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Mitochondria: The ketogenic diet--A metabolism-based therapy.
Vidali S, Aminzadeh S, Lambert B, Rutherford T, Sperl W, Kofler B, Feichtinger RG. Vidali S, et al. Int J Biochem Cell Biol. 2015 Jun;63:55-9. doi: 10.1016/j.biocel.2015.01.022. Epub 2015 Feb 7. Int J Biochem Cell Biol. 2015. PMID: 25666556 Review.
The ketogenic diet is used therapeutically for pharmacoresistant epilepsy and for "rare diseases" of glucose metabolism (glucose transporter type 1 and pyruvate dehydrogenase deficiency). As metabolic reprogramming from oxidative phosphorylation toward increa …
The ketogenic diet is used therapeutically for pharmacoresistant epilepsy and for "rare diseases" of glucose metabolism (glucose transporter …
Dietary Treatments for Epilepsy.
Haridas B, Kossoff EH. Haridas B, et al. Neurol Clin. 2022 Nov;40(4):785-797. doi: 10.1016/j.ncl.2022.03.009. Epub 2022 Sep 28. Neurol Clin. 2022. PMID: 36270691 Review.
The diet has been shown to be an effective treatment of choice for Glut1 deficiency, pyruvate dehydrogenase deficiency, infantile spasms, and superrefractory status epilepticus among others. ...
The diet has been shown to be an effective treatment of choice for Glut1 deficiency, pyruvate dehydrogenase deficiency, …
Summary of recommendations for the management of infantile seizures: Task Force Report for the ILAE Commission of Pediatrics.
Wilmshurst JM, Gaillard WD, Vinayan KP, Tsuchida TN, Plouin P, Van Bogaert P, Carrizosa J, Elia M, Craiu D, Jovic NJ, Nordli D, Hirtz D, Wong V, Glauser T, Mizrahi EM, Cross JH. Wilmshurst JM, et al. Epilepsia. 2015 Aug;56(8):1185-97. doi: 10.1111/epi.13057. Epub 2015 Jun 30. Epilepsia. 2015. PMID: 26122601 Free article. Review.
The ketogenic diet is the treatment of choice for epilepsy related to glucose transporter 1 deficiency syndrome and pyruvate dehydrogenase deficiency (expert opinion, level U recommendation). The identification of patients as potential candidates for epilepsy …
The ketogenic diet is the treatment of choice for epilepsy related to glucose transporter 1 deficiency syndrome and pyruvate dehyd …
Pyruvate dehydrogenase deficiency: morphological and metabolic effects, creation of animal model to search for curative treatment.
Ebertowska A, Ludkiewicz B, Klejbor I, Melka N, Moryś J. Ebertowska A, et al. Folia Morphol (Warsz). 2020;79(2):191-197. doi: 10.5603/FM.a2020.0020. Epub 2020 Feb 19. Folia Morphol (Warsz). 2020. PMID: 32073132 Free article. Review.
Mutation in genes encoding subunits of PDC leads to pyruvate dehydrogenase deficiency. Abnormalities in PDC activity result in severe metabolic and brain malformations. For better understanding the development and mechanism of pyruvate dehydrogenase …
Mutation in genes encoding subunits of PDC leads to pyruvate dehydrogenase deficiency. Abnormalities in PDC activity re …
Ketogenic Diets in the Treatment of Epilepsy.
Elia M, Klepper J, Leiendecker B, Hartmann H. Elia M, et al. Curr Pharm Des. 2017;23(37):5691-5701. doi: 10.2174/1381612823666170809101517. Curr Pharm Des. 2017. PMID: 28799513 Review.
Clinical Therapeutic Management of Human Mitochondrial Disorders.
Finsterer J. Finsterer J. Pediatr Neurol. 2020 Dec;113:66-74. doi: 10.1016/j.pediatrneurol.2020.07.004. Epub 2020 Jul 6. Pediatr Neurol. 2020. PMID: 33053453 Review.
Specific treatment can be offered for stroke-like episodes, mitochondrial epilepsy, mitochondrial neurogastrointestinal encephalopathy, Leber hereditary optic neuropathy, thiamine-responsive Leigh syndrome, primary coenzyme Q deficiency, primary carnitine deficiency, Friedreich a …
Specific treatment can be offered for stroke-like episodes, mitochondrial epilepsy, mitochondrial neurogastrointestinal encephalopathy, Lebe …
Ketogenic diet and childhood neurological disorders other than epilepsy: an overview.
Verrotti A, Iapadre G, Pisano S, Coppola G. Verrotti A, et al. Expert Rev Neurother. 2017 May;17(5):461-473. doi: 10.1080/14737175.2017.1260004. Epub 2016 Nov 21. Expert Rev Neurother. 2017. PMID: 27841033 Review.
Expert commentary: The role of KD in reducing seizure activity in some mitochondriopathies and its efficacy in pyruvate dehydrogenase deficiency is known. Recently, few cases suggest the potentiality of KD in decreasing paroxysmal activity in children affecte …
Expert commentary: The role of KD in reducing seizure activity in some mitochondriopathies and its efficacy in pyruvate dehydrogen …
Ketogenic Diet: A New Light Shining on Old but Gold Biochemistry.
Longo R, Peri C, Cricrì D, Coppi L, Caruso D, Mitro N, De Fabiani E, Crestani M. Longo R, et al. Nutrients. 2019 Oct 17;11(10):2497. doi: 10.3390/nu11102497. Nutrients. 2019. PMID: 31627352 Free PMC article. Review.
Ketogenic diets (KD) are currently used to treat different forms of infantile epilepsy, also caused by genetic defects such as Glut1 and Pyruvate Dehydrogenase Deficiency Syndromes. However, several researchers are now focusing on the possibility to use KD in …
Ketogenic diets (KD) are currently used to treat different forms of infantile epilepsy, also caused by genetic defects such as Glut1 and …
39 results