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Nutritional approaches to counter performance constraints in high-level sports competition.
Burke LM. Burke LM. Exp Physiol. 2021 Dec;106(12):2304-2323. doi: 10.1113/EP088188. Epub 2021 Nov 26. Exp Physiol. 2021. PMID: 34762329 Free PMC article. Review.
NEW FINDINGS: What is the topic of this review? The nutritional strategies that athletes use during competition events to optimize performance and the reasons they use them. ...A unifying model proposes that some scenarios require personalized fluid plans while others migh …
NEW FINDINGS: What is the topic of this review? The nutritional strategies that athletes use during competition events to optimize pe …
Physiology of Taste Processing in the Tongue, Gut, and Brain.
Gutierrez R, Simon SA. Gutierrez R, et al. Compr Physiol. 2021 Sep 23;11(4):2489-2523. doi: 10.1002/cphy.c210002. Compr Physiol. 2021. PMID: 34558667 Review.
Some of these have nutritive value (sugars, amino acids, salts, and fats) and are appetitive and avidly ingested, whereas others (atropine, quinine, nicotine) are aversive and rapidly rejected. However, the gustatory system is mainly responsible for evoking the perception …
Some of these have nutritive value (sugars, amino acids, salts, and fats) and are appetitive and avidly ingested, whereas others (atr …
TRPM8 Channels: Advances in Structural Studies and Pharmacological Modulation.
Izquierdo C, Martín-Martínez M, Gómez-Monterrey I, González-Muñiz R. Izquierdo C, et al. Int J Mol Sci. 2021 Aug 7;22(16):8502. doi: 10.3390/ijms22168502. Int J Mol Sci. 2021. PMID: 34445208 Free PMC article. Review.
The transient receptor potential melastatin subtype 8 (TRPM8) is a cold sensor in humans, activated by low temperatures (>10, <28 C), but also a polymodal ion channel, stimulated by voltage, pressure, cooling compounds (menthol, icilin), and hyperosmolarity. An incre …
The transient receptor potential melastatin subtype 8 (TRPM8) is a cold sensor in humans, activated by low temperatures (>10, <28 C), …
Medical Species Used in Russia for the Management of Diabetes and Related Disorders.
Shikov AN, Narkevich IA, Akamova AV, Nemyatykh OD, Flisyuk EV, Luzhanin VG, Povydysh MN, Mikhailova IV, Pozharitskaya ON. Shikov AN, et al. Front Pharmacol. 2021 Jul 20;12:697411. doi: 10.3389/fphar.2021.697411. eCollection 2021. Front Pharmacol. 2021. PMID: 34354589 Free PMC article. Review.
The information relevant to medical species, diabetes, and obesity was collected from local libraries, the online service E-library.ru, and Google Scholar. ...Haglund., Urtica dioica L., Rosa spp., Hypericum spp., Galega officinalis L., Mentha piperita L., Ar …
The information relevant to medical species, diabetes, and obesity was collected from local libraries, the online service E-library.r …
Medical aromatherapy in geriatric syndrome.
Ebihara T, Yamasaki M, Kozaki K, Ebihara S. Ebihara T, et al. Geriatr Gerontol Int. 2021 May;21(5):377-385. doi: 10.1111/ggi.14157. Epub 2021 Mar 31. Geriatr Gerontol Int. 2021. PMID: 33789361 Review.
To mitigate the intractable geriatric symptoms, we review the efficacy of aromatherapy, especially for dysphagia, dyspnea, cognitive dysfunction and falls in geriatric syndrome. ...Brain imaging study showed that olfactory stimulation using volatile black pepper oil activa …
To mitigate the intractable geriatric symptoms, we review the efficacy of aromatherapy, especially for dysphagia, dyspnea, cognitive …
Menthol to Induce Non-shivering Thermogenesis via TRPM8/PKA Signaling for Treatment of Obesity.
Sanders OD, Rajagopal JA, Rajagopal L. Sanders OD, et al. J Obes Metab Syndr. 2021 Mar 30;30(1):4-11. doi: 10.7570/jomes20038. J Obes Metab Syndr. 2021. PMID: 33071240 Free PMC article. Review.
In animals, TRPM8 agonism increases basal metabolic rate, non-shivering thermogenesis, oxygen consumption, exercise endurance, and fatty acid oxidation and decreases abdominal fat percentage. ...However, topical menthol appears to increas …
In animals, TRPM8 agonism increases basal metabolic rate, non-shivering thermogenesis, oxygen consumption, exercise end …
Acute Eosinophilic Pneumonia Secondary to Menthol Cigarette Use: A Rare Phenomenon With a Review of Literature.
Harne PS, Rao S, Malik M, Shepherd Z. Harne PS, et al. J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620925978. doi: 10.1177/2324709620925978. J Investig Med High Impact Case Rep. 2020. PMID: 32462944 Free PMC article. Review.
