Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2009 1
2011 1
2012 1
2017 1
2018 2
2020 1
2021 1
2022 1
2023 3
2026 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

10 results

Results by year

Filters applied: . Clear all
Page 1
In brief: Off-label amitriptyline for insomnia.
[No authors listed] [No authors listed] Med Lett Drugs Ther. 2023 Mar 20;65(1672):48. doi: 10.58347/tml.2023.1672d. Med Lett Drugs Ther. 2023. PMID: 36897604 No abstract available.
Off-label low dose amitriptyline for insomnia disorder: Patient-reported outcomes.
Bakker MH, Hugtenburg JG, Smits MG, van der Horst HE, Slottje P. Bakker MH, et al. Pharmacoepidemiol Drug Saf. 2023 Apr;32(4):435-445. doi: 10.1002/pds.5561. Epub 2022 Nov 20. Pharmacoepidemiol Drug Saf. 2023. PMID: 36309966
PURPOSE: Low dose amitriptyline is prescribed off-label to improve sleep maintenance in patients with insomnia disorder. ...The reported side effects were generally the already known side effects of amitriptyline. CONCLUSION: These patient-reported outcomes support …
PURPOSE: Low dose amitriptyline is prescribed off-label to improve sleep maintenance in patients with insomnia disorder. ...The repor …
[Off-label use of psychotropic medications in pediatric wards: a prospective study].
Winterfeld U, Le Heuzey MF, Acquaviva E, Mouren MC, Brion F, Bourdon O. Winterfeld U, et al. Arch Pediatr. 2009 Sep;16(9):1252-60. doi: 10.1016/j.arcped.2009.06.012. Epub 2009 Jul 28. Arch Pediatr. 2009. PMID: 19640689 French.
The 5 drugs most commonly prescribed off label were risperidone (12%), clobazam (12%), amitriptyline (11%), hydroxyzine (10%) and diazepam (7%). Nearly half (47%) of all off-label prescriptions were associated with 3 indications: anxiety (24%), disruptive behaviour (12%) a …
The 5 drugs most commonly prescribed off label were risperidone (12%), clobazam (12%), amitriptyline (11%), hydroxyzine (10%) and dia …
How often are antidepressants prescribed off-label among older adults in Germany? A claims data analysis.
Schäfer W, Reinders T, Riedel O, Haug U. Schäfer W, et al. Br J Clin Pharmacol. 2021 Apr;87(4):1778-1789. doi: 10.1111/bcp.14564. Epub 2020 Nov 5. Br J Clin Pharmacol. 2021. PMID: 32986874 Free article.
While the proportion of off-label prescriptions was highest for tri- and tetracyclic antidepressants with 56.2% (amitriptyline 54.6%, maximum 65.9% for trimipramine), it amounted to 41.8% for selective serotonin reuptake inhibitors (citalopram 41.6%, maximum 46.0% for esci …
While the proportion of off-label prescriptions was highest for tri- and tetracyclic antidepressants with 56.2% (amitriptyline 54.6%, …
[Drug therapy of fibromyalgia syndrome. Systematic review, meta-analysis and guideline].
Sommer C, Häuser W, Alten R, Petzke F, Späth M, Tölle T, Uçeyler N, Winkelmann A, Winter E, Bär KJ; Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften. Sommer C, et al. Schmerz. 2012 Jun;26(3):297-310. doi: 10.1007/s00482-012-1172-2. Schmerz. 2012. PMID: 22760463 German.
The guidelines were reviewed by the boards of the participating scientific medical societies. RESULTS AND CONCLUSION: Amitriptyline and-in case of comorbid depressive disorder or generalized anxiety disorder-duloxetine are recommended. ...
The guidelines were reviewed by the boards of the participating scientific medical societies. RESULTS AND CONCLUSION: Amitriptyline a …
Trends and Patterns of Antidepressant Use in French Children and Adolescents From 2009 to 2016: A Population-Based Study in the French Health Insurance Database.
Revet A, Montastruc F, Raynaud JP, Baricault B, Montastruc JL, Lapeyre-Mestre M. Revet A, et al. J Clin Psychopharmacol. 2018 Aug;38(4):327-335. doi: 10.1097/JCP.0000000000000891. J Clin Psychopharmacol. 2018. PMID: 29851707
Sertraline was the most frequently prescribed in adolescents (2009: 22.2% of all ATD prescriptions; 2016: 32.9%), whereas amitriptyline was the most prescribed in children (2009: 42.7% and 2016: 41.2%). Off-label use decreased in adolescents (from 48.4% to 34.8%) but incre …
Sertraline was the most frequently prescribed in adolescents (2009: 22.2% of all ATD prescriptions; 2016: 32.9%), whereas amitriptyline …
Clinical Use of Pregabalin in General Practice in Catalonia, Spain: A Population-Based Cross-Sectional Study.
Viñas-Bastart M, Oms-Arias M, Pedraza-Gutiérrez À, Lizano-Díez I, Modamio P, Mariño EL. Viñas-Bastart M, et al. Pain Med. 2018 Aug 1;19(8):1639-1649. doi: 10.1093/pm/pnx159. Pain Med. 2018. PMID: 29016927
A total of 71.9% of patients started treatment with pregabalin without previously using firstline drugs, such as amitriptyline or gabapentin, and 66% of active treatments had been initiated during the year before the study. ...
A total of 71.9% of patients started treatment with pregabalin without previously using firstline drugs, such as amitriptyline or gab …
Patient-reported outcomes as a source of evidence in off-label prescribing: analysis of data from PatientsLikeMe.
Frost J, Okun S, Vaughan T, Heywood J, Wicks P. Frost J, et al. J Med Internet Res. 2011 Jan 21;13(1):e6. doi: 10.2196/jmir.1643. J Med Internet Res. 2011. PMID: 21252034 Free PMC article.
Only 104 out of 1197 members (9%) reported taking amitriptyline for its approved indication, depression. Members taking amitriptyline for off-label purposes rated the drug as more effective than those who were taking it for its approved indication. While dry mouth i …
Only 104 out of 1197 members (9%) reported taking amitriptyline for its approved indication, depression. Members taking amitriptyl …
Off-label indications for antidepressants in primary care: descriptive study of prescriptions from an indication based electronic prescribing system.
Wong J, Motulsky A, Abrahamowicz M, Eguale T, Buckeridge DL, Tamblyn R. Wong J, et al. BMJ. 2017 Feb 21;356:j603. doi: 10.1136/bmj.j603. BMJ. 2017. PMID: 28228380 Free PMC article.
By class, tricyclic antidepressants had the highest prevalence of off-label indications (81.4%, 95% confidence interval, 77.3% to 85.5%), largely due to a high off-label prescribing rate for amitriptyline (93%, 89.6% to 95.7%). Trazodone use for insomnia was the most commo …
By class, tricyclic antidepressants had the highest prevalence of off-label indications (81.4%, 95% confidence interval, 77.3% to 85.5%), la …