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Page 1
The molecular genetics of adrenal cushing.
Vaduva P, Bertherat J. Vaduva P, et al. Hormones (Athens). 2024 Dec;23(4):601-610. doi: 10.1007/s42000-024-00608-0. Epub 2024 Oct 10. Hormones (Athens). 2024. PMID: 39388056 Review.
Unilateral cortisol-producing adenoma (CPA), a benign tumor, and adrenocortical carcinoma (ACC), a malignant tumor, are more frequent than bilateral adrenal nodular diseases (primary bilateral macronodular adrenal hyperplasia (PBMAH) and primary pigmented nod …
Unilateral cortisol-producing adenoma (CPA), a benign tumor, and adrenocortical carcinoma (ACC), a malignant tumor, are more frequent than b …
Clinical, Pathophysiologic, Genetic, and Therapeutic Progress in Primary Bilateral Macronodular Adrenal Hyperplasia.
Bertherat J, Bourdeau I, Bouys L, Chasseloup F, Kamenický P, Lacroix A. Bertherat J, et al. Endocr Rev. 2023 Jul 11;44(4):567-628. doi: 10.1210/endrev/bnac034. Endocr Rev. 2023. PMID: 36548967
Patients with primary bilateral macronodular adrenal hyperplasia (PBMAH) usually present bilateral benign adrenocortical macronodules at imaging and variable levels of cortisol excess. ...
Patients with primary bilateral macronodular adrenal hyperplasia (PBMAH) usually present bilateral benign adrenocortica …
ARMC5-negative primary bilateral macronodular adrenal hyperplasia.
Sol B, Carprieaux M, De Leu N. Sol B, et al. BMJ Case Rep. 2023 Jul 6;16(7):e254099. doi: 10.1136/bcr-2022-254099. BMJ Case Rep. 2023. PMID: 37419498 Free PMC article.
Abdominal imaging showed bilateral macronodular adrenals, measuring 58.9 29.7 mm on the right and 55.6 42.6 mm on the left. Primary bilateral macronodular adrenal hyperplasia was confirmed by pathology after bilateral adrenalectomy. ...Genetic sequencing …
Abdominal imaging showed bilateral macronodular adrenals, measuring 58.9 29.7 mm on the right and 55.6 42.6 mm on the left. Primary bila …
Primary bilateral macronodular adrenal hyperplasia: definitely a genetic disease.
Cavalcante IP, Berthon A, Fragoso MC, Reincke M, Stratakis CA, Ragazzon B, Bertherat J. Cavalcante IP, et al. Nat Rev Endocrinol. 2022 Nov;18(11):699-711. doi: 10.1038/s41574-022-00718-y. Epub 2022 Aug 3. Nat Rev Endocrinol. 2022. PMID: 35922573 Review.
Primary bilateral macronodular adrenal hyperplasia (PBMAH) is an adrenal cause of Cushing syndrome. Nowadays, a PBMAH diagnosis is more frequent than previously, as a result of progress in the diagnostic methods for adrenal incidentalomas, which are widely av …
Primary bilateral macronodular adrenal hyperplasia (PBMAH) is an adrenal cause of Cushing syndrome. Nowadays, a PBMAH d …
Current approach of primary bilateral adrenal hyperplasia.
Delivanis DA, Vassiliadi DA, Tsagarakis S. Delivanis DA, et al. Curr Opin Endocrinol Diabetes Obes. 2022 Jun 1;29(3):243-252. doi: 10.1097/MED.0000000000000725. Curr Opin Endocrinol Diabetes Obes. 2022. PMID: 35621176 Review.
Based on the size of the nodules, PBAH is subdivided into primary bilateral macronodular adrenal hyperplasia (PBMAH) and micronodular adrenal hyperplasia. A substantial proportion of patients with PBMAH harbor a germline mutation of the armadillo repeat conta …
Based on the size of the nodules, PBAH is subdivided into primary bilateral macronodular adrenal hyperplasia (PBMAH) an …
Clinical Review: The Approach to the Evaluation and Management of Bilateral Adrenal Masses.
Sweeney AT, Hamidi O, Dogra P, Athimulam S, Correa R, Blake MA, McKenzie T, Vaidya A, Pacak K, Hamrahian AH, Bancos I. Sweeney AT, et al. Endocr Pract. 2024 Oct;30(10):987-1002. doi: 10.1016/j.eprac.2024.06.015. Epub 2024 Aug 3. Endocr Pract. 2024. PMID: 39103149 Review.
