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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1968 1
1971 2
1973 2
1974 1
1975 16
1976 19
1977 20
1978 15
1979 27
1980 25
1981 28
1982 43
1983 51
1984 79
1985 73
1986 69
1987 54
1988 69
1989 102
1990 94
1991 112
1992 116
1993 173
1994 144
1995 160
1996 198
1997 194
1998 194
1999 209
2000 249
2001 195
2002 258
2003 291
2004 364
2005 349
2006 425
2007 512
2008 576
2009 537
2010 633
2011 696
2012 801
2013 800
2014 895
2015 944
2016 990
2017 1078
2018 1088
2019 1120
2020 1209
2021 1258
2022 1149
2023 1111
2024 395

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5,120 results

Results by year

Filters applied: Abstract, in the last 5 years. Clear all
Page 1
Stress, depression, and hippocampus: from biochemistry to electrophysiology.
Idunkova A, Lacinova L, Dubiel-Hoppanova L. Idunkova A, et al. Gen Physiol Biophys. 2023 Mar;42(2):107-122. doi: 10.4149/gpb_2023001. Gen Physiol Biophys. 2023. PMID: 36896941 Review.
Major depressive disorder is a very common serious mental illness with increasing prevalence in the population. ...An important role in the pathology of depression is the hippocampus as a center for cognition and memory. ...
Major depressive disorder is a very common serious mental illness with increasing prevalence in the population. ...An importan …
Neuroplasticity in cognitive and psychological mechanisms of depression: an integrative model.
Price RB, Duman R. Price RB, et al. Mol Psychiatry. 2020 Mar;25(3):530-543. doi: 10.1038/s41380-019-0615-x. Epub 2019 Dec 4. Mol Psychiatry. 2020. PMID: 31801966 Free PMC article. Review.
Chronic stress and depressive-like behaviors in basic neuroscience research have been associated with impairments of neuroplasticity, such as neuronal atrophy and synaptic loss in the medial prefrontal cortex (mPFC) and hippocampus. The current review presents a nov …
Chronic stress and depressive-like behaviors in basic neuroscience research have been associated with impairments of neuroplasticity, …
Neuroinflammation and depression: A review.
Troubat R, Barone P, Leman S, Desmidt T, Cressant A, Atanasova B, Brizard B, El Hage W, Surget A, Belzung C, Camus V. Troubat R, et al. Eur J Neurosci. 2021 Jan;53(1):151-171. doi: 10.1111/ejn.14720. Epub 2020 Mar 20. Eur J Neurosci. 2021. PMID: 32150310 Review.
Some recent clinical and preclinical evidence suggests that neuroinflammation is a key factor that interacts with the three neurobiological correlates of major depressive disorder: depletion of brain serotonin, dysregulation of the hypothalamus-pituitary-adrenal (HP …
Some recent clinical and preclinical evidence suggests that neuroinflammation is a key factor that interacts with the three neurobiological …
Physical activity and depression: Towards understanding the antidepressant mechanisms of physical activity.
Kandola A, Ashdown-Franks G, Hendrikse J, Sabiston CM, Stubbs B. Kandola A, et al. Neurosci Biobehav Rev. 2019 Dec;107:525-539. doi: 10.1016/j.neubiorev.2019.09.040. Epub 2019 Oct 2. Neurosci Biobehav Rev. 2019. PMID: 31586447 Review.
Physical activity can treat and prevent depressive symptoms, but its antidepressant mechanisms are yet to be established. ...We conclude by presenting a conceptual framework of the key biological and psychosocial mechanisms underlying the relationship between physical acti …
Physical activity can treat and prevent depressive symptoms, but its antidepressant mechanisms are yet to be established. ...We concl …
Dysregulation of adult hippocampal neuroplasticity in major depression: pathogenesis and therapeutic implications.
Tartt AN, Mariani MB, Hen R, Mann JJ, Boldrini M. Tartt AN, et al. Mol Psychiatry. 2022 Jun;27(6):2689-2699. doi: 10.1038/s41380-022-01520-y. Epub 2022 Mar 30. Mol Psychiatry. 2022. PMID: 35354926 Free PMC article. Review.
