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Birth prevalence of omphalocele and gastroschisis in Sub-Saharan Africa: A systematic review and meta-analysis.
Tiruneh C, Gebremeskel T, Necho M, Teshome Y, Teshome D, Belete A. Tiruneh C, et al. SAGE Open Med. 2022 Sep 20;10:20503121221125536. doi: 10.1177/20503121221125536. eCollection 2022. SAGE Open Med. 2022. PMID: 36161211 Free PMC article. Review.
The pooled prevalence of major abdominal wall defects was estimated using a weighted inverse variance random-effects model. ...Fourteen articles that met the eligibility criteria were selected for this meta-analysis with 242,462 total enrolled particip …
The pooled prevalence of major abdominal wall defects was estimated using a weighted inverse variance random-effects model. .. …
Global population attributable fraction of potentially modifiable risk factors for mental disorders: a meta-umbrella systematic review.
Dragioti E, Radua J, Solmi M, Arango C, Oliver D, Cortese S, Jones PB, Il Shin J, Correll CU, Fusar-Poli P. Dragioti E, et al. Mol Psychiatry. 2022 Aug;27(8):3510-3519. doi: 10.1038/s41380-022-01586-8. Epub 2022 Apr 28. Mol Psychiatry. 2022. PMID: 35484237 Free PMC article.
The primary outcome was the global meta-analytical PAF, complemented by sensitivity analyses across different settings, the meta-analytical Generalised Impact Fraction (GIF), and study quality assessment (AMSTAR). ...The largest global PAFs not confounded by indicat …
The primary outcome was the global meta-analytical PAF, complemented by sensitivity analyses across different settings, the meta …
Effects of Psychotherapy on Quality of Life in End-stage Renal Disease Patients: A Systematic Review with Meta-analysis.
Phang K, Abdul Latif AAL, Lee KW, Ching SM, Ooi PB. Phang K, et al. Oman Med J. 2022 May 31;37(3):e383. doi: 10.5001/omj.2021.88. eCollection 2022 May. Oman Med J. 2022. PMID: 35712372 Free PMC article. Review.
Two researchers independently extracted articles that met the selection criteria and evaluated the quality of each study. A random-effects meta-analysis was conducted, and data was presented in weighted mean difference (WMD) with a 95% CI. RESULTS: Eight stud …
Two researchers independently extracted articles that met the selection criteria and evaluated the quality of each study. A random-effects …
Making Specific Plan Improves Physical Activity and Healthy Eating for Community-Dwelling Patients With Chronic Conditions: A Systematic Review and Meta-Analysis.
Lin H, Yu P, Yang M, Wu D, Wang Z, An J, Duan H, Deng N. Lin H, et al. Front Public Health. 2022 May 19;10:721223. doi: 10.3389/fpubh.2022.721223. eCollection 2022. Front Public Health. 2022. PMID: 35664117 Free PMC article.
Random-effects meta-analysis was conducted to estimate effect sizes of implementation intention on outcomes, including PA, DB, weight, and body mass index. And the eligible studies were assessed by the Cochrane Collaboration's tool …
Random-effects meta-analysis was conducted to estimate effect sizes of implementation intention on outcomes, including PA, DB, …
Body Mass Index and Mild Cognitive Impairment Among Middle-Aged and Older Adults from Low- and Middle-Income Countries.
Smith L, Shin JI, Oh H, Carmichael C, Jacob L, Stefanac S, Lindsay RK, Soysal P, Veronese N, Tully MA, Butler L, Barnett Y, Koyanagi A. Smith L, et al. J Alzheimers Dis. 2022;85(3):1095-1105. doi: 10.3233/JAD-215345. J Alzheimers Dis. 2022. PMID: 34897093
OBJECTIVE: The aim of the present study was to investigate the association between body mass index (BMI) status with mild cognitive impairment (MCI) (a preclinical stage of dementia) in middle-aged and older adults residing in six low- and middle-incom …
OBJECTIVE: The aim of the present study was to investigate the association between body mass index (BMI) status …
The Genetic Architecture of Depression in Individuals of East Asian Ancestry: A Genome-Wide Association Study.
