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Anti-Inflammatory Effects of Extracellular Vesicles from Ecklonia cava on 12-O-Tetradecanoylphorbol-13-Acetate-Induced Skin Inflammation in Mice.
Kim G, Lee SY, Oh S, Jang JW, Lee J, Kim HS, Son KH, Byun K. Kim G, et al. Int J Mol Sci. 2024 Nov 21;25(23):12522. doi: 10.3390/ijms252312522. Int J Mol Sci. 2024. PMID: 39684233 Free PMC article.
Steroids, which are often used to treat the inflammation associated with various skin diseases, have several negative side effects. As Ecklonia cava extract has anti-inflammatory effects in various diseases, we evaluated the efficacy of Ecklonia cava-derived extrace …
Steroids, which are often used to treat the inflammation associated with various skin diseases, have several negative side effects. As Ec …
Intratympanic Administration of Dieckol Prevents Ototoxic Hearing Loss.
Li H, Oh SH, Shin HC, Suh MW. Li H, et al. Mar Drugs. 2022 Sep 30;20(10):622. doi: 10.3390/md20100622. Mar Drugs. 2022. PMID: 36286446 Free PMC article.
OBJECTIVE: Systemic administration of dieckol reportedly ameliorates acute hearing loss. In this study, dieckol was delivered to the inner ear by the intratympanic route. ...CONCLUSION: Intratympanic local delivery of dieckol may be a safe and e …
OBJECTIVE: Systemic administration of dieckol reportedly ameliorates acute hearing loss. In this study, dieckol was del …
Effect of Phlorofucofuroeckol A and Dieckol Extracted from Ecklonia cava on Noise-induced Hearing Loss in a Mouse Model.
Woo H, Kim MK, Park S, Han SH, Shin HC, Kim BG, Oh SH, Suh MW, Lee JH, Park MK. Woo H, et al. Mar Drugs. 2021 Aug 1;19(8):443. doi: 10.3390/md19080443. Mar Drugs. 2021. PMID: 34436282 Free PMC article.
One of the well-known causes of hearing loss is noise. Approximately 31.1% of Americans between the ages of 20 and 69 years (61.1 million people) have high-frequency hearing loss associated with noise exposure. In addition, recurrent noise exposure can accelerate ag …
One of the well-known causes of hearing loss is noise. Approximately 31.1% of Americans between the ages of 20 and 69 years (61.1 mil …
Dieckol isolated from a brown alga, Eisenia nipponica, suppresses ear swelling from allergic inflammation in mouse.
Sugiura Y, Usui M, Katsuzaki H, Imai K, Tanaka R, Matsushita T, Miyata M. Sugiura Y, et al. J Food Biochem. 2021 Apr;45(4):e13659. doi: 10.1111/jfbc.13659. Epub 2021 Feb 17. J Food Biochem. 2021. PMID: 33595108
This uncovered the phlorotannin dieckol, which exhibited antiallergic effects in an ear swelling test using mice sensitized by arachidonic acid, 12-O-tetradecanoylphorbol-13-acetate, and oxazolone. ...Consequently, dieckol or the alga containing this phlorota …
This uncovered the phlorotannin dieckol, which exhibited antiallergic effects in an ear swelling test using mice sensitized by …
Eckol from Ecklonia cava Suppresses Immunoglobulin E-mediated Mast Cell Activation and Passive Cutaneous Anaphylaxis in Mice.
Han EJ, Kim HS, Sanjeewa KKA, Herath KHINM, Jeon YJ, Jee Y, Lee J, Kim T, Shim SY, Ahn G. Han EJ, et al. Nutrients. 2020 May 9;12(5):1361. doi: 10.3390/nu12051361. Nutrients. 2020. PMID: 32397556 Free PMC article.
In the present study, we investigated the antiallergic effects of eckol isolated from the marine brown algae, Ecklonia cava using immunoglobulin E (IgE)/bovine serum albumin (BSA)-stimulated mouse bone marrow-derived cultured mast cells (BMCMC) and a mouse model of …
In the present study, we investigated the antiallergic effects of eckol isolated from the marine brown algae, Ecklonia cava us …
Traditional oriental medicine for sensorineural hearing loss: Can ethnopharmacology contribute to potential drug discovery?
