcriptional expression of cardiac sodium channel Na(V)1.5.
Hu Y, Zhang C, Wang S, Xiong H, Xie W, Zeng Z, Cai H, Wang QK, Lu Z. Hu Y, et al. Heart Rhythm. 2024 Nov;21(11):2320-2329. doi: 10.1016/j.hrthm.2024.05.015. Epub 2024 May 13. Heart Rhythm. 2024. PMID: 38750908
An interaction between 14-3-3epsilon protein and TBX5 mRNA was identified, and YWHAE overexpression significantly decreased TBX5 mRNA stability without affecting SCN5A mRNA stability. In addition, mice subjected to adeno-associated virus serotype 9-mediated YWHAE kn …
An interaction between 14-3-3epsilon protein and TBX5 mRNA was identified, and YWHAE overexpression significantly decreased TBX5 mRNA …
SPI1-mediated MIR222HG transcription promotes proneural-to-mesenchymal transition of glioma stem cells and immunosuppressive polarization of macrophages.
Fan Y, Gao Z, Xu J, Wang H, Guo Q, Li B, Li M, Xu H, Qi Y, Zhao S, Qiu W, Pan Z, Wang Q, Xue H, Zhao R, Guo X, Li G. Fan Y, et al. Theranostics. 2023 May 27;13(10):3310-3329. doi: 10.7150/thno.82590. eCollection 2023. Theranostics. 2023. PMID: 37351164 Free PMC article.
Mechanistically, MIR222HG can bind to the YWHAE/HDAC5 complex to promote the MES transition of GSCs through H4 deacetylation. Moreover, cotranscribed miR221 and miR222 can be delivered to macrophages via exosomes to target SOCS3, causing immunosuppressive polarization. ...
Mechanistically, MIR222HG can bind to the YWHAE/HDAC5 complex to promote the MES transition of GSCs through H4 deacetylation. Moreove …
Circular RNA AGFG1 motivates breast cancer cell proliferation, invasion, migration, and glycolysis by controlling microRNA-653-5p/14-3-3 protein epsilon.
Chen L, Qian J, Shen Y, Yu X. Chen L, et al. Acta Biochim Pol. 2023 Oct 18;70(4):777-784. doi: 10.18388/abp.2020_6254. Acta Biochim Pol. 2023. PMID: 37851953 Free article.
A nude mouse xenograft experiment was performed to verify the effect of circAGFG1 on cancer cells in vivo. The results showed that circAGFG1 and YWHAE were highly expressed in BC while miR-653-5p was lowly expressed. Both circAGFG1 and YWHAE had a targeting relation …
A nude mouse xenograft experiment was performed to verify the effect of circAGFG1 on cancer cells in vivo. The results showed that circAGFG1 …
A Case of Class I 17p13.3 Microduplication Syndrome with Unilateral Hearing Loss.
Vittas S, Bisba M, Christopoulou G, Apostolakopoulou L, Pons R, Constantoulakis P. Vittas S, et al. Genes (Basel). 2023 Jun 24;14(7):1333. doi: 10.3390/genes14071333. Genes (Basel). 2023. PMID: 37510238 Free PMC article.
Critical genes for this region are PAFAH1B1 (#601545), YWHAE (#605066), and CRK (#164762). 17p13.3 microduplication syndrome can be categorized into two classes (Class I and Class II) based on the genes that are present in the duplicated area, which lead to different pheno …
Critical genes for this region are PAFAH1B1 (#601545), YWHAE (#605066), and CRK (#164762). 17p13.3 microduplication syndrome can be c …
Exploratory research on genetic polymorphisms associated with positive empathy and trait forgivingness among the Japanese.
Matsunaga M, Ohtsubo Y, Masuda T, Noguchi Y, Yamasue H, Ishii K. Matsunaga M, et al. Neuro Endocrinol Lett. 2023 Dec 12;44(8):506-516. Neuro Endocrinol Lett. 2023. PMID: 38131174
In addition, genetic polymorphisms in the 5-hydroxytryptamine (serotonin) receptor 7 (HTR7: rs77843021) and tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon (YWHAE: rs9908013), which are associated with dopamine and serotonin biosynthesis, ar …
In addition, genetic polymorphisms in the 5-hydroxytryptamine (serotonin) receptor 7 (HTR7: rs77843021) and tyrosine 3-monooxygenase/tryptop …
Genomic and Transcriptomic Characterization Revealed the High Sensitivity of Targeted Therapy and Immunotherapy in a Subset of Endometrial Stromal Sarcoma.
