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Year Number of Results
2019 5
2020 24
2021 26
2022 12
2023 16
2024 13

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87 results

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Page 1
Clinical Features and Genetic Analysis of Taiwanese Primary Immunodeficiency Patients with Prolonged Diarrhea and Monogenetic Inflammatory Bowel Disease.
Lee WI, Chen CC, Chen SH, Lai WT, Jaing TH, Ou LS, Liang CJ, Kang CC, Huang JL. Lee WI, et al. J Clin Immunol. 2023 Aug;43(6):1455-1467. doi: 10.1007/s10875-023-01503-w. Epub 2023 May 19. J Clin Immunol. 2023. PMID: 37202577
In the mono-IBD group, seventeen patients with mutant TTC7A (2), FOXP3 (2), NEMO (2), XIAP (2), LRBA (1), TTC37 (3), IL10RA (1), STAT1 (1), ZAP70 (1), PIK3CD (1), and PIK3R1 (1) genes failed to respond to aggressive treatments. ...
In the mono-IBD group, seventeen patients with mutant TTC7A (2), FOXP3 (2), NEMO (2), XIAP (2), LRBA (1), TTC37 (3), IL10RA (1), STAT1 (1), …
The role of competing mechanisms on Lck regulation.
Bozso SJ, Kang JJH, Nagendran J. Bozso SJ, et al. Immunol Res. 2020 Oct;68(5):289-295. doi: 10.1007/s12026-020-09148-2. Epub 2020 Aug 14. Immunol Res. 2020. PMID: 32794043 Review.
Biomarker prediction in autism spectrum disorder using a network-based approach.
Rastegari M, Salehi N, Zare-Mirakabad F. Rastegari M, et al. BMC Med Genomics. 2023 Jan 23;16(1):12. doi: 10.1186/s12920-023-01439-5. BMC Med Genomics. 2023. PMID: 36691005 Free PMC article.
RESULTS: In the first step of the framework, the FA_gene algorithm finds a set of important genes; TP53, TNF, MAPK3, ACTB, TLR7, LCK, RAC2, EEF2, CAT, ZAP70, CD19, RPLP0, CDKN1A, CCL2, CDK4, CCL5, CTSD, CD4, RACK1, CD74; using co-expression and protein-protein interaction …
RESULTS: In the first step of the framework, the FA_gene algorithm finds a set of important genes; TP53, TNF, MAPK3, ACTB, TLR7, LCK, RAC2, …
Ablation of SYK Kinase from Expanded Primary Human NK Cells via CRISPR/Cas9 Enhances Cytotoxicity and Cytokine Production.
Dahlvang JD, Dick JK, Sangala JA, Kennedy PR, Pomeroy EJ, Snyder KM, Moushon JM, Thefaine CE, Wu J, Hamilton SE, Felices M, Miller JS, Walcheck B, Webber BR, Moriarity BS, Hart GT. Dahlvang JD, et al. J Immunol. 2023 Apr 15;210(8):1108-1122. doi: 10.4049/jimmunol.2200488. J Immunol. 2023. PMID: 36881874 Free PMC article.
We ablated genes that encode molecules in the ADCC pathway, such as FcRgamma, CD3zeta, SYK, SHP-1, ZAP70, and the transcription factor PLZF, and tested subsequent ADCC and cytokine production. ...Importantly, SYK kinase ablation significantly enhanced cytotoxicity, cytokin …
We ablated genes that encode molecules in the ADCC pathway, such as FcRgamma, CD3zeta, SYK, SHP-1, ZAP70, and the transcription facto …
New insights into the genetic predisposition of brucellosis and its effect on the gut and vaginal microbiota in goats.
Sallam AM, Abou-Souliman I, Reyer H, Wimmers K, Rabee AE. Sallam AM, et al. Sci Rep. 2023 Nov 16;13(1):20086. doi: 10.1038/s41598-023-46997-x. Sci Rep. 2023. PMID: 37973848 Free PMC article.
Corresponding markers were located within or in close vicinity to several candidate genes, such as ARRB1, RELT, ATG16L2, IGSF21, UBR4, ULK1, DCN, MAPB1, NAIP, CD26, IFIH1, NDFIP2, DOK4, MAF, IL2RB, USP18, ARID5A, ZAP70, CNTN5, PIK3AP1, DNTT, BLNK, and NHLRC3. These genes p …
Corresponding markers were located within or in close vicinity to several candidate genes, such as ARRB1, RELT, ATG16L2, IGSF21, UBR4, ULK1, …
Identification of important genes related to anoikis in acute myocardial infarction.
Song P, Yakufujiang Y, Zhou J, Gu S, Wang W, Huo Z. Song P, et al. J Cell Mol Med. 2024 Apr;28(8):e18264. doi: 10.1111/jcmm.18264. J Cell Mol Med. 2024. PMID: 38526027 Free PMC article.
PPI network analysis was also conducted, and 10 hub genes, such as IL1B, ZAP70, LCK, FASLG, CD4, LRP1, CDH2, MERTK, APOE and VTN were identified. ...
PPI network analysis was also conducted, and 10 hub genes, such as IL1B, ZAP70, LCK, FASLG, CD4, LRP1, CDH2, MERTK, APOE and VTN were …
Landscape of NOTCH1 mutations and co-occurring biomarker alterations in chronic lymphocytic leukemia.
Jelloul FZ, Yang R, Garces S, Kanagal-Shamanna R, Ok CY, Loghavi S, Routbort MJ, Zuo Z, Yin CC, Floyd K, Bassett RL, Wierda W, Jain N, Thompson P, Luthra R, Medeiros LJ, Patel KP. Jelloul FZ, et al. Leuk Res. 2022 May;116:106827. doi: 10.1016/j.leukres.2022.106827. Epub 2022 Mar 21. Leuk Res. 2022. PMID: 35430388 Free PMC article.
NOTCH1 mutations were more commonly seen in patients with unmutated IGHV, ZAP70 positivity and CD38 positivity. Mixed NOTCH1 mutations were also more commonly seen in patients with unmutated IGHV and ZAP70. ...
NOTCH1 mutations were more commonly seen in patients with unmutated IGHV, ZAP70 positivity and CD38 positivity. Mixed NOTCH1 mutation …
Natural isoaspartyl protein modification of ZAP70 alters T cell responses in lupus.
Yang ML, Lam TT, Kanyo J, Kang I, Zhou ZS, Clarke SG, Mamula MJ. Yang ML, et al. Autoimmunity. 2023 Dec;56(1):2282945. doi: 10.1080/08916934.2023.2282945. Epub 2023 Nov 23. Autoimmunity. 2023. PMID: 37994408 Free article.
Herein, we demonstrate that isoAsp modifications arise within the ZAP70 protein tyrosine kinase upon T-cell antigen receptor (TCR) engagement. ...Our studies reveal a phenotypic role of isoAsp modification and phosphorylation of ZAP70 in lupus T cell autoimmunity an …
Herein, we demonstrate that isoAsp modifications arise within the ZAP70 protein tyrosine kinase upon T-cell antigen receptor (TCR) en …
87 results