Castañeda R, Natarajan S, Jeong SY, Hong BN, Kang TH. Castañeda R, et al. J Ethnopharmacol. 2019 Mar 1;231:409-428. doi: 10.1016/j.jep.2018.11.016. Epub 2018 Nov 12. J Ethnopharmacol. 2019. PMID: 30439402 Review.
RESULTS: This review shows that approximately 25 herbal species and 40 active compounds prescribed in TOM for hearing loss and tinnitus have shown in vitro or in vivo beneficial effects for acquired sensorineural hearing loss produced by noise, aging, ototoxic drugs …
RESULTS: This review shows that approximately 25 herbal species and 40 active compounds prescribed in TOM for hearing loss and tinnit …
Orally Administered Phlorotannins from Eisenia arborea Suppress Chemical Mediator Release and Cyclooxygenase-2 Signaling to Alleviate Mouse Ear Swelling.
Sugiura Y, Usui M, Katsuzaki H, Imai K, Kakinuma M, Amano H, Miyata M. Sugiura Y, et al. Mar Drugs. 2018 Aug 2;16(8):267. doi: 10.3390/md16080267. Mar Drugs. 2018. PMID: 30072652 Free PMC article.
In this study, six purified phlorotannins (eckol; 6,6'-bieckol; 6,8'-bieckol; 8,8'-bieckol; phlorofucofuroeckol (PFF)-A and PFF-B) from Eisenia arborea, orally administered to mice, were examined for their suppression effects on …
In this study, six purified phlorotannins (eckol; 6,6'-bieckol; 6,8'-bieckol; 8,8'-bieckol; phlorofucofuroeck …
Effect of Ecklonia Cava Polyphenol Extract in House Ear Institute-Organ of Corti 1 Cells Against Cisplatin Ototoxicity: A Preliminary Study.
Düzenli U, Olgun Y, Aktaş S, Pamukoğlu A, Altun Z. Düzenli U, et al. Turk Arch Otorhinolaryngol. 2016 Dec;54(4):141-145. doi: 10.5152/tao.2016.1974. Epub 2016 Dec 1. Turk Arch Otorhinolaryngol. 2016. PMID: 29392035 Free PMC article.
Side effects such as nephrotoxicity, neurotoxicity, and ototoxicity lead to dose limitations. Ecklonia cava polyphenol extract (ECP) is a molecule obtained from algae that live in seawater in the Far East. ...METHODS: In this study, we investigated the protective effects o …
Side effects such as nephrotoxicity, neurotoxicity, and ototoxicity lead to dose limitations. Ecklonia cava polyphenol extract (ECP) …
Protective effect of a purified polyphenolic extract from Ecklonia cava against noise-induced hearing loss: Prevention of temporary threshold shift.
Chang MY, Han SY, Shin HC, Byun JY, Rah YC, Park MK. Chang MY, et al. Int J Pediatr Otorhinolaryngol. 2016 Aug;87:178-84. doi: 10.1016/j.ijporl.2016.06.028. Epub 2016 Jun 10. Int J Pediatr Otorhinolaryngol. 2016. PMID: 27368468
OBJECTIVE: Noise is one of the most common causes of hearing loss. Approximately 16% of American teenagers (12-19 years) have hearing loss caused by loud noise. The implication of noise-induced hearing loss (NIHL) in teenagers has received increasing attentio …
OBJECTIVE: Noise is one of the most common causes of hearing loss. Approximately 16% of American teenagers (12-19 years) have hear …
Protective effects of the seaweed phlorotannin polyphenolic compound dieckol on gentamicin-induced damage in auditory hair cells.
Chang MY, Byon SH, Shin HC, Han SE, Kim JY, Byun JY, Lee JD, Park MK. Chang MY, et al. Int J Pediatr Otorhinolaryngol. 2016 Apr;83:31-6. doi: 10.1016/j.ijporl.2016.01.014. Epub 2016 Jan 25. Int J Pediatr Otorhinolaryngol. 2016. PMID: 26968049
OBJECTIVES: Drug-induced ototoxicity from compounds such as aminoglycosides and platinum can damage the inner ear resulting in hearing loss, tinnitus or balance problems and may be caused by the formation of reactive oxygen species (ROS). ...RESULTS: Gentamicin trea …
OBJECTIVES: Drug-induced ototoxicity from compounds such as aminoglycosides and platinum can damage the inner ear resulting in hea …
12 results