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2011 2
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2013 2
2014 1
2015 1
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2023 12
2024 16

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49 results

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Page 1
Antioxidant enzymes and Nrf2/Keap1 in human skeletal muscle: Influence of age, sex, adiposity and aerobic fitness.
Galvan-Alvarez V, Gallego-Selles A, Martinez-Canton M, García-Gonzalez E, Gelabert-Rebato M, Ponce-Gonzalez JG, Larsen S, Morales-Alamo D, Losa-Reyna J, Perez-Suarez I, Dorado C, Perez-Valera M, Holmberg HC, Boushel R, de Pablos Velasco P, Helge JW, Martin-Rincon M, Calbet JAL. Galvan-Alvarez V, et al. Free Radic Biol Med. 2023 Nov 20;209(Pt 2):282-291. doi: 10.1016/j.freeradbiomed.2023.10.393. Epub 2023 Oct 17. Free Radic Biol Med. 2023. PMID: 37858747 Free article.
Ageing, a sedentary lifestyle, and obesity are associated with increased oxidative stress, while regular exercise is associated with an increased antioxidant capacity in trained skeletal muscles. Whether a higher aerobic fitness is associated with increased expressi …
Ageing, a sedentary lifestyle, and obesity are associated with increased oxidative stress, while regular exercise is associated with an incr …
Exercise-induced Nrf2 activation increases antioxidant defenses in skeletal muscles.
Powers SK, Lategan-Potgieter R, Goldstein E. Powers SK, et al. Free Radic Biol Med. 2024 Aug 23;224:470-478. doi: 10.1016/j.freeradbiomed.2024.07.041. Online ahead of print. Free Radic Biol Med. 2024. PMID: 39181477 Review.
Following the discovery that exercise increases the production of reactive oxygen species in contracting skeletal muscles, evidence quickly emerged that endurance exercise training increases the abundance of key antioxidant enzymes in the trained muscles. ... …
Following the discovery that exercise increases the production of reactive oxygen species in contracting skeletal muscles, evi …
Effects of environmental hypoxia on the goldfish skeletal muscle: Focus on oxidative status and mitochondrial dynamics.
Filice M, Caferro A, Gattuso A, Sperone E, Agnisola C, Faggio C, Cerra MC, Imbrogno S. Filice M, et al. J Contam Hydrol. 2024 Feb;261:104299. doi: 10.1016/j.jconhyd.2024.104299. Epub 2024 Jan 12. J Contam Hydrol. 2024. PMID: 38237486 Free article.
The skeletal muscle is a highly plastic tissue. Its ability to respond to external stimuli and challenges allows it to face the functional needs of the organism. ...Our results revealed novel aspects of the molecular mechanisms that in the goldfish skeletal …
The skeletal muscle is a highly plastic tissue. Its ability to respond to external stimuli and challenges allows it to face th …
TBBPA induces inflammation, apoptosis, and necrosis of skeletal muscle in mice through the ROS/Nrf2/TNF-alpha signaling pathway.
Zhang Q, Wang S, Wang F, Guo M, Xu S. Zhang Q, et al. Environ Pollut. 2023 Jan 15;317:120745. doi: 10.1016/j.envpol.2022.120745. Epub 2022 Nov 25. Environ Pollut. 2023. PMID: 36442820
However, the mechanism of TBBPA-induced skeletal muscle injury remains unclear. In this study, we constructed mouse skeletal muscle models (10, 20, and 40 mg/kg TBBPA) and mouse myoblasts (C2C12) cell models (2,4, and 8 mug/L TBBPA) at different concen …
However, the mechanism of TBBPA-induced skeletal muscle injury remains unclear. In this study, we constructed mouse skeleta …
Nrf2 modulates contractile and metabolic properties of skeletal muscle in streptozotocin-induced diabetic atrophy.
Whitman SA, Long M, Wondrak GT, Zheng H, Zhang DD. Whitman SA, et al. Exp Cell Res. 2013 Oct 15;319(17):2673-83. doi: 10.1016/j.yexcr.2013.07.015. Epub 2013 Jul 27. Exp Cell Res. 2013. PMID: 23896025 Free PMC article.
The role of Nrf2 in disease prevention and treatment is well documented; however the specific role of Nrf2 in skeletal muscle is not well described. The current study investigated whether Nrf2 plays a protective role in an STZ-induced model of …
The role of Nrf2 in disease prevention and treatment is well documented; however the specific role of Nrf2 in skeletal …
Influence of Nrf2 activators on subcellular skeletal muscle protein and DNA synthesis rates after 6 weeks of milk protein feeding in older adults.