Giannakopoulou O, Lin K, Meng X, Su MH, Kuo PH, Peterson RE, Awasthi S, Moscati A, Coleman JRI, Bass N, Millwood IY, Chen Y, Chen Z, Chen HC, Lu ML, Huang MC, Chen CH, Stahl EA, Loos RJF, Mullins N, Ursano RJ, Kessler RC, Stein MB, Sen S, Scott LJ, Burmeister M, Fang Y, Tyrrell J, Jiang Y, Tian C, McIntosh AM, Ripke S, Dunn EC, Kendler KS, Walters RG, Lewis CM, Kuchenbaecker K; 23andMe Research Team, China Kadoorie Biobank Collaborative Group, and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Giannakopoulou O, et al. JAMA Psychiatry. 2021 Nov 1;78(11):1258-1269. doi: 10.1001/jamapsychiatry.2021.2099. JAMA Psychiatry. 2021. PMID: 34586374 Free PMC article.
Another locus at 7p21.2 was associated in a meta-analysis restricted to geographically East Asian studies (beta = 0.028, SE = 0.005, P = 6.48x10-9 for rs10240457). ...Clinical depression risk was negatively genetically correlated with body mass inde …
Another locus at 7p21.2 was associated in a meta-analysis restricted to geographically East Asian studies (beta = 0.028, SE = …
Impact of body mass index on pathological complete response following neoadjuvant chemotherapy in operable breast cancer: a meta-analysis.
Wang H, Zhang S, Yee D, Basu S, Beckwith H, Potter D, Blaes A. Wang H, et al. Breast Cancer. 2021 May;28(3):618-629. doi: 10.1007/s12282-020-01194-w. Epub 2021 Jan 2. Breast Cancer. 2021. PMID: 33387284
PURPOSE: The impact of an increased body mass index (BMI) on outcomes of neoadjuvant chemotherapy (NACT) in breast cancer remains controversial. ...CONCLUSIONS: Overweight and obese breast cancer patients had a lower pCR rate with …
PURPOSE: The impact of an increased body mass index (BMI) on outcomes of neoadjuvant chemotherapy (NACT) in brea …
Association of maternal lipid profile and gestational diabetes mellitus: A systematic review and meta-analysis of 292 studies and 97,880 women.
Hu J, Gillies CL, Lin S, Stewart ZA, Melford SE, Abrams KR, Baker PN, Khunti K, Tan BK. Hu J, et al. EClinicalMedicine. 2021 Apr 16;34:100830. doi: 10.1016/j.eclinm.2021.100830. eCollection 2021 Apr. EClinicalMedicine. 2021. PMID: 33997732 Free PMC article.
FINDINGS: A total of 292 studies, comprising of 97,880 pregnant women (28232 GDM and 69,648 controls) were included. Using random-effects meta-analysis models to pool study estimates, women with GDM had significantly higher (by 20%) TG levels, with a pooled weigh …
FINDINGS: A total of 292 studies, comprising of 97,880 pregnant women (28232 GDM and 69,648 controls) were included. Using random-effects …
Simvastatin add-on to escitalopram in patients with comorbid obesity and major depression (SIMCODE): study protocol of a multicentre, randomised, double-blind, placebo-controlled trial.
Otte C, Chae WR, Nowacki J, Kaczmarczyk M, Piber D, Roepke S, Märschenz S, Lischewski S, Schmidt S, Ettrich B, Grabe HJ, Hegerl U, Hinkelmann K, Hofmann T, Janowitz D, Junghanns K, Kahl KG, Klein JP, Krueger THC, Leicht G, Prvulovic D, Reif A, Schoettle D, Strauss M, Westermair A, Friede T, Gold SM. Otte C, et al. BMJ Open. 2020 Dec 1;10(12):e040119. doi: 10.1136/bmjopen-2020-040119. BMJ Open. 2020. PMID: 33262189 Free PMC article.
