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Year Number of Results
1964 1
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1984 1
1985 1
1987 1
1990 1
1991 2
1993 2
1994 3
1995 4
1996 2
1997 3
1998 3
1999 1
2000 4
2001 1
2002 5
2003 1
2004 1
2005 14
2006 7
2007 6
2008 5
2009 6
2010 5
2012 4
2013 7
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28 results

Results by year

Filters applied: Meta-Analysis, Review, Systematic Review, in the last 5 years, Humans, English. Clear all
Page 1
Cobalt-Induced Cardiomyopathy: Mitochondrial Dysfunction, Oxidative Stress, and Reversible Cardiac Toxicity: A Systematic Review.
Hullon D, Ahad A, Dabiry SM, Mahindra L. Hullon D, et al. Cardiovasc Toxicol. 2026 Feb 2;26(2):24. doi: 10.1007/s12012-026-10099-7. Cardiovasc Toxicol. 2026. PMID: 41622383 Free PMC article. Review.
Diagnostic confirmation required serum cobalt levels typically exceeding 30-100 g/L, with cardiac MRI demonstrating non-ischemic fibrosis and oedema. Chelation therapy reduced cobalt burden but was rarely effective alone. Revision of the MoM implant consistently led …
Diagnostic confirmation required serum cobalt levels typically exceeding 30-100 g/L, with cardiac MRI demonstrating non-ischemic fibrosis an …
Nickel-induced cardiotoxicity: immunopathogenesis, thromboinflammation, and a targeted nanotherapeutic strategy.
Joghataie P, Habibi Z, Bahrampour A, Danjeh M, Molaee P, Yousefi Chermehini N, Forouzin S, Zamanifard S, Nikdoust F. Joghataie P, et al. Int Immunopharmacol. 2026 Feb 1;170:116091. doi: 10.1016/j.intimp.2025.116091. Epub 2025 Dec 24. Int Immunopharmacol. 2026. PMID: 41448006 Review.
Current strategies, including conventional chelation, gene therapy, and nanoparticle interventions, partially reduce systemic Ni burden but fail to fully neutralize intracellular Ni or halt chronic vascular inflammation. ...
Current strategies, including conventional chelation, gene therapy, and nanoparticle interventions, partially reduce systemic …
Iron Balance and Cardiovascular Health: The Double-Edged Role of Deficiency and Overload.
Awashra A, AbuBaha M, Mahafdah B, AbuBaha B, Aldwaik S, Khaled A, Omar L, Abdul-Hafez HA, Emara A, Elgendy MS, Shubietah A. Awashra A, et al. Cardiovasc Toxicol. 2026 Jan 5;26(1):9. doi: 10.1007/s12012-025-10086-4. Cardiovasc Toxicol. 2026. PMID: 41489845 Review.
Targeted assessment and treatment, including supplementation for deficiency and chelation or phlebotomy for overload, may improve outcomes. The ultimate aim of this review is to enhance perioperative management and long-term results for this highly vulnerable population by …
Targeted assessment and treatment, including supplementation for deficiency and chelation or phlebotomy for overload, may improve out …
Systematic review of cardiac ventricular dysfunction in Wilson's disease: mechanisms, diagnostic advancements, and management strategies.
Hullon D, Saraireh THA, Obaidi GA, Mirza H, Fediunina VA, Oskouyan Z, Al-Sudani N, Tawallbeh MA. Hullon D, et al. Future Cardiol. 2025 Dec;21(12):1187-1199. doi: 10.1080/14796678.2025.2554026. Epub 2025 Sep 4. Future Cardiol. 2025. PMID: 40904321 Free PMC article.
Cardiac MRI was highlighted as a valuable diagnostic tool. While chelation remains the cornerstone therapy, gene therapy and liver transplantation are considered for advanced cases. ...
Cardiac MRI was highlighted as a valuable diagnostic tool. While chelation remains the cornerstone therapy, gene therapy …
Essential and Non-Essential Metals and Metalloids and Their Role in Atherosclerosis.
Massie PL, Garcia M, Decker A, Liu R, MazloumiBakhshayesh M, Kulkarni D, Justus MP, Gallardo J, Abrums A, Markle K, Pace C, Campen M, Clark RM. Massie PL, et al. Cardiovasc Toxicol. 2025 Jun;25(6):841-866. doi: 10.1007/s12012-025-09998-y. Epub 2025 Apr 18. Cardiovasc Toxicol. 2025. PMID: 40251456 Review.
Contemporary outcomes of therapeutic trials aimed at chelation therapy of circulating metals to impact cardiovascular outcomes are also discussed. ...
Contemporary outcomes of therapeutic trials aimed at chelation therapy of circulating metals to impact cardiovascular outcomes …
Advances in α-Lipoic Acid for Disease Prevention: Mechanisms and Therapeutic Insights.
Wang Y, Jiang S, He Y, Pang P, Shan H. Wang Y, et al. Molecules. 2025 Apr 29;30(9):1972. doi: 10.3390/molecules30091972. Molecules. 2025. PMID: 40363779 Free PMC article. Review.
This review provides a comprehensive overview of the biochemical properties of ALA, including its direct free-radical-scavenging activity, regeneration of endogenous antioxidants, chelation of metal ions, and modulation of inflammatory responses. We also highlight the curr …
This review provides a comprehensive overview of the biochemical properties of ALA, including its direct free-radical-scavenging activity, r …
Long-Term Cognitive Decline After Subarachnoid Hemorrhage: Pathophysiology, Management, and Future Directions.
Aydin S, Peker S. Aydin S, et al. Stroke. 2025 Apr;56(4):1106-1111. doi: 10.1161/STROKEAHA.124.049969. Epub 2025 Mar 4. Stroke. 2025. PMID: 40035134 Review.
These have emerging treatments that offer promise for the mitigation of effects such as inflammation, iron chelation, and microvascular dysfunction. Genetic predispositions have been associated with post-subarachnoid hemorrhage cognitive outcomes and emphasize a role for p …
These have emerging treatments that offer promise for the mitigation of effects such as inflammation, iron chelation, and microvascul …
Mechanisms Underlying Iron Deficiency-Induced Cardiac Disorders: Implications for Treatment.
Cirovic A, Starcevic A, Ivanovski A, Bogicevic D, Orisakwe OE, Cirovic A. Cirovic A, et al. Discov Med. 2025 Jan;37(192):31-41. doi: 10.24976/Discov.Med.202537192.3. Discov Med. 2025. PMID: 39851221 Free article. Review.
Therefore, we propose that co-treatment with iron and aldosterone antagonists could enhance cardiac iron uptake and improve the overall effectiveness of the therapy. Additionally, vitamin D supplementation prior to the onset of disease and chelation therapy a …
Therefore, we propose that co-treatment with iron and aldosterone antagonists could enhance cardiac iron uptake and improve the overall effe …
Thalassemia and iron overload cardiomyopathy: Pathophysiological insights, clinical implications, and management strategies.
Ansharullah BA, Sutanto H, Romadhon PZ. Ansharullah BA, et al. Curr Probl Cardiol. 2025 Jan;50(1):102911. doi: 10.1016/j.cpcardiol.2024.102911. Epub 2024 Oct 28. Curr Probl Cardiol. 2025. PMID: 39477176 Review.
Management approaches focusing on iron chelation therapy, lifestyle modifications, and advanced interventions like gene therapy are explored. The review also highlights the importance of early diagnosis, regular monitoring, and patient adherence to therapy …
Management approaches focusing on iron chelation therapy, lifestyle modifications, and advanced interventions like gene the …
28 results