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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 1
1988 3
1989 3
1990 3
1991 2
1992 1
1993 3
1994 3
1995 2
1996 3
1997 2
1999 2
2002 2
2003 6
2004 11
2005 5
2006 1
2007 4
2008 4
2009 3
2010 7
2011 4
2012 3
2013 9
2014 10
2015 10
2016 20
2017 21
2018 14
2019 13
2020 18
2021 10
2022 10
2023 10
2024 7

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207 results

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Page 1
A transposase-derived gene required for human brain development.
Zapater LJ, Rodriguez-Fos E, Planas-Felix M, Lewis S, Cameron D, Demarest P, Nabila A, Zhao J, Bergin P, Reed C, Yamada M, Pagnozzi A, Nava C, Bourel-Ponchel E, Neilson DE, Dursun A, Özgül RK, Akar HT, Socci ND, Hayes M, Rabadan R, Torrents D, Kruer MC, Toth M, Kentsis A. Zapater LJ, et al. bioRxiv [Preprint]. 2023 May 23:2023.04.28.538770. doi: 10.1101/2023.04.28.538770. bioRxiv. 2023. PMID: 37163102 Free PMC article. Preprint.
Here, we show that PGBD5 contributes to normal brain development in mice and humans, where its deficiency causes disorder of intellectual disability, movement and seizures. In mice, Pgbd5 is required for the developmental induction of post-mitotic DNA breaks and rec …
Here, we show that PGBD5 contributes to normal brain development in mice and humans, where its deficiency causes disorder of intellec …
Fat-On-A-Chip Models for Research and Discovery in Obesity and Its Metabolic Comorbidities.
McCarthy M, Brown T, Alarcon A, Williams C, Wu X, Abbott RD, Gimble J, Frazier T. McCarthy M, et al. Tissue Eng Part B Rev. 2020 Dec;26(6):586-595. doi: 10.1089/ten.TEB.2019.0261. Epub 2020 Dec 3. Tissue Eng Part B Rev. 2020. PMID: 32216545 Free PMC article. Review.
The majority of current obesity research has focused primarily on preclinical animal models in vivo and two-dimensional cell culture models in vitro. ...Consequently, there is a growing demand and need for more sophisticated microphysiological systems to repr …
The majority of current obesity research has focused primarily on preclinical animal models in vivo and two-dimensional …
Mechanism of Antitumor Effects of Saffron in Human Prostate Cancer Cells.
Khan M, Hearn K, Parry C, Rasid M, Brim H, Ashktorab H, Kwabi-Addo B. Khan M, et al. Nutrients. 2023 Dec 28;16(1):114. doi: 10.3390/nu16010114. Nutrients. 2023. PMID: 38201944 Free PMC article.
The oral administration of saffron extract has been reported to have antitumor effects on aggressive prostate-cancer-cell-line-derived xenografts in nude male mice. The objective of this study was to carry out in vitro studies of saffron-treated prostate cancer cells to as …
The oral administration of saffron extract has been reported to have antitumor effects on aggressive prostate-cancer-cell-line-derived xenog …
Factor IX(a) inhibitors: an updated patent review (2003-present).
Afosah DK, Ofori E, Mottamal M, Al-Horani RA. Afosah DK, et al. Expert Opin Ther Pat. 2022 Apr;32(4):381-400. doi: 10.1080/13543776.2022.2026926. Epub 2022 Jan 17. Expert Opin Ther Pat. 2022. PMID: 34991418 Free PMC article. Review.
Clinically used thrombin- and/or factor Xa-based anticoagulants continue to be associated with a significant bleeding risk which limits their safe use in a broad range of thrombotic patients. Research findings in animals and humans indicate that it is possible to target fa …
Clinically used thrombin- and/or factor Xa-based anticoagulants continue to be associated with a significant bleeding risk which limits thei …
New Era: Mavacamten for Obstructive Hypertrophic Cardiomyopathy.
Woodland M, Al-Horani RA. Woodland M, et al. Cardiovasc Hematol Agents Med Chem. 2023;21(2):78-83. doi: 10.2174/1871525721666221019095218. Cardiovasc Hematol Agents Med Chem. 2023. PMID: 36278454 Free PMC article. Review.
Obstructive hypertrophic cardiomyopathy is linked to mutations in genes that encode for sarcomere proteins, including actin, beta-myosin heavy chain, titin, and troponin. The mutations lead to structural abnormalities in myocytes and myofibrils, causing conduction irregula …
Obstructive hypertrophic cardiomyopathy is linked to mutations in genes that encode for sarcomere proteins, including actin, beta-myosin hea …
Current Development of Oral Taxane Formulations: A Review.
Chowdhury N, Singh M. Chowdhury N, et al. Crit Rev Ther Drug Carrier Syst. 2020;37(3):205-227. doi: 10.1615/CritRevTherDrugCarrierSyst.2020029699. Crit Rev Ther Drug Carrier Syst. 2020. PMID: 32749138 Review.
Design, synthesis, and antitumor study of a series of novel 1-Oxa-4-azaspironenone derivatives.
Yin H, Chen Y, Zhong Q, Zheng S, Wang G, He L. Yin H, et al. Bioorg Med Chem Lett. 2022 Oct 15;74:128925. doi: 10.1016/j.bmcl.2022.128925. Epub 2022 Aug 6. Bioorg Med Chem Lett. 2022. PMID: 35944852 Free PMC article.
To reduce harmful side effects, the authors started with p-aminophenol to make 1-oxo-4- azaspirodecanedione derivatives, then utilized the Michael addition and cyclopropanation to eliminate alpha, beta unsaturated olefinic bond and lower the Michael reactivity of the compounds …
To reduce harmful side effects, the authors started with p-aminophenol to make 1-oxo-4- azaspirodecanedione derivatives, then utilized the M …
207 results