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2022 4
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Promising clopidogrel analogs may overcome clopidogrel resistance: 2025 update.
Xie HG, Jiang LP, Tai T, Jia YM, Ji JZ, Mi QY. Xie HG, et al. Biochem Pharmacol. 2025 Dec;242(Pt 4):117330. doi: 10.1016/j.bcp.2025.117330. Epub 2025 Sep 13. Biochem Pharmacol. 2025. PMID: 40953648 Review.
DT-678 and evategrel are considered the best clopidogrel analogs that may overcome clopidogrel resistance due to their superior efficacy and safety profiles over clopidogrel....
DT-678 and evategrel are considered the best clopidogrel analogs that may overcome clopidogrel resistance due to their superio …
Cytochrome P-450 CYP2C19 genetic polymorphism and its relation with clopidogrel resistance.
Nawaz U, Noor M, Waheed A. Nawaz U, et al. J Pak Med Assoc. 2023 Dec;73(12):2388-2392. doi: 10.47391/JPMA.8025. J Pak Med Assoc. 2023. PMID: 38083918
OBJECTIVES: To find out the prevalence of CYP2C19*2 genetic polymorphism in ischaemic heart disease patients, and to determine its relation with clopidogrel resistance in different genotype groups. METHODS: The cross-sectional study was conducted from August 2015 to …
OBJECTIVES: To find out the prevalence of CYP2C19*2 genetic polymorphism in ischaemic heart disease patients, and to determine its relation …
Factors associated with clopidogrel resistance and clinical outcomes in ischemic cerebrovascular disease: A retrospective study.
Wu Y, Shen H, Cai B, Chen C, Yin Q, Zhao Y, Zhou G. Wu Y, et al. J Stroke Cerebrovasc Dis. 2024 Jun;33(6):107684. doi: 10.1016/j.jstrokecerebrovasdis.2024.107684. Epub 2024 Mar 20. J Stroke Cerebrovasc Dis. 2024. PMID: 38518890
OBJECTIVE: Clopidogrel resistance may lead to the recurrence of cerebrovascular diseases. We aimed to identify potential factors associated with clopidogrel resistance and evaluate the clinical outcomes of the patients. ...CONCLUSIONS: The risk of c …
OBJECTIVE: Clopidogrel resistance may lead to the recurrence of cerebrovascular diseases. We aimed to identify potential facto …
Multi-institutional patterns of clopidogrel response among patients undergoing transcarotid artery revascularization.
Rokosh RS, Rockman C, Garg K, Wang SK, Motaganahalli RL, Schroeder AC, Sobraske PJ, Stoner MC, Tarbunou YA, Marmor RA, Malas MB, Maldonado TS. Rokosh RS, et al. Vascular. 2024 Jun;32(3):558-564. doi: 10.1177/17085381221142219. Epub 2022 Nov 25. Vascular. 2024. PMID: 36428145
The most common DAPT regimen is aspirin and clopidogrel, a P2Y12 receptor antagonist; however, the prevalence of clopidogrel resistance (CR) in patients undergoing percutaneous coronary interventions may exceed 60%. ...
The most common DAPT regimen is aspirin and clopidogrel, a P2Y12 receptor antagonist; however, the prevalence of clopidogrel resis …
The Complement System and C4b-Binding Protein: A Focus on the Promise of C4BPalpha as a Biomarker to Predict Clopidogrel Resistance.
Xie HG, Jiang LP, Tai T, Ji JZ, Mi QY. Xie HG, et al. Mol Diagn Ther. 2024 Mar;28(2):189-199. doi: 10.1007/s40291-023-00691-w. Epub 2024 Jan 23. Mol Diagn Ther. 2024. PMID: 38261250 Review.
Plasma C4BPalpha levels appear to be significantly higher in patients sensitive to, rather than resistant to, clopidogrel, and we suggest that a plasma C4BPalpha measurement could be used to predict clopidogrel resistance in the clinical settings....
Plasma C4BPalpha levels appear to be significantly higher in patients sensitive to, rather than resistant to, clopidogrel, and we suggest th …
Lower Plasma miR-223 Level Is Associated with Clopidogrel Resistance in Acute Coronary Syndrome: A Systematic Review and Meta-Analysis.
Cheng H, Yang M, Hao J, Chen K, Tan Q, He S, Mao F, Yang M, Lin Y, Yang J. Cheng H, et al. J Interv Cardiol. 2023 Aug 17;2023:9322188. doi: 10.1155/2023/9322188. eCollection 2023. J Interv Cardiol. 2023. PMID: 37637249 Free PMC article.
OBJECTIVES: To evaluate the relationship between the plasma miR-223 expression level and clopidogrel resistance in acute coronary syndrome (ACS) patients. METHODS: We performed a search for publications using online databases including PubMed, EMBASE, Cochrane Libra …
OBJECTIVES: To evaluate the relationship between the plasma miR-223 expression level and clopidogrel resistance in acute coron …
Association of clopidogrel resistance and ABCD-GENE score with long-term clinical prognosis in patients with ischemic stroke or TIA.
Kang Y, Guo L, Li Q, Liu C, Jin W, Huang M, Liu Y, Tang C, Zhu J, Zhang L. Kang Y, et al. Rev Neurol (Paris). 2024 Sep;180(7):682-688. doi: 10.1016/j.neurol.2024.03.011. Epub 2024 May 7. Rev Neurol (Paris). 2024. PMID: 38719768
BACKGROUND: Clopidogrel resistance (CR) is associated with adverse clinical outcomes in acute ischemic stroke or transient ischemic attack (TIA) patients. ...
BACKGROUND: Clopidogrel resistance (CR) is associated with adverse clinical outcomes in acute ischemic stroke or transient isc …
Construction of a Machine Learning-Based Clopidogrel Resistance Risk Prediction Model.
Wang RY, Yan SD, Zeng JQ, Mu T, Yan Y, Zhao YY, Xie L, Liu LL. Wang RY, et al. Cardiovasc Toxicol. 2025 Oct;25(10):1548-1560. doi: 10.1007/s12012-025-10026-2. Epub 2025 Jul 14. Cardiovasc Toxicol. 2025. PMID: 40658305
Modeling was performed using Logistic Regression, LGBM Classifier, Random Forest Classifier, and SVC machine learning models, followed by model comparison, to ultimately construct the clopidogrel resistance risk prediction model. The clopidogrel resistance …
Modeling was performed using Logistic Regression, LGBM Classifier, Random Forest Classifier, and SVC machine learning models, followed by mo …
42 results