INTRODUCTION: Major depressive disorder (MDD) and obesity are both common disorders associated with significant burden of disease worldwide. ...Statins are recommended in primary prevention of cardiovascular disease, which has been linked to both MDD and o …
INTRODUCTION: Major depressive disorder (MDD) and obesity are both common disorders associated with significant burden of disease …
The effect of teacher-delivered nutrition education programs on elementary-aged students: An updated systematic review and meta-analysis.
Cotton W, Dudley D, Peralta L, Werkhoven T. Cotton W, et al. Prev Med Rep. 2020 Aug 13;20:101178. doi: 10.1016/j.pmedr.2020.101178. eCollection 2020 Dec. Prev Med Rep. 2020. PMID: 32944494 Free PMC article.
This is concerning, considering the view that teachers are the key agents for promoting health and nutrition within schools. The purpose of the updated systematic review and meta-analysis was to ascertain the impact that nutrition education programs have on elementa …
This is concerning, considering the view that teachers are the key agents for promoting health and nutrition within schools. The purpose of …
Eating versus skipping breakfast has no discernible effect on obesity-related anthropometric outcomes: a systematic review and meta-analysis.
Bohan Brown MM, Milanes JE, Allison DB, Brown AW. Bohan Brown MM, et al. F1000Res. 2020 Feb 24;9:140. doi: 10.12688/f1000research.22424.2. eCollection 2020. F1000Res. 2020. PMID: 35340783 Free PMC article.
Mean differences were synthesized using inverse variance random effects meta-analysis for each outcome. Positive estimates indicate higher outcomes in breakfast conditions (e.g., weight gain). ...Conditions included recommendations to eat versus skip breakfas …
Mean differences were synthesized using inverse variance random effects meta-analysis for each outcome. Positive estimates ind …
Cold Application on Bruising at the Subcutaneous Heparin Injection Site: A Systematic Review and Meta-Analysis.
Amaniyan S, Ghobadi A, Vaismoradi M. Amaniyan S, et al. SAGE Open Nurs. 2020 Jan 20;6:2377960820901370. doi: 10.1177/2377960820901370. eCollection 2020 Jan-Dec. SAGE Open Nurs. 2020. PMID: 33415265 Free PMC article. Review.
This study sought to systematically assess current evidence regarding the effect of cold application as a fundamental nursing intervention on the occurrence and size of bruising at the injection site in patients receiving subcutaneous heparin. A systematic review and meta- …
This study sought to systematically assess current evidence regarding the effect of cold application as a fundamental nursing intervention o …
Longitudinal epigenome-wide association studies of three male military cohorts reveal multiple CpG sites associated with post-traumatic stress disorder.
Snijders C, Maihofer AX, Ratanatharathorn A, Baker DG, Boks MP, Geuze E, Jain S, Kessler RC, Pishva E, Risbrough VB, Stein MB, Ursano RJ, Vermetten E, Vinkers CH; PGC PTSD EWAS Consortium; Smith AK, Uddin M, Rutten BPF, Nievergelt CM. Snijders C, et al. Clin Epigenetics. 2020 Jan 13;12(1):11. doi: 10.1186/s13148-019-0798-7. Clin Epigenetics. 2020. PMID: 31931860 Free PMC article.
The Psychiatric Genomics Consortium (PGC) PTSD EWAS QC pipeline was used on all cohorts, and results were combined using a sample size weighted meta-analysis in a two-stage design. In stage one, we jointly analyzed data of two new cohorts (N = 126 and 78) for …
The Psychiatric Genomics Consortium (PGC) PTSD EWAS QC pipeline was used on all cohorts, and results were combined using a sample size we …
Genome-wide association study identifies 30 loci associated with bipolar disorder.
Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, Pers TH, Holmans PA, Richards AL, Abbott L, Agerbo E, Akil H, Albani D, Alliey-Rodriguez N, Als TD, Anjorin A, Antilla V, Awasthi S, Badner JA, Bækvad-Hansen M, Barchas JD, Bass N, Bauer M, Belliveau R, Bergen SE, Pedersen CB, Bøen E, Boks MP, Boocock J, Budde M, Bunney W, Burmeister M, Bybjerg-Grauholm J, Byerley W, Casas M, Cerrato F, Cervantes P, Chambert K, Charney AW, Chen D, Churchhouse C, Clarke TK, Coryell W, Craig DW, Cruceanu C, Curtis D, Czerski PM, Dale AM, de Jong S, Degenhardt F, Del-Favero J, DePaulo JR, Djurovic S, Dobbyn AL, Dumont A, Elvsåshagen T, Escott-Price V, Fan CC, Fischer SB, Flickinger M, Foroud TM, Forty L, Frank J, Fraser C, Freimer NB, Frisén L, Gade K, Gage D, Garnham J, Giambartolomei C, Pedersen MG, Goldstein J, Gordon SD, Gordon-Smith K, Green EK, Green MJ, Greenwood TA, Grove J, Guan W, Guzman-Parra J, Hamshere ML, Hautzinger M, Heilbronner U, Herms S, Hipolito M, Hoffmann P, Holland D, Huckins L, Jamain S, Johnson JS, Juréus A, Kandaswamy R, Karlsson R, Kennedy JL, Kitt… See abstract for full author list ➔ Stahl EA, et al. Nat Genet. 2019 May;51(5):793-803. doi: 10.1038/s41588-019-0397-8. Epub 2019 May 1. Nat Genet. 2019. PMID: 31043756 Free PMC article.

We performed a genome-wide association study (GWAS) including 20,352 cases and 31,358 controls of European descent, with follow-up analysis of 822 variants with P < 1 10(-4) in an additional 9,412 cases and 137,760 controls. ...In the combined analysis, 30 loci w

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We performed a genome-wide association study (GWAS) including 20,352 cases and 31,358 controls of European descent, with follow-up analys …
Association between smoking and non-alcoholic fatty liver disease: A systematic review and meta-analysis.
Akhavan Rezayat A, Dadgar Moghadam M, Ghasemi Nour M, Shirazinia M, Ghodsi H, Rouhbakhsh Zahmatkesh MR, Tavakolizadeh Noghabi M, Hoseini B, Akhavan Rezayat K. Akhavan Rezayat A, et al. SAGE Open Med. 2018 Jan 24;6:2050312117745223. doi: 10.1177/2050312117745223. eCollection 2018. SAGE Open Med. 2018. PMID: 29399359 Free PMC article.
The main goal of this systematic review and meta-analysis is to investigate the association between smoking and non-alcoholic fatty liver disease. ...CONCLUSION: Our meta-analysis demonstrated that smoking is significantly associated with non-al …
The main goal of this systematic review and meta-analysis is to investigate the association between smoking and non-alcoholic …
Genetic variants in the CPNE5 gene are associated with alcohol dependence and obesity in Caucasian populations.
Wang KS, Zuo L, Pan Y, Xie C, Luo X. Wang KS, et al. J Psychiatr Res. 2015 Dec;71:1-7. doi: 10.1016/j.jpsychires.2015.09.008. Epub 2015 Sep 14. J Psychiatr Res. 2015. PMID: 26522866
The Marshfield sample (1442 obese cases and 2122 non-obese controls) was used for replication of obesity. Multiple logistic regression analysis was performed using the PLINK software. In the SAGE sample, we identified 10 SNPs associated with AD …
The Marshfield sample (1442 obese cases and 2122 non-obese controls) was used for replication of obesity. Multiple logi …
A systematic review and meta-analysis of plasma amyloid 1-42 and tau as biomarkers for Alzheimer's disease.
Shanthi KB, Krishnan S, Rani P. Shanthi KB, et al. SAGE Open Med. 2015 Aug 10;3:2050312115598250. doi: 10.1177/2050312115598250. eCollection 2015. SAGE Open Med. 2015. PMID: 26770797 Free PMC article. Review.
A meta-analysis was performed to statistically validate the use of plasma Abeta42 and tau as biomarkers for Alzheimer's disease. ...CONCLUSION: This analysis pinpoints that plasma Abeta42 and tau could not serve as reliable markers independently …
A meta-analysis was performed to statistically validate the use of plasma Abeta42 and tau as biomarkers for Alzheimer's …
Effectiveness and safety of patient activation interventions for adults with type 2 diabetes: systematic review, meta-analysis, and meta-regression.