Major depressive disorder (MDD) was previously hypothesized to be a disease of monoamine deficiency in which low levels of monoamines in the synaptic cleft were believed to underlie depressive symptoms. More recently, however, there has been a paradigm shift …
Major depressive disorder (MDD) was previously hypothesized to be a disease of monoamine deficiency in which low levels of mon …
Cognitive impairment and depression: Meta-analysis of structural magnetic resonance imaging studies.
Zacková L, Jáni M, Brázdil M, Nikolova YS, Marečková K. Zacková L, et al. Neuroimage Clin. 2021;32:102830. doi: 10.1016/j.nicl.2021.102830. Epub 2021 Sep 16. Neuroimage Clin. 2021. PMID: 34560530 Free PMC article. Review.
Longitudinal comorbidity of depression and cognitive impairment has been reported by number of epidemiological studies but the underlying mechanisms explaining the link between affective problems and cognitive decline are not very well understood. Imaging studies have typi …
Longitudinal comorbidity of depression and cognitive impairment has been reported by number of epidemiological studies but the underl …
Orbitofrontal cortex-hippocampus potentiation mediates relief for depression: A randomized double-blind trial and TMS-EEG study.
Han S, Li XX, Wei S, Zhao D, Ding J, Xu Y, Yu C, Chen Z, Zhou DS, Yuan TF. Han S, et al. Cell Rep Med. 2023 Jun 20;4(6):101060. doi: 10.1016/j.xcrm.2023.101060. Epub 2023 May 31. Cell Rep Med. 2023. PMID: 37263267 Free PMC article. Clinical Trial.
This study analyzes TMS-electroencephalogram (EEG) data from 64 healthy control (HC) subjects and 53 patients with major depressive disorder (MDD) before and after rTMS treatment. Prior to treatment, patients with MDD have lower activity in the DLPFC, the hippoca
This study analyzes TMS-electroencephalogram (EEG) data from 64 healthy control (HC) subjects and 53 patients with major depressive
The Eph receptor A4 plays a role in demyelination and depression-related behavior.
Li Y, Su P, Chen Y, Nie J, Yuan TF, Wong AH, Liu F. Li Y, et al. J Clin Invest. 2022 Apr 15;132(8):e152187. doi: 10.1172/JCI152187. J Clin Invest. 2022. PMID: 35271507 Free PMC article.
Abnormal myelination is seen in brain disorders such as major depressive disorder (MDD), but the molecular mechanisms connecting demyelination with the pathobiology remain largely unknown. ...Our results provide insights into the etiology of depressive sympto …
Abnormal myelination is seen in brain disorders such as major depressive disorder (MDD), but the molecular mechanisms connecti …
Activating newborn neurons suppresses depression and anxiety-like behaviors.
Tunc-Ozcan E, Peng CY, Zhu Y, Dunlop SR, Contractor A, Kessler JA. Tunc-Ozcan E, et al. Nat Commun. 2019 Aug 21;10(1):3768. doi: 10.1038/s41467-019-11641-8. Nat Commun. 2019. PMID: 31434877 Free PMC article.
The etiology of major depressive disorder (MDD), the leading cause of worldwide disability, is unknown. ...Remarkably, activating these neurons is sufficient to alleviate depression-like behavior and reverse the adverse effects of unpredictable chronic mild s …
The etiology of major depressive disorder (MDD), the leading cause of worldwide disability, is unknown. ...Remarkably, activat …
Behavioral, inflammatory and neurochemical disturbances in LPS and UCMS-induced mouse models of depression.
Zhao X, Cao F, Liu Q, Li X, Xu G, Liu G, Zhang Y, Yang X, Yi S, Xu F, Fan K, Ma J. Zhao X, et al. Behav Brain Res. 2019 May 17;364:494-502. doi: 10.1016/j.bbr.2017.05.064. Epub 2017 May 29. Behav Brain Res. 2019. PMID: 28572058
Further, LPS-stressed mice showed robuster expression and release of TNF-alpha, IL-1beta and IL-6 in serum and depression-related brain areas (prefrontal cortex, hippocampus and striatum) as compared to UCMS-stressed mice. ...Our study strongly imply that hippoca
Further, LPS-stressed mice showed robuster expression and release of TNF-alpha, IL-1beta and IL-6 in serum and depression-related bra …
5,120 results