We present a case of a 31-year-old male who presented with 2 days of shortness of breath, cough, pleuritic chest pain, fevers, chills, nausea, and poor appetite in the setting of initiation of menthol-flavored cigarettes 2 weeks before presentation. ...One week late …
We present a case of a 31-year-old male who presented with 2 days of shortness of breath, cough, pleuritic chest pain, fevers, chills, nause …
Phytochemicals as potential candidates to combat obesity via adipose non-shivering thermogenesis.
Li H, Qi J, Li L. Li H, et al. Pharmacol Res. 2019 Sep;147:104393. doi: 10.1016/j.phrs.2019.104393. Epub 2019 Aug 8. Pharmacol Res. 2019. PMID: 31401211 Review.
Obesity is a chronic metabolic disease caused by a long-term imbalance between energy intake and expenditure. ...In this review, we summarize the mechanisms and strategies for targeting adipose-mediated thermogenesis and hig
Obesity is a chronic metabolic disease caused by a long-term imbalance between energy intake and expendit
Recent Progress in TRPM8 Modulation: An Update.
González-Muñiz R, Bonache MA, Martín-Escura C, Gómez-Monterrey I. González-Muñiz R, et al. Int J Mol Sci. 2019 May 28;20(11):2618. doi: 10.3390/ijms20112618. Int J Mol Sci. 2019. PMID: 31141957 Free PMC article. Review.
The transient receptor potential melastatin subtype 8 (TRPM8) is a nonselective, multimodal ion channel, activated by low temperatures (<28 C), pressure, and cooling compounds (menthol, icilin). Experimental evidences indicated a role of TRPM8 in cold thermal transducti …
The transient receptor potential melastatin subtype 8 (TRPM8) is a nonselective, multimodal ion channel, activated by low temperatures (< …
Food Ingredients Involved in White-to-Brown Adipose Tissue Conversion and in Calorie Burning.
El Hadi H, Di Vincenzo A, Vettor R, Rossato M. El Hadi H, et al. Front Physiol. 2019 Jan 11;9:1954. doi: 10.3389/fphys.2018.01954. eCollection 2018. Front Physiol. 2019. PMID: 30687134 Free PMC article. Review.
Obesity is the consequence of chronic positive energy balance and considered a leading risk factor for cardiovascular and metabolic diseases. Due to its epidemic trends among children and adults, there is an increasing interest in implementing new therapeutic
Obesity is the consequence of chronic positive energy balance and considered a leading risk factor for cardiovascular and m
Caraway as Important Medicinal Plants in Management of Diseases.
Mahboubi M. Mahboubi M. Nat Prod Bioprospect. 2019 Jan;9(1):1-11. doi: 10.1007/s13659-018-0190-x. Epub 2018 Oct 29. Nat Prod Bioprospect. 2019. PMID: 30374904 Free PMC article. Review.
Essential oil, fixed oil and many other valuable extractive compounds with industrial applications are prepared from caraway. This review article has new deep research on caraway as medicinal plant. ...Caraway oil in combination with peppermint oil or menthol
Essential oil, fixed oil and many other valuable extractive compounds with industrial applications are prepared from caraway. This review
L-Menthol attenuates the magnitude of cold-induced vasodilation on the extremities of young females.
Kim S, Lee JY. Kim S, et al. J Physiol Anthropol. 2018 May 9;37(1):14. doi: 10.1186/s40101-018-0174-x. J Physiol Anthropol. 2018. PMID: 29739454 Free PMC article. Clinical Trial.
BACKGROUND: Menthol chemically triggers cold-sensitive receptors in the skin without conductive skin cooling. ...A trial consisted of 10-min rest followed by 30-min immersion and 20-min recovery in 28 C air temperature with 20% relative humidity. Another trial without the …
BACKGROUND: Menthol chemically triggers cold-sensitive receptors in the skin without conductive skin cooling. ...A trial consisted of …
Precision Medicine for Tobacco Dependence: Development and Validation of the Nicotine Metabolite Ratio.
Allenby CE, Boylan KA, Lerman C, Falcone M. Allenby CE, et al. J Neuroimmune Pharmacol. 2016 Sep;11(3):471-83. doi: 10.1007/s11481-016-9656-y. Epub 2016 Feb 12. J Neuroimmune Pharmacol. 2016. PMID: 26872457 Free PMC article. Review.
In this review, we introduce the nicotine metabolite ratio (NMR) as a reliable and stable phenotypic measure of nicotine metabolism that can guide smoking cessation treatment among smokers who wish to quit. We address how the NMR accounts for sources of varia …
In this review, we introduce the nicotine metabolite ratio (NMR) as a reliable and stable phenotypic measure of nicotine me
Brown adipose tissue as a therapeutic target for human obesity.
Saito M. Saito M. Obes Res Clin Pract. 2013 Dec;7(6):e432-8. doi: 10.1016/j.orcp.2013.09.001. Obes Res Clin Pract. 2013. PMID: 24459687 Review.
Brown adipose tissue (BAT) is the major site of sympathetically activated adaptive thermogenesis during cold exposure and after spontaneous hyperphagia, thereby controlling whole-body energy expenditure and body fat. ...The inverse …
Brown adipose tissue (BAT) is the major site of sympathetically activated adaptive thermogenesis during cold exposure a …
Common gastrointestinal symptoms: irritable bowel syndrome.
