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Year Number of Results
2016 5
2017 2
2018 3
2019 4
2020 4
2021 3
2022 2
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2024 4
2026 0

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26 results

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Page 1
TRIM21-mediated ubiquitylation of TAT suppresses liver metastasis in gallbladder cancer.
Wu Z, Zhang J, Jia Z, Yang Z, Liu S, Wang H, Zhao C, Zhao J, Tang Q, Xiong Y, Yang Y, Zhang Y, Zhou Z, Yue J, Xiao F, Sun Q, Gong A, Yao W, Li H, Song X, Ye Y, Zhu Y, Dong P, Ma F, Wu X, Gong W. Wu Z, et al. Cancer Lett. 2024 Jun 28;592:216923. doi: 10.1016/j.canlet.2024.216923. Epub 2024 May 1. Cancer Lett. 2024. PMID: 38697462
However, the mechanisms underlying liver metastasis remain largely unknown. Here, we report a crucial role of tyrosine aminotransferase (TAT) in liver metastasis of GBC. TAT is frequently up-regulated in GBC tissues. ...
However, the mechanisms underlying liver metastasis remain largely unknown. Here, we report a crucial role of tyrosine aminotransf …
The mutation spectrum and ethnic distribution of non-hepatorenal tyrosinemia (types II, III).
Beyzaei Z, Nabavizadeh S, Karimzadeh S, Geramizadeh B. Beyzaei Z, et al. Orphanet J Rare Dis. 2022 Dec 5;17(1):424. doi: 10.1186/s13023-022-02579-0. Orphanet J Rare Dis. 2022. PMID: 36471409 Free PMC article. Review.
Tyrosinemia type II and III are autosomal recessive disorders caused by pathogenic variants in the tyrosine aminotransferase (TAT), and 4-hydroxyphenyl-pyruvate dioxygenas (HPPD) genes, respectively. ...
Tyrosinemia type II and III are autosomal recessive disorders caused by pathogenic variants in the tyrosine aminotransferase ( …
Species differences and human relevance of the toxicity of 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitors and a new approach method in vitro for investigation.
Botham J, Lewis RW, Travis KZ, Baze A, Richert L, Codrea E, Semino Beninel G, Garcin JC, Strupp C. Botham J, et al. Arch Toxicol. 2023 Apr;97(4):991-999. doi: 10.1007/s00204-023-03458-8. Epub 2023 Feb 17. Arch Toxicol. 2023. PMID: 36800004 Free PMC article.
What is less well accepted is the basis for the marked difference in the effects of HPPD inhibitors that has been observed across experimental species and humans, where some species show significant toxicities whereas in other species exposure causes few effects. The activity of …
What is less well accepted is the basis for the marked difference in the effects of HPPD inhibitors that has been observed across experiment …
An Infant with Bilateral Keratitis: From Infectious to Genetic Diagnosis.
Thibault LP, Mitchell GA, Parisien B, Hamel P, Blanchard AC. Thibault LP, et al. Am J Case Rep. 2022 Nov 30;23:e937967. doi: 10.12659/AJCR.937967. Am J Case Rep. 2022. PMID: 36447403 Free PMC article.
BACKGROUND Tyrosinemia Type II (TYRII) is a rare autosomal recessive inborn error of metabolism caused by deficiency of tyrosine aminotransferase (TAT), leading to hypertyrosinemia. TYRII patients often present in the first year of life with ocular and cutaneous fin …
BACKGROUND Tyrosinemia Type II (TYRII) is a rare autosomal recessive inborn error of metabolism caused by deficiency of tyrosine a …
Targeting glioma-initiating cells via the tyrosine metabolic pathway.
Yamashita D, Bernstock JD, Elsayed G, Sadahiro H, Mohyeldin A, Chagoya G, Ilyas A, Mooney J, Estevez-Ordonez D, Yamaguchi S, Flanary VL, Hackney JR, Bhat KP, Kornblum HI, Zamboni N, Kim SH, Chiocca EA, Nakano I. Yamashita D, et al. J Neurosurg. 2020 Feb 14;134(3):721-732. doi: 10.3171/2019.11.JNS192028. Print 2021 Mar 1. J Neurosurg. 2020. PMID: 32059178 Free PMC article.
