Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 1
2009 1
2011 1
2012 2
2013 2
2014 1
2015 7
2016 2
2017 3
2018 4
2019 3
2020 6
2021 3
2022 2
2023 5
2024 6
2025 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

40 results

Results by year

Filters applied: . Clear all
Page 1
Genetic aspects of monomorphic teratozoospermia: a review.
De Braekeleer M, Nguyen MH, Morel F, Perrin A. De Braekeleer M, et al. J Assist Reprod Genet. 2015 Apr;32(4):615-23. doi: 10.1007/s10815-015-0433-2. Epub 2015 Feb 25. J Assist Reprod Genet. 2015. PMID: 25711835 Free PMC article. Review.
Teratozoospermia is characterized by the presence of spermatozoa with abnormal morphology over 85 % in sperm. When all the spermatozoa display a unique abnormality, teratozoospermia is said to be monomorphic. ...Macrozoospermia is defined as the presen …
Teratozoospermia is characterized by the presence of spermatozoa with abnormal morphology over 85 % in sperm. When all the …
Genetics of teratozoospermia: Back to the head.
Beurois J, Cazin C, Kherraf ZE, Martinez G, Celse T, Touré A, Arnoult C, Ray PF, Coutton C. Beurois J, et al. Best Pract Res Clin Endocrinol Metab. 2020 Dec;34(6):101473. doi: 10.1016/j.beem.2020.101473. Epub 2020 Nov 2. Best Pract Res Clin Endocrinol Metab. 2020. PMID: 33183966 Review.
Patients presenting with a monomorphic head sperm defects such as globozoospermia or marcrozoospermia were analyzed permitting to identify several key genes for spermatogenesis such as AURKC and DPY19L2. The study of patients with other specific sperm head de …
Patients presenting with a monomorphic head sperm defects such as globozoospermia or marcrozoospermia were analyzed permitting to ide …
Genetic etiological spectrum of sperm morphological abnormalities.
Arora M, Mehta P, Sethi S, Anifandis G, Samara M, Singh R. Arora M, et al. J Assist Reprod Genet. 2024 Nov;41(11):2877-2929. doi: 10.1007/s10815-024-03274-8. Epub 2024 Oct 17. J Assist Reprod Genet. 2024. PMID: 39417902 Review.
PURPOSE: Male infertility manifests in the form of a reduction in sperm count, sperm motility, or the loss of fertilizing ability. While the loss of sperm production can have mixed reasons, sperm structural defects, cumulatively known as teratozoosperm …
PURPOSE: Male infertility manifests in the form of a reduction in sperm count, sperm motility, or the loss of fertilizing abil …
Genetic Causes of Qualitative Sperm Defects: A Narrative Review of Clinical Evidence.
Graziani A, Rocca MS, Vinanzi C, Masi G, Grande G, De Toni L, Ferlin A. Graziani A, et al. Genes (Basel). 2024 May 8;15(5):600. doi: 10.3390/genes15050600. Genes (Basel). 2024. PMID: 38790229 Free PMC article. Review.
In this manuscript, we reviewed the genetic causes of qualitative sperm defects. We distinguished between alterations causing reduced sperm motility (asthenozoospermia) and alterations causing changes in the typical morphology of sperm (teratozoospermia). ... …
In this manuscript, we reviewed the genetic causes of qualitative sperm defects. We distinguished between alterations causing reduced …
Teratozoospermia: spotlight on the main genetic actors in the human.
Coutton C, Escoffier J, Martinez G, Arnoult C, Ray PF. Coutton C, et al. Hum Reprod Update. 2015 Jul-Aug;21(4):455-85. doi: 10.1093/humupd/dmv020. Epub 2015 Apr 17. Hum Reprod Update. 2015. PMID: 25888788 Review.
RESULTS: Molecular studies of numerous unrelated patients with globozoospermia and large-headed spermatozoa confirmed that mutations in DPY19L2 and AURKC are mainly responsible for their respective pathological phenotype. In globozoospermia, the deletion of the tota …
