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2016 6
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90 results

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Page 1
Diagnostic accuracy of deep learning vs. human raters for detecting osteoporotic vertebral compression fractures in routine CT scans.
Riedel EO, Schinz D, Keicher M, Rühling S, El Husseini M, Pellegrini C, Baum T, Dieckmeyer M, Malagutti L, Seeger I, Walburga AS, Wiestler B, Sollmann N, Löffler MT, Wagner A, Kirschke JS. Riedel EO, et al. Among authors: kirschke js. Eur Radiol. 2026 Feb 24. doi: 10.1007/s00330-026-12393-y. Online ahead of print. Eur Radiol. 2026. PMID: 41733641
OBJECTIVES: Vertebral fractures are severe complications of osteoporosis but are frequently missed on computed tomography (CT). ...Findings Deep learning models specifically trained for vertebral fracture detection and grading can reach comparable performance …
OBJECTIVES: Vertebral fractures are severe complications of osteoporosis but are frequently missed on computed tomography (CT) …
Vertebral-level discrimination of incidental vertebral fractures using volumetric BMD, texture features, and finite element-derived fracture load: an exploratory study.
Strack D, Dieckmeyer M, Sollmann N, Baum T, Kirschke JS, Subburaj K. Strack D, et al. Among authors: kirschke js. Skeletal Radiol. 2026 Feb 16. doi: 10.1007/s00256-026-05147-w. Online ahead of print. Skeletal Radiol. 2026. PMID: 41697300
OBJECTIVE: To assess the discriminatory ability of vertebra-specific volumetric bone mineral density (vBMD), finite element analysis-derived fracture load (FEA-derived FL), and texture analysis (TA) features for incidental vertebral fractures, and to compare …
OBJECTIVE: To assess the discriminatory ability of vertebra-specific volumetric bone mineral density (vBMD), finite element analysis- …
Urinary urgency after traumatic brain injury.
Costain G, Kirschke JN, Cortes C, Monson M, McEchron M. Costain G, et al. Among authors: kirschke jn. BMJ Case Rep. 2025 Oct 13;18(10):e266916. doi: 10.1136/bcr-2025-266916. BMJ Case Rep. 2025. PMID: 41087096
This case study describes a young child who sustained a TBI after a fall from a second-storey window, resulting in a depressed skull fracture in the left frontal region and associated subarachnoid haemorrhage. Surgical intervention was required to stabilise the skull fr
This case study describes a young child who sustained a TBI after a fall from a second-storey window, resulting in a depressed skull frac
Automated extraction of vertebral bone mineral density from imaging with various scan parameters: a cadaver study with correlation to quantitative computed tomography.
Ramschütz C, Kloth C, Vogele D, Baum T, Rühling S, Beer M, Jansen JU, Schlager B, Wilke HJ, Kirschke JS, Sollmann N. Ramschütz C, et al. Among authors: kirschke js. Eur Spine J. 2025 Nov;34(11):5034-5044. doi: 10.1007/s00586-025-09146-8. Epub 2025 Jul 21. Eur Spine J. 2025. PMID: 40694110
PURPOSE: To investigate lumbar vertebral volumetric bone mineral density (vBMD) from ex vivo opportunistic multi-detector computed tomography (MDCT) scans using different protocols, and compare it to dedicated quantitative CT (QCT) values from the same specimens. ...
PURPOSE: To investigate lumbar vertebral volumetric bone mineral density (vBMD) from ex vivo opportunistic multi-detector computed to …
Opportunistic computed tomography (CT) assessment of osteoporosis in patients undergoing transcatheter aortic valve replacement (TAVR).
Paukovitsch M, Fechner T, Felbel D, Moerike J, Rottbauer W, Klömpken S, Brunner H, Kloth C, Beer M, Sekuboyina A, Buckert D, Kirschke JS, Sollmann N. Paukovitsch M, et al. Among authors: kirschke js. Arch Osteoporos. 2025 Jul 17;20(1):100. doi: 10.1007/s11657-025-01579-4. Arch Osteoporos. 2025. PMID: 40676440 Free PMC article.
Thus, opportunistic screening may be a cost-effective way to assess osteoporosis in high-risk populations. BACKGROUND: Osteoporosis is an underdiagnosed condition associated with fractures and frailty, but may be detected in routine computed tomography (CT) s …
Thus, opportunistic screening may be a cost-effective way to assess osteoporosis in high-risk populations. BACKGROUND: Osteoporosi
Simulated low-dose multi-detector computed tomography: spatial effects on surrogate parameters of bone strength at the proximal femur.
