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Radiation-Induced Lipid Peroxidation Triggers Ferroptosis and Synergizes with Ferroptosis Inducers.
Ye LF, Chaudhary KR, Zandkarimi F, Harken AD, Kinslow CJ, Upadhyayula PS, Dovas A, Higgins DM, Tan H, Zhang Y, Buonanno M, Wang TJC, Hei TK, Bruce JN, Canoll PD, Cheng SK, Stockwell BR. Ye LF, et al. Among authors: buonanno m. ACS Chem Biol. 2020 Feb 21;15(2):469-484. doi: 10.1021/acschembio.9b00939. Epub 2020 Jan 14. ACS Chem Biol. 2020. PMID: 31899616 Free PMC article.
Although radiation is widely used to treat cancers, resistance mechanisms often develop and involve activation of DNA repair and inhibition of apoptosis. Therefore, compounds that sensitize cancer cells to radiation via alternative cell death pathways are valuable. …
Although radiation is widely used to treat cancers, resistance mechanisms often develop and involve activation of DNA repair a …
Biochemical and Structural Insights into the Winged Helix Domain of P150, the Largest Subunit of the Chromatin Assembly Factor 1.
Ayoub J, Buonanno M, Di Fiore A, De Simone G, Monti SM. Ayoub J, et al. Among authors: monti sm, di fiore a, buonanno m, de simone g. Int J Mol Sci. 2022 Feb 15;23(4):2160. doi: 10.3390/ijms23042160. Int J Mol Sci. 2022. PMID: 35216276 Free PMC article.
The Chromatin Assembly Factor 1 is a heterotrimeric complex responsible for the nucleosome assembly during DNA replication and DNA repair. ...Structural and functional studies targeting P150 are still li …
The Chromatin Assembly Factor 1 is a heterotrimeric complex responsible for the nucleosome assembly …
Initial genome sequencing and analysis of multiple myeloma.
Chapman MA, Lawrence MS, Keats JJ, Cibulskis K, Sougnez C, Schinzel AC, Harview CL, Brunet JP, Ahmann GJ, Adli M, Anderson KC, Ardlie KG, Auclair D, Baker A, Bergsagel PL, Bernstein BE, Drier Y, Fonseca R, Gabriel SB, Hofmeister CC, Jagannath S, Jakubowiak AJ, Krishnan A, Levy J, Liefeld T, Lonial S, Mahan S, Mfuko B, Monti S, Perkins LM, Onofrio R, Pugh TJ, Rajkumar SV, Ramos AH, Siegel DS, Sivachenko A, Stewart AK, Trudel S, Vij R, Voet D, Winckler W, Zimmerman T, Carpten J, Trent J, Hahn WC, Garraway LA, Meyerson M, Lander ES, Getz G, Golub TR. Chapman MA, et al. Among authors: monti s. Nature. 2011 Mar 24;471(7339):467-72. doi: 10.1038/nature09837. Nature. 2011. PMID: 21430775 Free PMC article.
No evidence of chromosome damage in chronic obstructive pulmonary disease (COPD).
Casella M, Miniati M, Monti S, Minichilli F, Bianchi F, Simi S. Casella M, et al. Among authors: monti s. Mutagenesis. 2006 Mar;21(2):167-71. doi: 10.1093/mutage/gel015. Epub 2006 Mar 27. Mutagenesis. 2006. PMID: 16567348
Similarly, SCE frequency did not differ in the two groups suggesting no disturbance in DNA replication. Unlike other diseases characterized by oxidative stress, COPD does not appear to be associated with DNA damage....
Similarly, SCE frequency did not differ in the two groups suggesting no disturbance in DNA replication. Unlike other diseases …