Kang N, Zhang Y, Guo S, Chen R, Kong F, Wang S, Yuan M, Chen R, Shen D, Wang J. Kang N, et al. Cancer Res Treat. 2023 Jul;55(3):978-991. doi: 10.4143/crt.2022.1647. Epub 2023 Feb 2. Cancer Res Treat. 2023. PMID: 36731460 Free PMC article.
The classical fusions frequently found in HGESS (ZC3H7B-BCOR and NUTM2B-YWHAE) and LGESS (JAZF1-SUZ12) were detected in our cohort. CCND1 was significantly up-regulated in HGESS, while the expression of GPER1 and PGR encoding estrogen receptor (ER) and progesterone recepto …
The classical fusions frequently found in HGESS (ZC3H7B-BCOR and NUTM2B-YWHAE) and LGESS (JAZF1-SUZ12) were detected in our cohort. C …
Identification and validation of iron metabolism genes in osteoporosis.
Li Z, Xu J, Shi S, Weng Y, Guo B, Che L, Sun J. Li Z, et al. BMC Med Genomics. 2024 Jan 2;17(1):5. doi: 10.1186/s12920-023-01779-2. BMC Med Genomics. 2024. PMID: 38169377 Free PMC article.
The PPI network contained 12 differentially expressed iron metabolism-related genes. Additionally, YWHAE, TGFB1, PPP1R15A, TOP2A, and CALR were mined as hub genes using the Cytoscape software. qRT PCR showed that the expression of TGF-beta1, YWHAE, TOP2A and CALR in …
The PPI network contained 12 differentially expressed iron metabolism-related genes. Additionally, YWHAE, TGFB1, PPP1R15A, TOP2A, and …
Uncommon Protein-Coding Variants Associated With Suicide Attempt in a Diverse Sample of U.S. Army Soldiers.
Wilkerson MD, Hupalo D, Gray JC, Zhang X, Wang J, Girgenti MJ, Alba C, Sukumar G, Lott NM, Naifeh JA, Aliaga P, Kessler RC, Turner C, Pollard HB, Dalgard CL, Ursano RJ, Stein MB. Wilkerson MD, et al. Biol Psychiatry. 2024 Jul 1;96(1):15-25. doi: 10.1016/j.biopsych.2023.12.008. Epub 2023 Dec 21. Biol Psychiatry. 2024. PMID: 38141912 Free article.

RESULTS: We identified 19 genes with variants enriched in individuals with history of suicide attempt, either through gene-collapsed or single-variant analysis (Bonferroni p(adjusted) < .05). These genes were CIB2, MLF1, HERC1, YWHAE, RCN2, VWA5B1, ATAD3A, NACA, EP400,

…
RESULTS: We identified 19 genes with variants enriched in individuals with history of suicide attempt, either through gene-collapsed or sing …
circSORBS1 inhibits lung cancer progression by sponging miR-6779-5p and directly binding RUFY3 mRNA.
Xu H, Zheng Y, Wu J, Zhang R, Zhao Q, Chen S, Peng W, Cai D, Gao Y, Chen X, Li D, Yuan S, Li G, Nan A. Xu H, et al. J Transl Med. 2024 Jun 24;22(1):590. doi: 10.1186/s12967-024-05423-0. J Transl Med. 2024. PMID: 38915053 Free PMC article.
This dual regulatory mechanism leads to an increase in RUFY3 protein levels, which ultimately activates the YWHAE/BAD/BCL2 apoptotic signalling pathway and suppresses lung cancer progression. Our findings not only increase the knowledge about the regulatory pattern of circ …
This dual regulatory mechanism leads to an increase in RUFY3 protein levels, which ultimately activates the YWHAE/BAD/BCL2 apoptotic …
18 results