Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 2
1991 2
1992 1
1999 1
2000 1
2008 1
2009 1
2010 2
2011 1
2012 9
2013 2
2014 4
2015 4
2016 2
2018 3
2019 5
2020 3
2021 7
2022 4
2023 1
2024 2
2025 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

51 results

Results by year

Filters applied: . Clear all
Page 1
2,7-Phloroglucinol-6,6'-bieckol from Ecklonia cava ameliorates nanoplastics-induced premature endothelial senescence and dysfunction.
Sim HH, Shiwakoti S, Lee JH, Lee IY, Ok Y, Lim HK, Ko JY, Oak MH. Sim HH, et al. Sci Total Environ. 2024 Nov 1;949:175007. doi: 10.1016/j.scitotenv.2024.175007. Epub 2024 Jul 23. Sci Total Environ. 2024. PMID: 39053557
This study investigates the efficacy of Ecklonia cava extract (ECE) in preventing NPs-induced premature vascular senescence and dysfunction. ...Moreover, PHB also improved NPs-induced vascular dysfunction by upregulating endothelial nitric oxide synthase (eNO …
This study investigates the efficacy of Ecklonia cava extract (ECE) in preventing NPs-induced premature vascular senescence an …
Anti-obesity effects of a standardized ethanol extract of Eisenia bicyclis by regulating the AMPK signaling pathway in 3T3-L1 cells and HFD-induced mice.
Yoon YS, Chung KS, Lee SY, Heo SW, Kim YR, Lee JK, Kim H, Park S, Shin YK, Lee KT. Yoon YS, et al. Food Funct. 2024 Jun 17;15(12):6424-6437. doi: 10.1039/d4fo00759j. Food Funct. 2024. PMID: 38771619
Obesity requires treatment to mitigate the potential development of further metabolic disorders, including diabetes, hyperlipidemia, tumor growth, and non-alcoholic fatty liver disease. We investigated the anti-obesity effect of a 30% ethanol extract of Eisenia b
Obesity requires treatment to mitigate the potential development of further metabolic disorders, including diabetes, hyperlipidemia, …
Anti-Hypercholesterolemia Effects of Edible Seaweed Extracts and Metabolomic Changes in Hep-G2 and Caco-2 Cell Lines.
Coelho M, Pacheco R. Coelho M, et al. Life (Basel). 2023 Jun 5;13(6):1325. doi: 10.3390/life13061325. Life (Basel). 2023. PMID: 37374108 Free PMC article.
The drugs currently available for hypercholesterolemia control have several side effects, so it is necessary to develop new effective and safer therapies. Seaweeds serve as sources of several bioactive compounds with claimed beneficial effects. Eisenia bicyclis
The drugs currently available for hypercholesterolemia control have several side effects, so it is necessary to develop new effective …
Nanoformulation of Seaweed Eisenia bicyclis in Albumin Nanoparticles Targeting Cardiovascular Diseases: In Vitro and In Vivo Evaluation.
Pinto S, Gaspar MM, Ascensão L, Faísca P, Reis CP, Pacheco R. Pinto S, et al. Mar Drugs. 2022 Sep 27;20(10):608. doi: 10.3390/md20100608. Mar Drugs. 2022. PMID: 36286431 Free PMC article.
This study aimed to design a novel oral formulation of bovine albumin serum nanoparticles (BSA NPs) loaded with an extract of Eisenia bicyclis and to validate its beneficial health effects, particularly targeting hypercholesterolemia and CVD prevention. Small …
This study aimed to design a novel oral formulation of bovine albumin serum nanoparticles (BSA NPs) loaded with an extract of Eisenia
Edible algae (Ecklonia cava) bioprocessed with mycelia of shiitake (Lentinula edodes) mushrooms in liquid culture and its isolated fractions protect mice against allergic asthma.
Lee KH, Jang YJ, Hwang WS, Kwon KS, Lee WY, Kim J, Kim SP, Friedman M. Lee KH, et al. BMC Complement Med Ther. 2022 Sep 17;22(1):242. doi: 10.1186/s12906-022-03705-y. BMC Complement Med Ther. 2022. PMID: 36115955 Free PMC article.
BACKGROUND: Ecklonia cava is an edible marine brown alga harvested from the ocean that is widely consumed in Asian countries as a health-promoting medicinal food The objective of the present study is to evaluate the anti-asthma mechanism of a new functional food produced b …
