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Extracellular matrix produced by bone marrow stromal cells and by their derivative, SB623 cells, supports neural cell growth.
Aizman I, Tate CC, McGrogan M, Case CC. Aizman I, et al. J Neurosci Res. 2009 Nov 1;87(14):3198-206. doi: 10.1002/jnr.22146. J Neurosci Res. 2009. PMID: 19530164
It is known that the extracellular matrix (ECM) modulates neuritogenesis and glial growth, but little is known about effects of MSC-derived ECM on neural cells. In this study, we demonstrate in vitro that the ECM produced by MSC ca …
It is known that the extracellular matrix (ECM) modulates neuritogenesis and glial growth, but little is known about ef …
Comparison of the neuropoietic activity of gene-modified versus parental mesenchymal stromal cells and the identification of soluble and extracellular matrix-related neuropoietic mediators.
Aizman I, Tirumalashetty BJ, McGrogan M, Case CC. Aizman I, et al. Stem Cell Res Ther. 2014 Feb 26;5(1):29. doi: 10.1186/scrt418. Stem Cell Res Ther. 2014. PMID: 24572070 Free PMC article.
INTRODUCTION: Transplanting mesenchymal stromal cells (MSCs) or their derivatives into a neurodegenerative environment is believed to be beneficial because of the trophic support, migratory guidance, immunosuppression, and neurogenic stimuli the …
INTRODUCTION: Transplanting mesenchymal stromal cells (MSCs) or their derivatives into a neurodegenerative envir …
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