Sollmann N, Mei K, Löffler MT, Rühling S, Beer M, Zimmer C, Kirschke JS, Noël PB, Baum T, Carballido-Gamio J. Sollmann N, et al. Among authors: kirschke js. Osteoporos Int. 2025 May;36(5):917-928. doi: 10.1007/s00198-025-07467-4. Epub 2025 Apr 5. Osteoporos Int. 2025. PMID: 40186637 Free PMC article.
This study investigated simulated tube current reduction and sparse sampling for low-dose computed tomography (CT) regarding volumetric bone mineral density (vBMD) and cortical bone thickness (Ct.Th) of the proximal femur. ...CONCLUSIONS: Sparse sampling with SIR ma …
This study investigated simulated tube current reduction and sparse sampling for low-dose computed tomography (CT) regarding volumetric b
Longitudinal assessment of changes in muscle composition using proton density fat fraction and T2* in patients with and without incidental vertebral compression fractures.
Stohldreier Y, Leonhardt Y, Ketschau J, Gassert FT, Makowski MR, Kirschke JS, Feuerriegel GC, Braun P, Schwaiger BJ, Karampinos DC, Hesse N, Gersing AS. Stohldreier Y, et al. Among authors: kirschke js. Front Endocrinol (Lausanne). 2025 Mar 3;16:1549068. doi: 10.3389/fendo.2025.1549068. eCollection 2025. Front Endocrinol (Lausanne). 2025. PMID: 40099253 Free PMC article.
OBJECTIVE: Chemical shift encoded-based water-fat separation magnetic resonance imaging (CSE-MRI) is an emerging noninvasive tool for the assessment of bone and muscle composition. This study aims to examine both the predictive value and the longitudinal change of proton d …
OBJECTIVE: Chemical shift encoded-based water-fat separation magnetic resonance imaging (CSE-MRI) is an emerging noninvasive tool for the as …
Opportunistic osteoporosis screening in intraoperative CT can accurately identify patients with low volumetric bone mineral density and osteoporosis during spine surgery.
Rühling S, Petzsche MRH, Löffler MT, Sollmann N, Baum T, Bodden J, Schwarting J, Lange N, Aftahy K, Wostrack M, Zimmer C, Kirschke JS. Rühling S, et al. Among authors: kirschke js. Eur Spine J. 2025 Apr;34(4):1461-1469. doi: 10.1007/s00586-025-08697-0. Epub 2025 Feb 6. Eur Spine J. 2025. PMID: 39912947
PURPOSE: To evaluate the accuracy of opportunistic measurements of volumetric bone mineral density (vBMD) in intraoperative multi-detector CT (MDCT) scans, using preoperative MDCT as the reference. ...This could enable the identification of patients with low bone ma …
PURPOSE: To evaluate the accuracy of opportunistic measurements of volumetric bone mineral density (vBMD) in intraoperative multi-det …
The identification of low-pathogenic bacteria on removed spinal implants and implications for antimicrobial prophylaxis.
Joerger AK, Butenschoen VM, Feihl S, Rühling S, Kirschke JS, Meyer B, Krieg SM. Joerger AK, et al. Among authors: kirschke js. Brain Spine. 2024 Dec 5;5:104152. doi: 10.1016/j.bas.2024.104152. eCollection 2025. Brain Spine. 2024. PMID: 39741787 Free PMC article.
The latter group was subdivided into cases where implants were exchanged due to adjacent segment degeneration (ASD) and those with elective implant removal after fracture healing. Bacterial cultures from removed implants were analyzed for resistance profiles against the pr …
The latter group was subdivided into cases where implants were exchanged due to adjacent segment degeneration (ASD) and those with elective …
Cervicothoracic volumetric bone mineral density assessed by opportunistic QCT may be a reliable marker for osteoporosis in adults.
Ramschütz C, Sollmann N, El Husseini M, Kupfer K, Paprottka KJ, Löffler MT, Petzsche MRH, Schwarting J, Bodden J, Baum T, Kim SH, Wostrack M, Zimmer C, Kirschke JS, Rühling S. Ramschütz C, et al. Among authors: kirschke js. Osteoporos Int. 2025 Mar;36(3):423-433. doi: 10.1007/s00198-024-07373-1. Epub 2024 Dec 31. Osteoporos Int. 2025. PMID: 39738830 Free PMC article.
The bone density assessment proved feasible, allowing us to propose optimal cut-off values for diagnosing osteoporosis and predicting vertebral fractures in the cervical and thoracic spine. OBJECTIVES: To investigate the performance of cervicothoracic volumet …
The bone density assessment proved feasible, allowing us to propose optimal cut-off values for diagnosing osteoporosis and pre …
90 results