BACKGROUND: Ecklonia cava is an edible marine brown alga harvested from the ocean that is widely consumed in Asian countries as a hea …
Ecklonia cava extracts decrease hypertension-related vascular calcification by modulating PGC-1alpha and SOD2.
Byun KA, Oh S, Yang JY, Lee SY, Son KH, Byun K. Byun KA, et al. Biomed Pharmacother. 2022 Sep;153:113283. doi: 10.1016/j.biopha.2022.113283. Epub 2022 Jun 16. Biomed Pharmacother. 2022. PMID: 35717781 Free article.
Vascular calcification (VC) is induced by a decrease in sirtuin 3 (SIRT3) and superoxide dismutase (SOD)2 and increases mitochondrial reactive oxygen species (mtROS), eventually leading to mitochondrial dysfunction and phenotype alterations in vascular smooth muscle
Vascular calcification (VC) is induced by a decrease in sirtuin 3 (SIRT3) and superoxide dismutase (SOD)2 and increases mitochondrial
Pharmacological actions of dieckol on modulation of platelet functions and thrombus formation via integrin alpha(IIb)beta(3) and cAMP signaling.
Irfan M, Kwon TH, Kwon HW, Rhee MH. Irfan M, et al. Pharmacol Res. 2022 Mar;177:106088. doi: 10.1016/j.phrs.2022.106088. Epub 2022 Jan 14. Pharmacol Res. 2022. PMID: 35038555
BACKGROUND AND PURPOSE: Dieckol is a phlorotannin that can be found in seaweeds, particularly in Eisenia bicyclis (brown algae) and is known to have anti-oxidant, anti-inflammatory, and anti-microbial properties. It also possesses anti-thrombotic and p …
BACKGROUND AND PURPOSE: Dieckol is a phlorotannin that can be found in seaweeds, particularly in Eisenia bicyclis (brow …
Dieckol Reduces Muscle Atrophy by Modulating Angiotensin Type II Type 1 Receptor and NADPH Oxidase in Spontaneously Hypertensive Rats.
Oh S, Yang JY, Park CH, Son KH, Byun K. Oh S, et al. Antioxidants (Basel). 2021 Sep 30;10(10):1561. doi: 10.3390/antiox10101561. Antioxidants (Basel). 2021. PMID: 34679696 Free PMC article.
The renin-angiotensin system is involved in the development of hypertension and sarcopenia. Increased levels of angiotensin II (Ang II) lead to upregulation of Ang II type 1 receptor (AT1R), which results in increasing reactive oxygen species (ROS) by NAD(P)H oxidase (Nox) …
The renin-angiotensin system is involved in the development of hypertension and sarcopenia. Increased levels of angiotensin II (Ang I …
In Vitro and In Silico Characterization of G-Protein Coupled Receptor (GPCR) Targets of Phlorofucofuroeckol-A and Dieckol.
Paudel P, Seong SH, Park SE, Ryu JH, Jung HA, Choi JS. Paudel P, et al. Mar Drugs. 2021 Jun 4;19(6):326. doi: 10.3390/md19060326. Mar Drugs. 2021. PMID: 34199834 Free PMC article.
Phlorotannins are polyphenolic compounds in marine alga, especially the brown algae. Among numerous phlorotannins, dieckol and phlorofucofuroeckol-A (PFF-A) are the major ones and despite a wider biological activity profile, knowledge of the G protein-coupled recept …
Phlorotannins are polyphenolic compounds in marine alga, especially the brown algae. Among numerous phlorotannins, dieckol and phl
Ecklonia cava Extract and Its Derivative Dieckol Promote Vasodilation by Modulating Calcium Signaling and PI3K/AKT/eNOS Pathway in In Vitro and In Vivo Models.
Lu YA, Je JG, Hwang J, Jeon YJ, Ryu B. Lu YA, et al. Biomedicines. 2021 Apr 19;9(4):438. doi: 10.3390/biomedicines9040438. Biomedicines. 2021. PMID: 33921856 Free PMC article.
In the present study, we extracted and isolated dieckol from Ecklonia cava and investigated calcium transit-enhanced vasodilation. Calcium modulation via the well-known M3 muscarinic acetylcholine receptor (AchM3R), which is linked to NO formation, was invest …
In the present study, we extracted and isolated dieckol from Ecklonia cava and investigated calcium transit-enhanced vasodi
51 results