Furthermore, activation of the enzyme tyrosine aminotransferase (TAT) within the tyrosine metabolic pathway influenced the noted therapeutic resistance of the GBM core. ...
Furthermore, activation of the enzyme tyrosine aminotransferase (TAT) within the tyrosine metabolic pathway influenced the not …
Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis.
Sterkel M, Haines LR, Casas-Sánchez A, Owino Adung'a V, Vionette-Amaral RJ, Quek S, Rose C, Silva Dos Santos M, García Escude N, Ismail HM, Paine MI, Barribeau SM, Wagstaff S, MacRae JI, Masiga D, Yakob L, Oliveira PL, Acosta-Serrano Á. Sterkel M, et al. PLoS Biol. 2021 Jan 26;19(1):e3000796. doi: 10.1371/journal.pbio.3000796. eCollection 2021 Jan. PLoS Biol. 2021. PMID: 33497373 Free PMC article.
RNA interference (RNAi) of either the first two enzymes in the tyrosine degradation pathway (tyrosine aminotransferase (TAT) and 4-hydroxyphenylpyruvate dioxygenase (HPPD)) was lethal to tsetse. ...
RNA interference (RNAi) of either the first two enzymes in the tyrosine degradation pathway (tyrosine aminotransferase (TAT) a …
Unveiling prognostics biomarkers of tyrosine metabolism reprogramming in liver cancer by cross-platform gene expression analyses.
Nguyen TN, Nguyen HQ, Le DH. Nguyen TN, et al. PLoS One. 2020 Jun 15;15(6):e0229276. doi: 10.1371/journal.pone.0229276. eCollection 2020. PLoS One. 2020. PMID: 32542016 Free PMC article.
Abnormal expression of the tyrosine catabolic enzyme tyrosine aminotransferase (TAT) has been reported in patients with hepatocellular carcinoma (HCC). ...
Abnormal expression of the tyrosine catabolic enzyme tyrosine aminotransferase (TAT) has been reported in patients with hepato …
Mapping N- and C-terminals of Leishmania donovani tyrosine aminotransferase by gene truncation strategy: a functional study using in vitro and in silico approaches.
Sasidharan S, Saudagar P. Sasidharan S, et al. Sci Rep. 2020 Jul 27;10(1):12463. doi: 10.1038/s41598-020-69512-y. Sci Rep. 2020. PMID: 32719483 Free PMC article.
Tyrosine aminotransferase (TAT) catalyzes the transamination of amino acids in Leishmania sp.. ...
Tyrosine aminotransferase (TAT) catalyzes the transamination of amino acids in Leishmania sp.. ...
Lack of miR-133a Decreases Contractility of Diabetic Hearts: A Role for Novel Cross Talk Between Tyrosine Aminotransferase and Tyrosine Hydroxylase.
Nandi SS, Zheng H, Sharma NM, Shahshahan HR, Patel KP, Mishra PK. Nandi SS, et al. Diabetes. 2016 Oct;65(10):3075-90. doi: 10.2337/db16-0023. Epub 2016 Jul 13. Diabetes. 2016. PMID: 27411382 Free PMC article.
NE is synthesized from tyrosine by the rate-limiting enzyme, tyrosine hydroxylase (TH), and tyrosine is catabolized by tyrosine aminotransferase (TAT). However, the cross talk/link between TAT and TH in the heart is unclear. ...
NE is synthesized from tyrosine by the rate-limiting enzyme, tyrosine hydroxylase (TH), and tyrosine is catabolized by tyrosine am …
Concerted motion of structure and active site charge is required for tyrosine aminotransferase activity in Leishmania parasite.
Sasidharan S, Saudagar P. Sasidharan S, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2020 May 5;232:118133. doi: 10.1016/j.saa.2020.118133. Epub 2020 Feb 5. Spectrochim Acta A Mol Biomol Spectrosc. 2020. PMID: 32086045
Leishmania donovani tyrosine aminotransferase (LdTAT) is an essential enzyme that catalyzes the first step of amino acid catabolism. ...
Leishmania donovani tyrosine aminotransferase (LdTAT) is an essential enzyme that catalyzes the first step of amino acid catab …
26 results