Specific clinical scenarios presented here include cases of bilateral adrenal adenomas, hemorrhage, pheochromocytomas, metastatic disease, myelolipomas, as well as primary bilateral macronodular adrenal hyperplasia. RESULTS: Bilateral adrenal masses represent …
Specific clinical scenarios presented here include cases of bilateral adrenal adenomas, hemorrhage, pheochromocytomas, metastatic disease, m …
Long-term cardiometabolic outcomes of primary bilateral macronodular adrenal hyperplasia.
Zhou H, Zhang P, Yin Y, Liu L, Li J, Xu H, Fan Y, Su X, Lyu Z, Gu W, Mu Y. Zhou H, et al. J Endocrinol Invest. 2025 Jun;48(6):1403-1414. doi: 10.1007/s40618-025-02561-0. Epub 2025 Apr 19. J Endocrinol Invest. 2025. PMID: 40252189
PURPOSE: This study investigated long-term alterations in cardiometabolic comorbidities among patients with primary bilateral macronodular adrenal hyperplasia (PBMAH) who received surgical or conservative treatments. ...
PURPOSE: This study investigated long-term alterations in cardiometabolic comorbidities among patients with primary bilateral macronodula …
PDE11A Is a Phenotype Modulator of Primary Bilateral Macronodular Adrenal Hyperplasia: Results of a 334-Patient Series.
Vaduva P, Bouys L, Jouinot A, Espiard S, Chansavang A, Berthon A, Néou M, Vaczlavik A, Violon F, Charchar H, Kroiss M, Raverot G, Lasolle H, Guignat L, Libé R, Assié G, Tabarin A, Kamenicky P, Pasmant E, Fragoso M, Stratakis C, Ragazzon B, Bertherat J. Vaduva P, et al. J Clin Endocrinol Metab. 2025 Aug 7;110(9):e2946-e2955. doi: 10.1210/clinem/dgae918. J Clin Endocrinol Metab. 2025. PMID: 39774659 Free PMC article.
CONTEXT: Primary bilateral macronodular adrenal hyperplasia (PBMAH), the most common cause of Cushing syndrome due to bilateral nodules, is a heterogeneous disease at the clinical, hormonal, and morphological levels. ...
CONTEXT: Primary bilateral macronodular adrenal hyperplasia (PBMAH), the most common cause of Cushing syndrome due to b …
The mutational landscape of ARMC5 in Primary Bilateral Macronodular Adrenal Hyperplasia: an update.
Bouys L, Vaczlavik A, Cavalcante IP, Violon F, Jouinot A, Berthon A, Vaduva P, Espiard S, Perlemoine K, Kamenicky P, Vantyghem MC, Tabarin A, Raverot G, Ronchi CL, Dischinger U, Reincke M, Fragoso MC, Stratakis CA, Chansavang A, Pasmant E, Ragazzon B, Bertherat J; COMETE and ENSAT Networks. Bouys L, et al. Orphanet J Rare Dis. 2025 Feb 5;20(1):51. doi: 10.1186/s13023-025-03554-1. Orphanet J Rare Dis. 2025. PMID: 39910635 Free PMC article. Review.
BACKGROUND: Primary Bilateral Macronodular Adrenal Hyperplasia (PBMAH) is a rare cause of Cushing's syndrome due to bilateral adrenocortical macronodules. ...
BACKGROUND: Primary Bilateral Macronodular Adrenal Hyperplasia (PBMAH) is a rare cause of Cushing's syndrome due to bil …
Germline targeted next-generation sequencing in patients with adrenal incidentalomas.
Messina E, Inglesi A, Puglisi S, Barač Nekić A, Morelli V, Alessi Y, Zibar Tomsic K, Palmieri S, Tomaiuolo P, Grosso E, Ferraù F, Chiodini I, Kastelan D, Pia A, Scatolini M, Reimondo G, Terzolo M. Messina E, et al. Front Endocrinol (Lausanne). 2025 Oct 2;16:1685220. doi: 10.3389/fendo.2025.1685220. eCollection 2025. Front Endocrinol (Lausanne). 2025. PMID: 41113712 Free PMC article.
54 results