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Page 1
Discovery, Characterization, and Engineering of LvIC, an alpha4/4-Conotoxin That Selectively Blocks Rat alpha6/alpha3beta4 Nicotinic Acetylcholine Receptors.
Zhu X, Wang S, Kaas Q, Yu J, Wu Y, Harvey PJ, Zhangsun D, Craik DJ, Luo S. Zhu X, et al. J Med Chem. 2023 Feb 9;66(3):2020-2031. doi: 10.1021/acs.jmedchem.2c01786. Epub 2023 Jan 22. J Med Chem. 2023. PMID: 36682014
Here, we characterized a novel alpha-conotoxin, LvIC, and designed a series of analogues to probe structure-activity relationships at the alpha6beta4 nAChR. ...Using NMR, molecular docking, and receptor mutation, structure-activity relationships of [D1G,deltaQ14]LvIC …
Here, we characterized a novel alpha-conotoxin, LvIC, and designed a series of analogues to probe structure-activity relationships at …
Synthesis, Activity, and Application of Fluorescent Analogs of [D1G, delta14Q]LvIC Targeting alpha6beta4 Nicotinic Acetylcholine Receptor.
Pei S, Xu C, Tan Y, Wang M, Yu J, Zhangsun D, Zhu X, Luo S. Pei S, et al. Bioconjug Chem. 2023 Dec 20;34(12):2194-2204. doi: 10.1021/acs.bioconjchem.3c00283. Epub 2023 Sep 25. Bioconjug Chem. 2023. PMID: 37748043
As one of the analogs of alpha-conotoxin (alpha-CTx) LvIC from Conus lividus, [D1G, delta14Q]LvIC (Lv) selectively and potently blocks alpha6/alpha3beta4 nAChR (alpha6/alpha3 represents a chimera). ...Our findings not only provide a visualized pharmacological tool f …
As one of the analogs of alpha-conotoxin (alpha-CTx) LvIC from Conus lividus, [D1G, delta14Q]LvIC (Lv) selectively and potentl …
Learning Lossless Compression for High Bit-Depth Volumetric Medical Image.
Wang K, Bai Y, Li D, Zhai D, Jiang J, Liu X. Wang K, et al. IEEE Trans Image Process. 2024 Dec 12;PP. doi: 10.1109/TIP.2024.3513156. Online ahead of print. IEEE Trans Image Process. 2024. PMID: 40030527
To address these challenges, this paper presents the Bit-Division based Lossless Volumetric Image Compression (BD-LVIC) framework, which is tailored for high bit-depth medical volume compression. The BD-LVIC framework skillfully divides the high bit-depth volume int …
To address these challenges, this paper presents the Bit-Division based Lossless Volumetric Image Compression (BD-LVIC) framework, wh …
A novel alpha-conotoxin [D1G, deltaQ14] LvIC decreased mouse locomotor activity.
Wang W, Wang M, Wang H, Xu W, Wang C, Pei J, Li X, Zhangsun D. Wang W, et al. Front Pharmacol. 2025 Jan 21;15:1466504. doi: 10.3389/fphar.2024.1466504. eCollection 2024. Front Pharmacol. 2025. PMID: 39906393 Free PMC article.
However, the effects of [D1G, deltaQ14] LvIC have not been investigated in vivo. This study aims to examine the activities of [D1G, deltaQ14] LvIC and explore its potential mechanisms in vivo. ...This study first proposed that [D1G, deltaQ14] LvIC could modul …
However, the effects of [D1G, deltaQ14] LvIC have not been investigated in vivo. This study aims to examine the activities of [D1G, d …
EMG-Based Variable Impedance Control for Enhanced Haptic Feedback in Real-Time Material Recognition.
