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1,570 results

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Page 1
Cerebral Cavernous Malformation: From Mechanism to Therapy.
Snellings DA, Hong CC, Ren AA, Lopez-Ramirez MA, Girard R, Srinath A, Marchuk DA, Ginsberg MH, Awad IA, Kahn ML. Snellings DA, et al. Circ Res. 2021 Jun 25;129(1):195-215. doi: 10.1161/CIRCRESAHA.121.318174. Epub 2021 Jun 24. Circ Res. 2021. PMID: 34166073 Free PMC article. Review.
Cerebral cavernous malformations are acquired vascular anomalies that constitute a common cause of central nervous system hemorrhage and stroke. ...This review addresses the genetic and molecular underpinnings of cerebral cavernous malformation disease …
Cerebral cavernous malformations are acquired vascular anomalies that constitute a common cause of central nervous system hemo …
Cerebral cavernous malformations - An overview on genetics, clinical aspects and therapeutic strategies.
Dulamea AO, Lupescu IC. Dulamea AO, et al. J Neurol Sci. 2024 Jun 15;461:123044. doi: 10.1016/j.jns.2024.123044. Epub 2024 May 12. J Neurol Sci. 2024. PMID: 38749279 Free article. Review.
Cerebral cavernous malformations (CCMs) are abnormally packed blood vessels lined with endothelial cells, that do not exhibit intervening tight junctions, lack muscular and elastic layers and are usually surrounded by hemosiderin and gliosis. ...The pathophysiology …
Cerebral cavernous malformations (CCMs) are abnormally packed blood vessels lined with endothelial cells, that do not exhibit …
PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism.
Ren AA, Snellings DA, Su YS, Hong CC, Castro M, Tang AT, Detter MR, Hobson N, Girard R, Romanos S, Lightle R, Moore T, Shenkar R, Benavides C, Beaman MM, Müller-Fielitz H, Chen M, Mericko P, Yang J, Sung DC, Lawton MT, Ruppert JM, Schwaninger M, Körbelin J, Potente M, Awad IA, Marchuk DA, Kahn ML. Ren AA, et al. Nature. 2021 Jun;594(7862):271-276. doi: 10.1038/s41586-021-03562-8. Epub 2021 Apr 28. Nature. 2021. PMID: 33910229 Free PMC article.
Vascular malformations are thought to be monogenic disorders that result in dysregulated growth of blood vessels. In the brain, cerebral cavernous malformations (CCMs) arise owing to inactivation of the endothelial CCM protein complex, which is require …
Vascular malformations are thought to be monogenic disorders that result in dysregulated growth of blood vessels. In the brain …
[Cerebral cavernous malformations].
Koht J, Braathen GJ, Neubert D, Russell MB. Koht J, et al. Tidsskr Nor Laegeforen. 2005 Aug 11;125(15):2008-10. Tidsskr Nor Laegeforen. 2005. PMID: 16100539 Free article. Review. Norwegian.
BACKGROUND: Cerebral cavernous malformations exist in sporadic and familial forms. They have considerable genetic and clinical heterogeneity. ...MATERIAL AND METHODS: This review is based on personal experience and recent literature. RESULTS: Cerebral caverno …
BACKGROUND: Cerebral cavernous malformations exist in sporadic and familial forms. They have considerable genetic and clinical …
Pediatric Cerebral Cavernous Malformations.
Paddock M, Lanham S, Gill K, Sinha S, Connolly DJA. Paddock M, et al. Pediatr Neurol. 2021 Mar;116:74-83. doi: 10.1016/j.pediatrneurol.2020.11.004. Epub 2020 Nov 27. Pediatr Neurol. 2021. PMID: 33494000 Review.
Cerebral cavernous malformations are the second most common vascular malformations in the central nervous system, and over one-third are found in children. ...Children may present with focal seizures, intracranial hemorrhage, or focal neurological deficits wi …
Cerebral cavernous malformations are the second most common vascular malformations in the central nervous system, and o …
Cerebral Cavernous Malformations.
Caton MT, Karsonovich T, Shenoy VS. Caton MT, et al. 2025 Jan 21. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. 2025 Jan 21. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. PMID: 30844171 Free Books & Documents.
Cerebral cavernous malformations (CCMs) are abnormally large collections of "low flow" vascular channels without brain parenchyma intervening between the sinusoidal vessels (see Images. Pons Cavernoma, Head CT, Cavernous Malformation). McCormick (1966) …
Cerebral cavernous malformations (CCMs) are abnormally large collections of "low flow" vascular channels without brain …
Familial Cerebral Cavernous Malformations.
Zafar A, Quadri SA, Farooqui M, Ikram A, Robinson M, Hart BL, Mabray MC, Vigil C, Tang AT, Kahn ML, Yonas H, Lawton MT, Kim H, Morrison L. Zafar A, et al. Stroke. 2019 May;50(5):1294-1301. doi: 10.1161/STROKEAHA.118.022314. Stroke. 2019. PMID: 30909834 Free PMC article. Review. No abstract available.
Editorial: Cerebral cavernous malformations.
Zuurbier SM, Santos AN, Flemming KD, Lanzino G, Dammann P, Heldner MR. Zuurbier SM, et al. Front Neurol. 2025 Sep 17;16:1687562. doi: 10.3389/fneur.2025.1687562. eCollection 2025. Front Neurol. 2025. PMID: 41041683 Free PMC article. No abstract available.
Circulating biomarkers in familial cerebral cavernous malformation.
Lazzaroni F, Meessen JMTA, Sun Y, Lanfranconi S, Scola E, D'Alessandris QG, Tassi L, Carriero MR, Castori M, Marino S, Blanda A, Nicolis EB, Novelli D, Calabrese R, Agnelli NM, Bottazzi B, Leone R, Mazzola S, Besana S, Catozzi C, Nezi L, Lampugnani MG, Malinverno M, Grdseloff N, Rödel CJ, Rezai Jahromi B, Bolli N, Passamonti F, Magnusson PU, Abdelilah-Seyfried S, Dejana E, Latini R. Lazzaroni F, et al. EBioMedicine. 2024 Jan;99:104914. doi: 10.1016/j.ebiom.2023.104914. Epub 2023 Dec 18. EBioMedicine. 2024. PMID: 38113759 Free PMC article.
BACKGROUND: Cerebral Cavernous Malformation (CCM) is a rare cerebrovascular disease, characterized by the presence of multiple vascular malformations that may result in intracerebral hemorrhages (ICHs), seizure(s), or focal neurological deficits (FND). ...
BACKGROUND: Cerebral Cavernous Malformation (CCM) is a rare cerebrovascular disease, characterized by the presence of multiple …
Familial Cerebral Cavernous Malformations.
Flemming KD, Smith E, Marchuk D, Derry WB. Flemming KD, et al. 2003 Feb 24 [updated 2023 Jul 27]. In: Adam MP, Bick S, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2026. 2003 Feb 24 [updated 2023 Jul 27]. In: Adam MP, Bick S, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2026. PMID: 20301470 Free Books & Documents. Review.
CLINICAL CHARACTERISTICS: Familial cerebral cavernous malformations (FCCM) is a disorder characterized by multiple vascular lesions in the brain and spinal cord that consist of clustered, endothelial-lined caverns ranging in diameter from a few millimeters to …
CLINICAL CHARACTERISTICS: Familial cerebral cavernous malformations (FCCM) is a disorder characterized by multiple vascular le …
1,570 results