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Off-label use of second-generation antipsychotics in borderline personality disorder: a comparative real-world study among oral and long-acting injectables in Spain.
García-Carmona JA, Simal-Aguado J, Campos-Navarro MP, Valdivia-Muñoz F, Galindo-Tovar A. García-Carmona JA, et al. Int Clin Psychopharmacol. 2021 Jul 1;36(4):201-207. doi: 10.1097/YIC.0000000000000357. Int Clin Psychopharmacol. 2021. PMID: 33853106
Moreover, PP1M and PP3M used lower daily dose of diazepam equivalents compared with the aripiprazole-1-month and RLAI treatment groups. In conclusion, the use of LAIs may play a role in the management of BPD....
Moreover, PP1M and PP3M used lower daily dose of diazepam equivalents compared with the aripiprazole-1-month and RLAI treatment group …
Pharmacologic management of non-neurogenic functional obstruction in women.
Cohn JA, Brown ET, Reynolds WS, Kaufman MR, Dmochowski RR. Cohn JA, et al. Expert Opin Drug Metab Toxicol. 2016 Jun;12(6):657-67. doi: 10.1080/17425255.2016.1178239. Epub 2016 Apr 28. Expert Opin Drug Metab Toxicol. 2016. PMID: 27095013 Review.
Specific medications reviewed include vaginal diazepam, baclofen, urethral botulinum toxin injection, and alpha-adrenergic blockers. EXPERT OPINION: Alpha-blockers in particular have demonstrated promise in women with demonstrable or suspected bladder outlet obstruction wi …
Specific medications reviewed include vaginal diazepam, baclofen, urethral botulinum toxin injection, and alpha-adrenergic blockers. …
Off-Label and Unlicensed Drugs in Pediatric Palliative Care: A Prospective Observational Study.
García-López I, Cuervas-Mons Vendrell M, Martín Romero I, de Noriega I, Benedí González J, Martino-Alba R. García-López I, et al. J Pain Symptom Manage. 2020 Nov;60(5):923-932. doi: 10.1016/j.jpainsymman.2020.06.014. Epub 2020 Jun 20. J Pain Symptom Manage. 2020. PMID: 32569831 Free article.
The main drugs used off label were oral morphine, oral levetiracetam, inhaled albuterol, sublingual ondansetron, oral tizanidine, sublingual fentanyl, and oral diazepam. The main symptoms treated with off-label drugs were dyspnea, pain, and nausea/vomiting. ...
The main drugs used off label were oral morphine, oral levetiracetam, inhaled albuterol, sublingual ondansetron, oral tizanidine, sublingual …
A Systematic Review of Intravaginal Diazepam for the Treatment of Pelvic Floor Hypertonic Disorder.
Stone RH, Abousaud M, Abousaud A, Kobak W. Stone RH, et al. J Clin Pharmacol. 2020 Dec;60 Suppl 2:S110-S120. doi: 10.1002/jcph.1775. J Clin Pharmacol. 2020. PMID: 33274514
This systematic review evaluates the efficacy of intravaginal diazepam in treating chronic pelvic pain and sexual dysfunction associated with high-tone pelvic floor dysfunction. ...Intravaginal diazepam may be helpful in women with a specific diagnosis of high-tone …
This systematic review evaluates the efficacy of intravaginal diazepam in treating chronic pelvic pain and sexual dysfunction associa …
[Off-label use of psychotropic medications in pediatric wards: a prospective study].
Winterfeld U, Le Heuzey MF, Acquaviva E, Mouren MC, Brion F, Bourdon O. Winterfeld U, et al. Arch Pediatr. 2009 Sep;16(9):1252-60. doi: 10.1016/j.arcped.2009.06.012. Epub 2009 Jul 28. Arch Pediatr. 2009. PMID: 19640689 French.
The 5 drugs most commonly prescribed off label were risperidone (12%), clobazam (12%), amitriptyline (11%), hydroxyzine (10%) and diazepam (7%). Nearly half (47%) of all off-label prescriptions were associated with 3 indications: anxiety (24%), disruptive behaviour (12%) a …
The 5 drugs most commonly prescribed off label were risperidone (12%), clobazam (12%), amitriptyline (11%), hydroxyzine (10%) and diazepa …
Off-label prescribing during pregnancy in the UK: an analysis of 18,000 prescriptions in Liverpool Women's Hospital.
Herring C, McManus A, Weeks A. Herring C, et al. Int J Pharm Pract. 2010 Aug;18(4):226-9. doi: 10.1211/ijpp.18.04.0007. Int J Pharm Pract. 2010. PMID: 20636674
This consisted of 38 drugs (16% of total) and 1735 (10%) of the total prescriptions (e.g. lisinopril, diazepam and morphine). CONCLUSIONS: A significant number of prescriptions being used in an off-label manner at LWH are high risk. ...
This consisted of 38 drugs (16% of total) and 1735 (10%) of the total prescriptions (e.g. lisinopril, diazepam and morphine). CONCLUS …
Prescription Medications for the Treatment of Insomnia and Risk of Suicide Attempt: a Comparative Safety Study.
Lavigne JE, Hur K, Kane C, Au A, Bishop TM, Pigeon WR. Lavigne JE, et al. J Gen Intern Med. 2019 Aug;34(8):1554-1563. doi: 10.1007/s11606-019-05030-6. Epub 2019 Jun 3. J Gen Intern Med. 2019. PMID: 31161572 Free PMC article.

Agents accounting for at least 1% of total insomnia fill volume were < 200 mg trazodone, hydroxyzine, diphenhydramine, zolpidem, lorazepam, diazepam, and temazepam. Exposure was defined as an incident monotherapy exposure preceded by 12 months without any insomnia medic

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Agents accounting for at least 1% of total insomnia fill volume were < 200 mg trazodone, hydroxyzine, diphenhydramine, zolpidem, lorazepa

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