Konopka AR, Laurin JL, Musci RV, Wolff CA, Reid JJ, Biela LM, Zhang Q, Peelor FF 3rd, Melby CL, Hamilton KL, Miller BF. Konopka AR, et al. Geroscience. 2017 Apr;39(2):175-186. doi: 10.1007/s11357-017-9968-8. Epub 2017 Mar 10. Geroscience. 2017. PMID: 28283797 Free PMC article. Clinical Trial.
CLA decreased oxidative stress and skeletal muscle oxidative damage with a trend to increase messenger RNA (mRNA) expression of a Nrf2 target, NAD(P)H dehydrogenase quinone 1 (NQO1). ...Overall, these data suggest that Protandim may enhance proteostatic mecha …
CLA decreased oxidative stress and skeletal muscle oxidative damage with a trend to increase messenger RNA (mRNA) expression o …
Effect of Genistein Supplementation on Exercise-Induced Inflammation and Oxidative Stress in Mice Liver and Skeletal Muscle.
Wu C, Zhou S, Ma S, Suzuki K. Wu C, et al. Medicina (Kaunas). 2021 Sep 27;57(10):1028. doi: 10.3390/medicina57101028. Medicina (Kaunas). 2021. PMID: 34684067 Free PMC article.
Results: Plasma aspartate aminotransferase (AST), alanine aminotransferase (ALT) levels, liver interleukin (IL)-6, IL-1beta, superoxide dismutase 1 (SOD1), catalase (CAT), hemeoxygenase-1 (HO-1) gene expression levels and skeletal muscle IL-6, nuclear factor erythro …
Results: Plasma aspartate aminotransferase (AST), alanine aminotransferase (ALT) levels, liver interleukin (IL)-6, IL-1beta, superoxide dism …
Binge alcohol induces NRF2-related antioxidant response in the skeletal muscle of female mice.
Tice AL, Steiner JL. Tice AL, et al. Biochem Biophys Res Commun. 2024 Jun 25;714:149968. doi: 10.1016/j.bbrc.2024.149968. Epub 2024 Apr 20. Biochem Biophys Res Commun. 2024. PMID: 38657445
BACKGROUND: Chronic alcohol enhances oxidative stress, but the temporal response of antioxidant genes in skeletal muscle following a binge drinking episode remains unknown. METHODS: Experiment 1: C57BL/6Hsd female mice received an IP injection of saline (CON; n = 39 …
BACKGROUND: Chronic alcohol enhances oxidative stress, but the temporal response of antioxidant genes in skeletal muscle follo …
Mediators of Physical Activity Protection against ROS-Linked Skeletal Muscle Damage.
Di Meo S, Napolitano G, Venditti P. Di Meo S, et al. Int J Mol Sci. 2019 Jun 20;20(12):3024. doi: 10.3390/ijms20123024. Int J Mol Sci. 2019. PMID: 31226872 Free PMC article. Review.
However, it is clear that redox signaling influences numerous transcriptional activators, which regulate the expression of genes involved in changes in muscle phenotype. The mitogen-activated protein kinase family is one of the main links between cellular oxidant le …
However, it is clear that redox signaling influences numerous transcriptional activators, which regulate the expression of genes invo …
Determinants of the maximal functional reserve during repeated supramaximal exercise by humans: The roles of Nrf2/Keap1, antioxidant proteins, muscle phenotype and oxygenation.
Galvan-Alvarez V, Martin-Rincon M, Gallego-Selles A, Martínez Canton M, HamedChaman N, Gelabert-Rebato M, Perez-Valera M, García-Gonzalez E, Santana A, Holmberg HC, Boushel R, Hallén J, Calbet JAL. Galvan-Alvarez V, et al. Redox Biol. 2023 Oct;66:102859. doi: 10.1016/j.redox.2023.102859. Epub 2023 Aug 22. Redox Biol. 2023. PMID: 37666117 Free PMC article.
Exercise performance, cardiorespiratory variables, oxygen deficit, and brain and muscle oxygenation (near-infrared spectroscopy) were measured, and resting muscle biopsies were obtained from 43 young healthy adults (30 males). ...The aerobic component depends on bra …
Exercise performance, cardiorespiratory variables, oxygen deficit, and brain and muscle oxygenation (near-infrared spectroscopy) were …
49 results