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CYP2D6 phenotypes are associated with adverse outcomes related to opioid medications.
St Sauver JL, Olson JE, Roger VL, Nicholson WT, Black JL 3rd, Takahashi PY, Caraballo PJ, Bell EJ, Jacobson DJ, Larson NB, Bielinski SJ. St Sauver JL, et al. Pharmgenomics Pers Med. 2017 Jul 24;10:217-227. doi: 10.2147/PGPM.S136341. eCollection 2017. Pharmgenomics Pers Med. 2017. PMID: 28769582 Free PMC article.
Therefore, we examined the association between CYP2D6 phenotype and poor pain control or other adverse symptoms related to the use of opioids in a sample of primary care patients. ...We removed patients that were prescribed a CYP2D6
Therefore, we examined the association between CYP2D6 phenotype and poor pain control or other adverse symptoms …
Sex Differences in Associations Between CYP2D6 Phenotypes and Response to Opioid Analgesics.
Lopes GS, Bielinski SJ, Moyer AM, Black Iii JL, Jacobson DJ, Jiang R, Larson NB, St Sauver JL. Lopes GS, et al. Pharmgenomics Pers Med. 2020 Mar 13;13:71-79. doi: 10.2147/PGPM.S239222. eCollection 2020. Pharmgenomics Pers Med. 2020. PMID: 32214840 Free PMC article.
BACKGROUND: Several small studies have previously investigated associations between the cytochrome P450 2D6 (CYP2D6) metabolism and response to opioids. ...Opioid-related outcomes included indications of poor pain control or adv
BACKGROUND: Several small studies have previously investigated associations between the cytochrome P450 2D6 (CYP2D6) me …
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