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Patterns and predictors of off-label prescription of psychiatric drugs.
Vijay A, Becker JE, Ross JS. Vijay A, et al. PLoS One. 2018 Jul 19;13(7):e0198363. doi: 10.1371/journal.pone.0198363. eCollection 2018. PLoS One. 2018. PMID: 30024873 Free PMC article.
The most common off-label uses were for manic-depressive psychosis treated with citalopram and primary insomnia treated with trazodone. Several patient and clinician characteristics were positively associated with off-label prescribing, including seeing a psychiatrist (OR: …
The most common off-label uses were for manic-depressive psychosis treated with citalopram and primary insomnia treated with trazodon …
Pharmacotherapy in depressed children and adolescents.
Taurines R, Gerlach M, Warnke A, Thome J, Wewetzer C. Taurines R, et al. World J Biol Psychiatry. 2011 Sep;12 Suppl 1:11-5. doi: 10.3109/15622975.2011.600295. World J Biol Psychiatry. 2011. PMID: 21905988 Review.
As second-choice antidepressants the SSRIs sertraline, escitalopram and citalopram might be used. Other antidepressants - such as tricyclic antidepressants, alpha(2)-adrenoceptor antagonists, selective noradrenalin reuptake inhibitors (SNRI) - may be alternatively used, bu …
As second-choice antidepressants the SSRIs sertraline, escitalopram and citalopram might be used. Other antidepressants - such as tri …
Progresses in treating agitation: a major clinical challenge in Alzheimer's disease.
Panza F, Solfrizzi V, Seripa D, Imbimbo BP, Santamato A, Lozupone M, Prete C, Greco A, Pilotto A, Logroscino G. Panza F, et al. Expert Opin Pharmacother. 2015;16(17):2581-8. doi: 10.1517/14656566.2015.1092520. Epub 2015 Sep 21. Expert Opin Pharmacother. 2015. PMID: 26389682 Review.
We operated a comprehensive literature search for published articles evaluating pharmacological interventions for agitation in AD, with a review of recent clinical trials on mibampator, dextromethorphan/quinidine, cannabinoids, and citalopram. EXPERT OPINION: Notwithstandi …
We operated a comprehensive literature search for published articles evaluating pharmacological interventions for agitation in AD, with a re …
An update on the advancements in the treatment of agitation in Alzheimer's disease.
Porsteinsson AP, Antonsdottir IM. Porsteinsson AP, et al. Expert Opin Pharmacother. 2017 Apr;18(6):611-620. doi: 10.1080/14656566.2017.1307340. Epub 2017 Mar 28. Expert Opin Pharmacother. 2017. PMID: 28300462 Review.
A review of several clinical trials was completed: dextromethorphan/quinidine, scyllo-inositol, brexpiprazole, prazosin, cannabinoids, citalopram, escitalopram, pimavanserin, ITI-007, ORM-12741 show promise in treating agitation. ...
A review of several clinical trials was completed: dextromethorphan/quinidine, scyllo-inositol, brexpiprazole, prazosin, cannabinoids, ci …
How often are antidepressants prescribed off-label among older adults in Germany? A claims data analysis.
Schäfer W, Reinders T, Riedel O, Haug U. Schäfer W, et al. Br J Clin Pharmacol. 2021 Apr;87(4):1778-1789. doi: 10.1111/bcp.14564. Epub 2020 Nov 5. Br J Clin Pharmacol. 2021. PMID: 32986874 Free article.
While the proportion of off-label prescriptions was highest for tri- and tetracyclic antidepressants with 56.2% (amitriptyline 54.6%, maximum 65.9% for trimipramine), it amounted to 41.8% for selective serotonin reuptake inhibitors (citalopram 41.6%, maximum 46.0% for esci …
While the proportion of off-label prescriptions was highest for tri- and tetracyclic antidepressants with 56.2% (amitriptyline 54.6%, maximu …
Treatment patterns of agitation associated with Alzheimer's dementia (AAD) patients in Canada.
Littmann-Crites V, Marrache AM, Tan C, Nightingale N, Neish CS, Therrien F, Ismail Z. Littmann-Crites V, et al. Int Psychogeriatr. 2026 Sep;38(5):100209. doi: 10.1016/j.inpsyc.2026.100209. Epub 2026 Apr 18. Int Psychogeriatr. 2026. PMID: 42000213 Free article.
Patients received between 500 and 2000 unique combinations across therapy lines. Citalopram, escitalopram, gabapentin, lorazepam, mirtazapine, pregabalin, quetiapine, risperidone, sertraline, and trazodone ranked in the top 10 therapies. ...
Patients received between 500 and 2000 unique combinations across therapy lines. Citalopram, escitalopram, gabapentin, lorazepam, mir …
Donepezil Treatment in Patients With Depression and Cognitive Impairment on Stable Antidepressant Treatment: A Randomized Controlled Trial.
Devanand DP, Pelton GH, D'Antonio K, Ciarleglio A, Scodes J, Andrews H, Lunsford J, Beyer JL, Petrella JR, Sneed J, Ciovacco M, Doraiswamy PM. Devanand DP, et al. Am J Geriatr Psychiatry. 2018 Oct;26(10):1050-1060. doi: 10.1016/j.jagp.2018.05.008. Epub 2018 Jun 28. Am J Geriatr Psychiatry. 2018. PMID: 30037778 Free PMC article. Clinical Trial.
Patients received open-label antidepressant treatment for 16 weeks, initially with citalopram and then with venlafaxine, if needed, followed by random assignment to add-on donepezil 5-10 mg daily or placebo for another 62 weeks. ...
Patients received open-label antidepressant treatment for 16 weeks, initially with citalopram and then with venlafaxine, if needed, f …
[Depressive disorders in childhood and adolescence - an analysis of KinderAGATE 2010].
Stegmann B, Wenzel-Seifert K, Haen E. Stegmann B, et al. Z Kinder Jugendpsychiatr Psychother. 2013 Mar;41(2):109-19. doi: 10.1024/1422-4917/a000218. Z Kinder Jugendpsychiatr Psychother. 2013. PMID: 23425613 German.
Fluoxetine and mirtazapine were the most frequently prescribed substances. Sertraline, escitalopram, and citalopram were also prescribed. CONCLUSION: A reserved medical treatment can be observed in child and adolescence psychiatry. ...
Fluoxetine and mirtazapine were the most frequently prescribed substances. Sertraline, escitalopram, and citalopram were also prescri …