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Year Number of Results
2011 1
2014 2
2015 1
2016 2
2017 1
2018 1
2019 1
2020 0
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Page 1
Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan.
Baker DJ, Childs BG, Durik M, Wijers ME, Sieben CJ, Zhong J, Saltness RA, Jeganathan KB, Verzosa GC, Pezeshki A, Khazaie K, Miller JD, van Deursen JM. Baker DJ, et al. Among authors: Childs BG, van Deursen JM. Nature. 2016 Feb 11;530(7589):184-9. doi: 10.1038/nature16932. Epub 2016 Feb 3. Nature. 2016. PMID: 26840489 Free PMC article.
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
Baker DJ, Wijshake T, Tchkonia T, LeBrasseur NK, Childs BG, van de Sluis B, Kirkland JL, van Deursen JM. Baker DJ, et al. Among authors: Childs BG, van Deursen JM. Nature. 2011 Nov 2;479(7372):232-6. doi: 10.1038/nature10600. Nature. 2011. PMID: 22048312 Free PMC article.
Senescent cells: an emerging target for diseases of ageing.
Childs BG, Gluscevic M, Baker DJ, Laberge RM, Marquess D, Dananberg J, van Deursen JM. Childs BG, et al. Among authors: van Deursen JM. Nat Rev Drug Discov. 2017 Oct;16(10):718-735. doi: 10.1038/nrd.2017.116. Epub 2017 Jul 21. Nat Rev Drug Discov. 2017. PMID: 28729727 Free PMC article. Review.
Senescence and apoptosis: dueling or complementary cell fates?
Childs BG, Baker DJ, Kirkland JL, Campisi J, van Deursen JM. Childs BG, et al. Among authors: van Deursen JM. EMBO Rep. 2014 Nov;15(11):1139-53. doi: 10.15252/embr.201439245. Epub 2014 Oct 13. EMBO Rep. 2014. PMID: 25312810 Free PMC article. Review.
Senescent intimal foam cells are deleterious at all stages of atherosclerosis.
Childs BG, Baker DJ, Wijshake T, Conover CA, Campisi J, van Deursen JM. Childs BG, et al. Among authors: van Deursen JM. Science. 2016 Oct 28;354(6311):472-477. doi: 10.1126/science.aaf6659. Epub 2016 Oct 27. Science. 2016. PMID: 27789842 Free PMC article.
Senescent cells: a therapeutic target for cardiovascular disease.
Childs BG, Li H, van Deursen JM. Childs BG, et al. Among authors: van Deursen JM. J Clin Invest. 2018 Apr 2;128(4):1217-1228. doi: 10.1172/JCI95146. Epub 2018 Apr 2. J Clin Invest. 2018. PMID: 29608141 Free PMC article. Review.
Inhibition of 'jumping genes' promotes healthy ageing.
Childs B, van Deursen J. Childs B, et al. Among authors: van Deursen J. Nature. 2019 Feb;566(7742):46-48. doi: 10.1038/d41586-018-07553-0. Nature. 2019. PMID: 30728507 No abstract available.
Spartan deficiency causes genomic instability and progeroid phenotypes.
Maskey RS, Kim MS, Baker DJ, Childs B, Malureanu LA, Jeganathan KB, Machida Y, van Deursen JM, Machida YJ. Maskey RS, et al. Among authors: Childs B, van Deursen JM. Version 2. Nat Commun. 2014 Dec 11;5:5744. doi: 10.1038/ncomms6744. Nat Commun. 2014. PMID: 25501849 Free PMC article.
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