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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 2
1985 2
1986 1
1987 2
1989 5
1990 5
1991 1
1992 4
1993 7
1994 5
1995 5
1996 8
1997 7
1998 2
1999 6
2000 4
2001 6
2002 11
2003 7
2004 9
2005 11
2006 11
2007 17
2008 9
2009 5
2010 13
2011 21
2012 27
2013 30
2014 35
2015 24
2016 25
2017 34
2018 40
2019 75
2020 75
2021 59
2022 53
2023 8
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589 results
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Page 1
Epinephrine in Out-of-hospital Cardiac Arrest: Helpful or Harmful?
Shao H, Li CS. Shao H, et al. Chin Med J (Engl). 2017 Sep 5;130(17):2112-2116. doi: 10.4103/0366-6999.213429. Chin Med J (Engl). 2017. PMID: 28836556 Free PMC article. Review.
The evidence for the use of adrenaline in out-of-hospital cardiac arrest (OHCA) and in-hospital resuscitation is inconclusive. ...The American Heart Association recommends the use of epinephrine in patients with cardiac arrest
The evidence for the use of adrenaline in out-of-hospital cardiac arrest (OHCA) and in-hospital resuscita …
A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest.
Perkins GD, Ji C, Deakin CD, Quinn T, Nolan JP, Scomparin C, Regan S, Long J, Slowther A, Pocock H, Black JJM, Moore F, Fothergill RT, Rees N, O'Shea L, Docherty M, Gunson I, Han K, Charlton K, Finn J, Petrou S, Stallard N, Gates S, Lall R; PARAMEDIC2 Collaborators. Perkins GD, et al. N Engl J Med. 2018 Aug 23;379(8):711-721. doi: 10.1056/NEJMoa1806842. Epub 2018 Jul 18. N Engl J Med. 2018. PMID: 30021076 Free article. Clinical Trial.
BACKGROUND: Concern about the use of epinephrine as a treatment for out-of-hospital cardiac arrest led the International Liaison Committee on Resuscitation to call for a placebo-controlled trial to determine whether the use of epinephrine is saf …
BACKGROUND: Concern about the use of epinephrine as a treatment for out-of-hospital cardiac arrest led the Inter …
Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial.
Vallentin MF, Granfeldt A, Meilandt C, Povlsen AL, Sindberg B, Holmberg MJ, Iversen BN, Mærkedahl R, Mortensen LR, Nyboe R, Vandborg MP, Tarpgaard M, Runge C, Christiansen CF, Dissing TH, Terkelsen CJ, Christensen S, Kirkegaard H, Andersen LW. Vallentin MF, et al. JAMA. 2021 Dec 14;326(22):2268-2276. doi: 10.1001/jama.2021.20929. JAMA. 2021. PMID: 34847226 Free PMC article. Clinical Trial.
IMPORTANCE: It is unclear whether administration of calcium has a beneficial effect in patients with cardiac arrest. OBJECTIVE: To determine whether administration of calcium during out-of-hospital cardiac arrest improves return of spontaneous c …
IMPORTANCE: It is unclear whether administration of calcium has a beneficial effect in patients with cardiac arrest. OBJECTIVE …
Epinephrine versus norepinephrine in cardiac arrest patients with post-resuscitation shock.
Bougouin W, Slimani K, Renaudier M, Binois Y, Paul M, Dumas F, Lamhaut L, Loeb T, Ortuno S, Deye N, Voicu S, Beganton F, Jost D, Mekontso-Dessap A, Marijon E, Jouven X, Aissaoui N, Cariou A; Sudden Death Expertise Center Investigators. Bougouin W, et al. Intensive Care Med. 2022 Mar;48(3):300-310. doi: 10.1007/s00134-021-06608-7. Epub 2022 Feb 7. Intensive Care Med. 2022. PMID: 35129643
We assessed outcomes of patients with post-resuscitation shock after out-of-hospital cardiac arrest according to whether the continuous intravenous vasopressor used was epinephrine or norepinephrine. ...CONCLUSION: Among patients with post-resuscitatio …
We assessed outcomes of patients with post-resuscitation shock after out-of-hospital cardiac arrest according to whethe …
Capnography during cardiac arrest.
Sandroni C, De Santis P, D'Arrigo S. Sandroni C, et al. Resuscitation. 2018 Nov;132:73-77. doi: 10.1016/j.resuscitation.2018.08.018. Epub 2018 Aug 22. Resuscitation. 2018. PMID: 30142399 Review.