Iovene E, Monaco R, Fu J, Costa F, Ferrigno G, Momi E. Iovene E, et al. IEEE Trans Haptics. 2025 Jan-Mar;18(1):220-231. doi: 10.1109/TOH.2024.3524023. Epub 2025 Mar 21. IEEE Trans Haptics. 2025. PMID: 40030947
Technical validation and a user study assessed performance compared to constant parameter (CIC) and linear variable (LVIC) impedance control methods. Results showed reduced contact force ( vs CIC's and LVIC's ) and in-contact displacement ( vs CIC's and LVIC' …
Technical validation and a user study assessed performance compared to constant parameter (CIC) and linear variable (LVIC) impedance …
Comparative Study on Iron Content Detection by Energy Spectral CT and MRI in MDS Patients.
Zhang Y, Xiao C, Li J, Song LX, Zhao YS, Han S, Li ZW, Guo C, Zhao JG, Chang CK. Zhang Y, et al. Front Oncol. 2021 Mar 22;11:646946. doi: 10.3389/fonc.2021.646946. eCollection 2021. Front Oncol. 2021. PMID: 33828991 Free PMC article.
There was no significant difference between LVIC Az and LIC Az in the subgroup with 1,000 ASF < 2,500 ng/ml and 2,500 ASF < 5,000 ng/ml. LVIC Az was significantly higher than LIC Az in the subgroup with ASF <5,000 and 5,000 ASF ng/ml. ...

There was no significant difference between LVIC Az and LIC Az in the subgroup with 1,000 ASF < 2,500 ng/ml and 2,500 ASF <

…
Using low voltage ionization chamber (LVIC) in current mode for energy spectrum reconstruction: Experiments and validation.
Mazon D, Colette D, Soudet E, Malard P, Walsh M, Moreau M, Jardin A. Mazon D, et al. Rev Sci Instrum. 2022 Nov 1;93(11):113544. doi: 10.1063/5.0105345. Rev Sci Instrum. 2022. PMID: 36461489
Instead, robust detectors, such as gas-filled detectors, are nowadays considered. The Low Voltage Ionization Chamber (LVIC) is one of the most promising candidates for x-ray measurement during the ITER nuclear phase. ...Experimental testing at the IRFM laboratory of an ITE …
Instead, robust detectors, such as gas-filled detectors, are nowadays considered. The Low Voltage Ionization Chamber (LVIC) is one of …
Conceptual study of energy resolved x-ray measurement and electron temperature reconstruction on ITER with low voltage ionization chambers.
Colette D, Mazon D, Barnsley R, O'Mullane M, Jardin A, Sirinelli A. Colette D, et al. Rev Sci Instrum. 2021 Aug 1;92(8):083511. doi: 10.1063/5.0028460. Rev Sci Instrum. 2021. PMID: 34470374 Free article.
This article presents a conceptual study of the use of a multi-anode LVIC for energy resolved x-ray measurement on ITER. It covers the design of the multi-anode LVIC and its modeling, the method for spectral deconvolution, and its application to energy resolved x-ra …
This article presents a conceptual study of the use of a multi-anode LVIC for energy resolved x-ray measurement on ITER. It covers th …
A needleless liquid jet injection delivery method for cardiac gene therapy: a comparative evaluation versus standard routes of delivery reveals enhanced therapeutic retention and cardiac specific gene expression.
Fargnoli AS, Katz MG, Williams RD, Margulies KB, Bridges CR. Fargnoli AS, et al. J Cardiovasc Transl Res. 2014 Nov;7(8):756-67. doi: 10.1007/s12265-014-9593-1. Epub 2014 Oct 15. J Cardiovasc Transl Res. 2014. PMID: 25315468 Free PMC article.
This study evaluates needleless liquid jet method and compares it with three common experimental methods: (1) intramuscular injection (IM), (2) left ventricular intracavitary infusion (LVIC), and (3) LV intracavitary infusion with aortic and pulmonary occlusion (LVIC …
This study evaluates needleless liquid jet method and compares it with three common experimental methods: (1) intramuscular injection (IM), …
12 results