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1969 2
1970 3
1971 1
1972 2
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1974 3
1975 8
1976 4
1977 5
1978 5
1979 3
1980 2
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1982 4
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1985 3
1986 2
1987 2
1988 3
1990 2
1991 3
1993 3
1994 1
1995 6
1996 4
1997 4
1998 4
1999 4
2000 6
2001 10
2002 11
2003 10
2004 8
2005 13
2006 17
2007 19
2008 23
2009 23
2010 24
2011 25
2012 29
2013 22
2014 25
2015 21
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2017 25
2018 34
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614 results

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Page 1
Formulation, stabilisation and encapsulation of bacteriophage for phage therapy.
Malik DJ, Sokolov IJ, Vinner GK, Mancuso F, Cinquerrui S, Vladisavljevic GT, Clokie MRJ, Garton NJ, Stapley AGF, Kirpichnikova A. Malik DJ, et al. Adv Colloid Interface Sci. 2017 Nov;249:100-133. doi: 10.1016/j.cis.2017.05.014. Epub 2017 May 14. Adv Colloid Interface Sci. 2017. PMID: 28688779 Free article. Review.
Against a backdrop of global antibiotic resistance and increasing awareness of the importance of the human microbiota, there has been resurgent interest in the potential use of bacteriophages for therapeutic purposes, known as phage therapy. A number of phage …
Against a backdrop of global antibiotic resistance and increasing awareness of the importance of the human microbiota, there has been resurg …
Bacteriophages of the Human Gut: The "Known Unknown" of the Microbiome.
Shkoporov AN, Hill C. Shkoporov AN, et al. Cell Host Microbe. 2019 Feb 13;25(2):195-209. doi: 10.1016/j.chom.2019.01.017. Cell Host Microbe. 2019. PMID: 30763534 Free article. Review.
While the bacterial components of the microbiome have received considerable attention, comparatively little is known about the composition and physiological significance of human gut-associated bacteriophage populations (phageome). By extrapolating our knowledge of phag …
While the bacterial components of the microbiome have received considerable attention, comparatively little is known about the composition a …
Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials.
Bikard D, Euler CW, Jiang W, Nussenzweig PM, Goldberg GW, Duportet X, Fischetti VA, Marraffini LA. Bikard D, et al. Nat Biotechnol. 2014 Nov;32(11):1146-50. doi: 10.1038/nbt.3043. Epub 2014 Oct 5. Nat Biotechnol. 2014. PMID: 25282355 Free PMC article.
Antibiotics target conserved bacterial cellular pathways or growth functions and therefore cannot selectively kill specific members of a complex microbial population. Here, we develop programmable, sequence-specific antimicrobials using the RNA-guided nuclease Cas9 …
Antibiotics target conserved bacterial cellular pathways or growth functions and therefore cannot selectively kill specific members o …
Phage resistance in Klebsiella pneumoniae and bidirectional effects impacting antibiotic susceptibility.
Nang SC, Lu J, Yu HH, Wickremasinghe H, Azad MAK, Han M, Zhao J, Rao G, Bergen PJ, Velkov T, Sherry N, McCarthy DT, Aslam S, Schooley RT, Howden BP, Barr JJ, Zhu Y, Li J. Nang SC, et al. Clin Microbiol Infect. 2024 Jun;30(6):787-794. doi: 10.1016/j.cmi.2024.03.015. Epub 2024 Mar 22. Clin Microbiol Infect. 2024. PMID: 38522841
OBJECTIVES: Bacteriophage (phage) therapy is a promising anti-infective option to combat antimicrobial resistance. ...Phage resistance mechanisms were investigated with adsorption, one-step growth, and mutation frequency assays. ...
OBJECTIVES: Bacteriophage (phage) therapy is a promising anti-infective option to combat antimicrobial resistance. ...Phage …
Basic Phage Mathematics.
Abedon ST, Katsaounis TI. Abedon ST, et al. Methods Mol Biol. 2018;1681:3-30. doi: 10.1007/978-1-4939-7343-9_1. Methods Mol Biol. 2018. PMID: 29134583 Review.
Basic mathematical descriptions are useful in phage ecology, applied phage ecology such as in the course of phage therapy, and also toward keeping track of expected phage-bacterial interactions as seen during laboratory manipulation of phages. . …
Basic mathematical descriptions are useful in phage ecology, applied phage ecology such as in the course of phage thera …
Growth-Dependent Predation and Generalized Transduction of Antimicrobial Resistance by Bacteriophage.
Leclerc QJ, Wildfire J, Gupta A, Lindsay JA, Knight GM. Leclerc QJ, et al. mSystems. 2022 Apr 26;7(2):e0013522. doi: 10.1128/msystems.00135-22. Epub 2022 Mar 21. mSystems. 2022. PMID: 35311576 Free PMC article.
We developed multiple mathematical models of the bacteria and phage relationship and found that phage-bacteria dynamics were best captured by a model in which phage burst size decreases as the bacteria population reaches stationary phase and where p …
We developed multiple mathematical models of the bacteria and phage relationship and found that phage-bacteria dynamics were b …
Classification of In Vitro Phage-Host Population Growth Dynamics.
Sørensen PE, Ng DYK, Duchateau L, Ingmer H, Garmyn A, Butaye P. Sørensen PE, et al. Microorganisms. 2021 Nov 30;9(12):2470. doi: 10.3390/microorganisms9122470. Microorganisms. 2021. PMID: 34946072 Free PMC article.
However, the understanding of the phage-bacterium interactions and population dynamics seems essential for successful phage therapy implementation. Here, we investigated the effect of three factors: phage species (18 lytic E. coli-infecting phages …
However, the understanding of the phage-bacterium interactions and population dynamics seems essential for successful phage …
Bacteriophage secondary infection.
Abedon ST. Abedon ST. Virol Sin. 2015 Feb;30(1):3-10. doi: 10.1007/s12250-014-3547-2. Epub 2015 Jan 13. Virol Sin. 2015. PMID: 25595214 Free PMC article. Review.
Alternatively, and drawing from epidemiology, secondary infection has been used to describe phage population growth as that can occur during active phage therapy as well as upon phage contamination of industrial ferments. Here primary infections …
Alternatively, and drawing from epidemiology, secondary infection has been used to describe phage population growth as …
Freshwater cyanophages.
Xia H, Li T, Deng F, Hu Z. Xia H, et al. Virol Sin. 2013 Oct;28(5):253-9. doi: 10.1007/s12250-013-3370-1. Epub 2013 Sep 28. Virol Sin. 2013. PMID: 24132756 Free PMC article. Review.
They have a complex pattern of host ranges and play important roles in controlling cyanobacteria population. Unlike marine cyanophages, for which there have been a number of recent investigations, very little attention has been paid to freshwater cyanophages. ...
They have a complex pattern of host ranges and play important roles in controlling cyanobacteria population. Unlike marine cyanophage …
Preface.
Gao D, Ruan S, Jiang J. Gao D, et al. Math Biosci Eng. 2017 Oct/Dec 1;14(5-6):i-ii. doi: 10.3934/mbe.201705i. Math Biosci Eng. 2017. PMID: 29161850 Free article.
In the new century, with rapid population growth, large-scale urbanization, global warming and many other factors, we are facing unprecedented ecological, health, social, and other challenges and issues. These include biological invasion, environmental degradation, …
In the new century, with rapid population growth, large-scale urbanization, global warming and many other factors, we are faci …
614 results