Successful resuscitation from cardiac arrest depends on provision of adequate blood flow to vital organs generated by cardiopulmonary resuscitation (CPR). Measurement of end-tidal expiratory pressure of carbon dioxide (ETCO(2)) using capnography provides a noninvasi …
Successful resuscitation from cardiac arrest depends on provision of adequate blood flow to vital organs generated by cardiopu …
Adrenaline to improve survival in out-of-hospital cardiac arrest: the PARAMEDIC2 RCT.
Perkins GD, Ji C, Achana F, Black JJ, Charlton K, Crawford J, de Paeztron A, Deakin C, Docherty M, Finn J, Fothergill RT, Gates S, Gunson I, Han K, Hennings S, Horton J, Khan K, Lamb S, Long J, Miller J, Moore F, Nolan J, O'Shea L, Petrou S, Pocock H, Quinn T, Rees N, Regan S, Rosser A, Scomparin C, Slowther A, Lall R. Perkins GD, et al. Health Technol Assess. 2021 Apr;25(25):1-166. doi: 10.3310/hta25250. Health Technol Assess. 2021. PMID: 33861194 Free PMC article. Clinical Trial.

SETTING: This trial was set in five NHS ambulance services in England and Wales. PARTICIPANTS: Adults treated for an out-of-hospital cardiac arrest were included. Patients were ineligible if they were pregnant, if they were aged < 16 years, if the cardi

SETTING: This trial was set in five NHS ambulance services in England and Wales. PARTICIPANTS: Adults treated for an out-of-hospital
Epinephrine dosing interval and neurological outcome in out-of-hospital cardiac arrest.
Fukuda T, Kaneshima H, Matsudaira A, Chinen T, Sekiguchi H, Ohashi-Fukuda N, Inokuchi R, Kukita I. Fukuda T, et al. Perfusion. 2022 Nov;37(8):835-846. doi: 10.1177/02676591211025163. Epub 2021 Jun 12. Perfusion. 2022. PMID: 34120526
OBJECTIVE: Current guidelines for cardiopulmonary resuscitation (CPR) recommend that standard-dose epinephrine be administered every 3-5 minutes during cardiac arrest. However, there is a knowledge gap regarding the optimal epinephrine dosing interval. …
OBJECTIVE: Current guidelines for cardiopulmonary resuscitation (CPR) recommend that standard-dose epinephrine be administered every …
Adrenaline and vasopressin for cardiac arrest.
Finn J, Jacobs I, Williams TA, Gates S, Perkins GD. Finn J, et al. Cochrane Database Syst Rev. 2019 Jan 17;1(1):CD003179. doi: 10.1002/14651858.CD003179.pub2. Cochrane Database Syst Rev. 2019. PMID: 30653257 Free PMC article.
OBJECTIVES: To determine whether adrenaline or vasopressin, or both, administered during cardiac arrest, afford any survival benefit. ...SELECTION CRITERIA: Any randomised controlled trial comparing: standard-dose adrenaline versus placebo; standard-do …
OBJECTIVES: To determine whether adrenaline or vasopressin, or both, administered during cardiac arrest, afford any sur …
Updates in Cardiac Arrest Resuscitation.
Lam V, Hsu CH. Lam V, et al. Emerg Med Clin North Am. 2020 Nov;38(4):755-769. doi: 10.1016/j.emc.2020.06.003. Epub 2020 Jul 30. Emerg Med Clin North Am. 2020. PMID: 32981615 Review.
There are approximately 350,000 out-of-hospital cardiac arrests and 200,000 in-hospital cardiac arrests annually in the United States, with survival rates of approximately 5% to 10% and 24%, respectively. ...This article focuses on current treatment re …
There are approximately 350,000 out-of-hospital cardiac arrests and 200,000 in-hospital cardiac arrests annually …
Treatment Outcomes of Epinephrine for Traumatic Out-of-hospital Cardiac Arrest: A Systematic Review and Meta-analysis.
Wongtanasarasin W, Thepchinda T, Kasirawat C, Saetiao S, Leungvorawat J, Kittivorakanchai N. Wongtanasarasin W, et al. J Emerg Trauma Shock. 2021 Oct-Dec;14(4):195-200. doi: 10.4103/JETS.JETS_35_21. Epub 2021 Nov 23. J Emerg Trauma Shock. 2021. PMID: 35125783 Free PMC article.
INTRODUCTION: Despite the standard guidelines stating that giving epinephrine for patients with cardiac arrest is recommended, the clinical benefits of epinephrine for patients with traumatic out-of-hospital cardiac arrest (OHCA) a …
INTRODUCTION: Despite the standard guidelines stating that giving epinephrine for patients with cardiac arrest is recom …
589 results