RESULTS: Molecular studies of numerous unrelated patients with globozoospermia and large-headed spermatozoa confirmed that mutations …
Successful intracytoplasmic sperm injection in a macrozoospermia case with novel compound heterozygous aurora kinase C (AURKC) mutations.
Jiang L, Kong F, Yao L, Zhang F, Wu L, Zhang H, Yang G, Wang S, Jin X, Wang X, Tong X, Zhang S. Jiang L, et al. Arch Gynecol Obstet. 2024 Oct;310(4):2211-2221. doi: 10.1007/s00404-024-07619-7. Epub 2024 Aug 12. Arch Gynecol Obstet. 2024. PMID: 39133293
PURPOSE: To explore the application possibility of macrocephalic sperm from a patient with 100% macrocephalic sperm and AURKC gene variations. METHODS: We diagnosed a case of macrozoospermia with 100% macrocephalic sperm and 39.5% multi-tailed …
PURPOSE: To explore the application possibility of macrocephalic sperm from a patient with 100% macrocephalic sperm and AUR …
Male infertility and its genetic causes.
Miyamoto T, Minase G, Okabe K, Ueda H, Sengoku K. Miyamoto T, et al. J Obstet Gynaecol Res. 2015 Oct;41(10):1501-5. doi: 10.1111/jog.12765. Epub 2015 Jul 14. J Obstet Gynaecol Res. 2015. PMID: 26178295 Review.
We discuss here the contribution to male factor infertility of a number of genes identified in the azoospermia factor (AZF) region on the Y chromosome, as well as the autosomally located genes: SYKP3, KLHL10, AURKC and SPATA16. CONCLUSIONS: Non-obstructive azoospermia is t …
We discuss here the contribution to male factor infertility of a number of genes identified in the azoospermia factor (AZF) region on the Y …
Computational study of the potential impact of AURKC missense SNPs on AURKC-INCENP interaction and their correlation to macrozoospermia.
Redouane S, Charoute H, Harmak H, Malki A, Barakat A, Rouba H. Redouane S, et al. J Biomol Struct Dyn. 2023 Nov;41(19):9503-9522. doi: 10.1080/07391102.2022.2142846. Epub 2022 Nov 3. J Biomol Struct Dyn. 2023. PMID: 36326488
Genetic variations of AURKC gene are susceptible to impact AURKC-INCENP interaction, which may affect CPC stability and predispose male subjects to macrozoospermia. ...Seventeen missense SNPs of AURKC were identified as deleterious between all reported …
Genetic variations of AURKC gene are susceptible to impact AURKC-INCENP interaction, which may affect CPC stability and predis …
Meiosis interrupted: the genetics of female infertility via meiotic failure.
Biswas L, Tyc K, El Yakoubi W, Morgan K, Xing J, Schindler K. Biswas L, et al. Reproduction. 2021 Feb;161(2):R13-R35. doi: 10.1530/REP-20-0422. Reproduction. 2021. PMID: 33170803 Free PMC article. Review.
Conception, implantation, and term delivery of developmentally healthy infants require chromosomally normal (euploid) eggs and sperm. The crux of euploid egg production is error-free meiosis. Pathologic genetic variants dysregulate meiotic processes that occur during proph …
Conception, implantation, and term delivery of developmentally healthy infants require chromosomally normal (euploid) eggs and sperm. …
Functions of Aurora kinase C in meiosis and cancer.
Quartuccio SM, Schindler K. Quartuccio SM, et al. Front Cell Dev Biol. 2015 Aug 20;3:50. doi: 10.3389/fcell.2015.00050. eCollection 2015. Front Cell Dev Biol. 2015. PMID: 26347867 Free PMC article. Review.
While Aurora kinase A (AURKA) and B (AURKB) are found in cells throughout the body, significant protein levels of Aurora kinase C (AURKC) are limited to cells that undergo meiosis (sperm and oocyte). Despite its discovery nearly 20 years ago, we know little about th …
While Aurora kinase A (AURKA) and B (AURKB) are found in cells throughout the body, significant protein levels of Aurora kinase C (AURKC …
40 results