Fashner J, Gitu AC. Fashner J, et al. FP Essent. 2013 Oct;413:16-23. FP Essent. 2013. PMID: 24124703 Review.
When evaluating patients with IBS, physicians should be alert for red flag symptoms, such as rectal bleeding, anemia, nighttime pain, and weight loss. Physicians also should consider other medical conditions that manifest similarly to IBS. ...Various etiologic mecha …
When evaluating patients with IBS, physicians should be alert for red flag symptoms, such as rectal bleeding, anemia, nighttime pain, and …
Herbal products use during pregnancy: prevalence and predictors.
Moussally K, Oraichi D, Bérard A. Moussally K, et al. Pharmacoepidemiol Drug Saf. 2009 Jun;18(6):454-61. doi: 10.1002/pds.1731. Pharmacoepidemiol Drug Saf. 2009. PMID: 19326360 Review.
Women were eligible if they were continuously insured by the RAMQ drug plan for at least 12 months before the first day of gestation and during pregnancy, and if they gave birth to a live born between January 1998 and December 2003 in one of the Quebec's hospitals. Women w …
Women were eligible if they were continuously insured by the RAMQ drug plan for at least 12 months before the first day of gestation and dur …
Possible effects on smokers of cigarette mentholation: a review of the evidence relating to key research questions.
Werley MS, Coggins CR, Lee PN. Werley MS, et al. Regul Toxicol Pharmacol. 2007 Mar;47(2):189-203. doi: 10.1016/j.yrtph.2006.09.004. Epub 2006 Nov 13. Regul Toxicol Pharmacol. 2007. PMID: 17097785 Review.
Despite its long usage history and GRAS status, scientific literature on effects of cigarette mentholation is limited. Because African-American men have high lung cancer rates and predominantly smoke mentholated cigarettes, and because menthol's coolin …
Despite its long usage history and GRAS status, scientific literature on effects of cigarette mentholation is limited. Because Africa …
The nicotine inhaler: clinical pharmacokinetics and comparison with other nicotine treatments.
Schneider NG, Olmstead RE, Franzon MA, Lunell E. Schneider NG, et al. Clin Pharmacokinet. 2001;40(9):661-84. doi: 10.2165/00003088-200140090-00003. Clin Pharmacokinet. 2001. PMID: 11605715 Review.
The potency of nicotine as the primary reinforcement in tobacco addiction is attributed to this rapid rate of delivery. By design, nicotine treatments reduce the rate and extent of drug delivery for weaning from nicotine during smoking cessation. ...Estimates of nic …
The potency of nicotine as the primary reinforcement in tobacco addiction is attributed to this rapid rate of delivery. By design, ni …
Role of cold receptors and menthol in thirst, the drive to breathe and arousal.
Eccles R. Eccles R. Appetite. 2000 Feb;34(1):29-35. doi: 10.1006/appe.1999.0291. Appetite. 2000. PMID: 10744889 Review.
Menthol has been shown to stimulate cold receptors in the mouth and nose. ...The satisfying effects of menthol on thirst and breathing, together with an effect on arousal, may explain the popularity of menthol and account for the very large amount of menth
Menthol has been shown to stimulate cold receptors in the mouth and nose. ...The satisfying effects of menthol on thirst and b
Nicotine metabolism variability and nicotine addiction.
Ahijevych K. Ahijevych K. Nicotine Tob Res. 1999;1 Suppl 2:S59-62; discussion S69-70. doi: 10.1080/14622299050011821. Nicotine Tob Res. 1999. PMID: 11768188
Individual variation in nicotine metabolism may play a role in a person's level of smoking, as well as in the transition from initiation to maintenance of a smoking behavior pattern. ...We do know that factors influencing the rate of nicotine metabo
Individual variation in nicotine metabolism may play a role in a person's level of smoking, as well as in the transition from …
Aspects of the epidemiology of lung cancer in smokers and nonsmokers in the United States.
Kabat GC. Kabat GC. Lung Cancer. 1996 Aug;15(1):1-20. doi: 10.1016/0169-5002(95)00566-8. Lung Cancer. 1996. PMID: 8865119 Review.
Data from a large, hospital-based case-control study are used to examine the association of smoking-related risk factors (amount smoked, filter status, mentholation, and differences in smoking habits between blacks and whites) and selected factors other than smoking (envir …
Data from a large, hospital-based case-control study are used to examine the association of smoking-related risk factors (amount smoked, fil …
Two-phase system membrane reactor with cofactor recycling.
Kise S, Hayashida M. Kise S, et al. J Biotechnol. 1990 May;14(2):221-8. doi: 10.1016/0168-1656(90)90011-y. J Biotechnol. 1990. PMID: 1366551 Review.
For the purpose of constructing a two-phase system reactor the enzymatic process of l-menthol production with cofactor recycling was studied as a model. ...The number of theoretical plates was calculated to be 40 for the separation of l-menthol from other reactants. …
For the purpose of constructing a two-phase system reactor the enzymatic process of l-menthol production with cofactor recycling was …