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Quantitative and rapid Plasmodium falciparum malaria diagnosis and artemisinin-resistance detection using a CMOS Lab-on-Chip platform.
Malpartida-Cardenas K, Miscourides N, Rodriguez-Manzano J, Yu LS, Moser N, Baum J, Georgiou P. Malpartida-Cardenas K, et al. Biosens Bioelectron. 2019 Dec 1;145:111678. doi: 10.1016/j.bios.2019.111678. Epub 2019 Sep 7. Biosens Bioelectron. 2019. PMID: 31541787 Free PMC article.
Early and accurate diagnosis of malaria and drug-resistance is essential to effective disease management. ...This paper reports the specific, quantitative and fully-electronic detection of Plasmodium falciparum, the predominant malaria-causing parasite worldw …
Early and accurate diagnosis of malaria and drug-resistance is essential to effective disease management. ...This paper reports the s …
Allele-Specific Isothermal Amplification Method Using Unmodified Self-Stabilizing Competitive Primers.
Malpartida-Cardenas K, Rodriguez-Manzano J, Yu LS, Delves MJ, Nguon C, Chotivanich K, Baum J, Georgiou P. Malpartida-Cardenas K, et al. Anal Chem. 2018 Oct 16;90(20):11972-11980. doi: 10.1021/acs.analchem.8b02416. Epub 2018 Oct 2. Anal Chem. 2018. PMID: 30226760 Free PMC article.
We successfully validate our method by detecting SNPs, C580Y and Y493H, in the Plasmodium falciparum kelch 13 gene that are responsible for resistance to artemisinin-based combination therapies currently used globally in the treatment of malaria. ...
We successfully validate our method by detecting SNPs, C580Y and Y493H, in the Plasmodium falciparum kelch 13 gene that are responsib …