Bolen SD, Chandar A, Falck-Ytter C, Tyler C, Perzynski AT, Gertz AM, Sage P, Lewis S, Cobabe M, Ye Y, Menegay M, Windish DM. Bolen SD, et al. J Gen Intern Med. 2014 Aug;29(8):1166-76. doi: 10.1007/s11606-014-2855-4. Epub 2014 Apr 15. J Gen Intern Med. 2014. PMID: 24733301 Free PMC article. Review.
For all-cause mortality, we calculated the pooled odds ratio (OR) using Peto's method. We assessed statistical heterogeneity using the I (2) statistic and conducted meta-regression using a random-effects model when I (2) > 50 %. ...RESULTS: PAIs modestly r …
For all-cause mortality, we calculated the pooled odds ratio (OR) using Peto's method. We assessed statistical heterogeneity u …
A statin-dependent QTL for GATM expression is associated with statin-induced myopathy.
Mangravite LM, Engelhardt BE, Medina MW, Smith JD, Brown CD, Chasman DI, Mecham BH, Howie B, Shim H, Naidoo D, Feng Q, Rieder MJ, Chen YD, Rotter JI, Ridker PM, Hopewell JC, Parish S, Armitage J, Collins R, Wilke RA, Nickerson DA, Stephens M, Krauss RM. Mangravite LM, et al. Nature. 2013 Oct 17;502(7471):377-80. doi: 10.1038/nature12508. Epub 2013 Aug 28. Nature. 2013. PMID: 23995691 Free PMC article.
Statins are prescribed widely to lower plasma low-density lipoprotein (LDL) concentrations and cardiovascular disease risk and have been shown to have beneficial effects in a broad range of patients. ...We found this locus to be associated with incidence of statin-induced …
Statins are prescribed widely to lower plasma low-density lipoprotein (LDL) concentrations and cardiovascular disease risk and have b …
Genetic variants in the fat mass- and obesity-associated (FTO) gene are associated with alcohol dependence.
Wang L, Liu X, Luo X, Zeng M, Zuo L, Wang KS. Wang L, et al. J Mol Neurosci. 2013 Oct;51(2):416-24. doi: 10.1007/s12031-013-0044-2. Epub 2013 Jun 16. J Mol Neurosci. 2013. PMID: 23771786
Variants (such as rs9939609) in the fat mass- and obesity-associated (FTO) gene have been associated with obesity, type 2 diabetes, some cancers, and alcohol consumption. ...Haplotype analysis in the SAGE sample further supported the asso …
Variants (such as rs9939609) in the fat mass- and obesity-associated (FTO) gene have been associated with obesity …
A novel locus for body mass index on 5p15.2: a meta-analysis of two genome-wide association studies.
Wang KS, Liu X, Zheng S, Zeng M, Pan Y, Callahan K. Wang KS, et al. Gene. 2012 May 25;500(1):80-4. doi: 10.1016/j.gene.2012.03.046. Epub 2012 Mar 16. Gene. 2012. PMID: 22446040
OBJECTIVE: Genetic factors play an important role in modulating the vulnerability to body mass index (BMI). The purpose of this study is to identify novel genetic variants for BMI using genome-wide association (GWA) meta-analysis. …
OBJECTIVE: Genetic factors play an important role in modulating the vulnerability to body mass index (BMI). The …
The effect of type of physical activity measure on the relationship between body fatness and habitual physical activity in children: a meta-analysis.
Rowlands AV, Ingledew DK, Eston RG. Rowlands AV, et al. Ann Hum Biol. 2000 Sep-Oct;27(5):479-97. doi: 10.1080/030144600419314. Ann Hum Biol. 2000. PMID: 11023118

Mean effect sizes differed significantly (F(3,52) = 8.04, p < 0.001) according to the activity measure used: questionnaire, r = -0.14; motion counters, r = -0.18; observation, r = -0.39; heart rate (HR), r = 0.00. Observation measures elicited a significantly str

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Mean effect sizes differed significantly (F(3,52) = 8.04, p < 0.001) according to the activity measure used: questionnaire, r = -0.14; mo

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