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Year Number of Results
2009 1
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Page 1
Efficacy and safety of established and off-label ADHD drug therapies for cognitive impairment or attention-deficit hyperactivity disorder symptoms in bipolar disorder: A systematic review by the ISBD Targeting Cognition Task Force.
Miskowiak KW, Obel ZK, Guglielmo R, Bonnin CDM, Bowie CR, Balanzá-Martínez V, Burdick KE, Carvalho AF, Dols A, Douglas K, Gallagher P, Kessing LV, Lafer B, Lewandowski KE, López-Jaramillo C, Martinez-Aran A, McIntyre RS, Porter RJ, Purdon SE, Schaffer A, Stokes PRA, Sumiyoshi T, Torres IJ, Van Rheenen TE, Yatham LN, Young AH, Vieta E, Hasler G. Miskowiak KW, et al. Bipolar Disord. 2024 May;26(3):216-239. doi: 10.1111/bdi.13414. Epub 2024 Mar 3. Bipolar Disord. 2024. PMID: 38433530
Three studies found treatment-related ADHD symptom reduction: two involved methylphenidate and one amphetamine salts. One study found a trend towards pro-cognitive effects of modafinil on some cognitive domains. ...Five studies had low risk of bias, eleven a moderate risk, …
Three studies found treatment-related ADHD symptom reduction: two involved methylphenidate and one amphetamine salts. One study found …
Off-label use of psychotropic drugs in youth.
Rosland HG, Wergeland GJ, Holst L. Rosland HG, et al. BMC Psychiatry. 2025 Jul 30;25(1):739. doi: 10.1186/s12888-025-07176-6. BMC Psychiatry. 2025. PMID: 40739649 Free PMC article.
The medicines that were most commonly prescribed were methylphenidate for hyperkinetic disorder, quetiapine for schizophrenia and bipolar disorder, sertraline for depressive disorder and anxiety/obsessive-compulsive disorder. ...
The medicines that were most commonly prescribed were methylphenidate for hyperkinetic disorder, quetiapine for schizophrenia and bip …
The implications of methylphenidate use by healthy medical students and doctors in South Africa.
Beyer C, Staunton C, Moodley K. Beyer C, et al. BMC Med Ethics. 2014 Mar 4;15:20. doi: 10.1186/1472-6939-15-20. BMC Med Ethics. 2014. PMID: 24592964 Free PMC article. Review.
We query whether there are cognitive benefits to the use of Methylphenidate in healthy students and doctors and whether these benefits would outweigh the risks in taking the medication. Could these benefits lead to tangible outcomes for society and could the off label-use …
We query whether there are cognitive benefits to the use of Methylphenidate in healthy students and doctors and whether these benefit …
Methylphenidate in Adults with Attention Deficit Hyperactivity Disorder and Substance Use Disorders.
Simon N, Rolland B, Karila L. Simon N, et al. Curr Pharm Des. 2015;21(23):3359-66. doi: 10.2174/1381612821666150619093254. Curr Pharm Des. 2015. PMID: 26088112 Review.
Conversely, the prevalence of ADHD among patients with SUD is 10.8%, versus 3.8% for patients without SUD. Methylphenidate (MPH) alleviates ADHD symptoms and, as such, is currently considered as a first choice medication. ...
Conversely, the prevalence of ADHD among patients with SUD is 10.8%, versus 3.8% for patients without SUD. Methylphenidate (MPH) alle …
[Supervised off-label prescribing of methylphenidate in adult ADHD].
Carton L, Dondaine T, Deheul S, Marquié C, Brigadeau F, Amad A, Devos D, Danel T, Bordet R, Cottencin O, Gautier S, Ménard O. Carton L, et al. Encephale. 2019 Feb;45(1):74-81. doi: 10.1016/j.encep.2018.05.008. Epub 2018 Aug 16. Encephale. 2019. PMID: 30122296 French.
Methylphenidate is a central nervous system stimulant that is structurally close to amphetamine and acts as a norepinephrine and dopamine reuptake inhibitor. ...One strategy among three possibilities can be decided: (1) contraindication to treatment with methylphenidate …
Methylphenidate is a central nervous system stimulant that is structurally close to amphetamine and acts as a norepinephrine and dopa …
The Safety of Drug Therapy in Children.
Wimmer S, Neubert A, Rascher W. Wimmer S, et al. Dtsch Arztebl Int. 2015 Nov 13;112(46):781-7. doi: 10.3238/arztebl.2015.0781. Dtsch Arztebl Int. 2015. PMID: 26806565 Free PMC article. Review.
RESULTS: According to reports submitted to the Drug Commission of the German Medical Association (Arzneimittelkommission der deutschen Arzteschaft, AkdA), serious ADRs can arise, for example, after the administration of dimenhydrinate, alpha-adrenergic nose drops, enemas containi …
RESULTS: According to reports submitted to the Drug Commission of the German Medical Association (Arzneimittelkommission der deutschen Arzte …
Prevalence of and factors associated with the use of methylphenidate for cognitive enhancement among university students.
Cândido RCF, Perini E, Pádua CM, Junqueira DR. Cândido RCF, et al. Einstein (Sao Paulo). 2019 Oct 24;18:eAO4745. doi: 10.31744/einstein_journal/2020AO4745. eCollection 2019. Einstein (Sao Paulo). 2019. PMID: 31664322 Free PMC article.
OBJECTIVE: To estimate the prevalence of and factors associated with the use of methylphenidate for cognitive enhancement among undergraduate students. METHODS: Simple random sample of students of the Universidade Federal de Minas Gerais (n=438), invited to answer an onlin …
OBJECTIVE: To estimate the prevalence of and factors associated with the use of methylphenidate for cognitive enhancement among under …
Recent Trends in Stimulant Usage.
Safer DJ. Safer DJ. J Atten Disord. 2016 Jun;20(6):471-7. doi: 10.1177/1087054715605915. Epub 2015 Oct 20. J Atten Disord. 2016. PMID: 26486603 Review.
METHOD: Usage patterns of stimulant medication, specifically amphetamine and methylphenidate, were analyzed for trends. The data were obtained from datasets including pharmacy claims, aggregate production quotas, bulk distribution to counties, pharmacy prescription sales, …
METHOD: Usage patterns of stimulant medication, specifically amphetamine and methylphenidate, were analyzed for trends. The data were …
Efficacy of off-label augmentation in unipolar depression: A systematic review of the evidence.
Kleeblatt J, Betzler F, Kilarski LL, Bschor T, Köhler S. Kleeblatt J, et al. Eur Neuropsychopharmacol. 2017 May;27(5):423-441. doi: 10.1016/j.euroneuro.2017.03.003. Epub 2017 Mar 17. Eur Neuropsychopharmacol. 2017. PMID: 28318897
For the six drugs dexamethasone, mecamylamine, riluzole, amantadine, pramipexole and yohimbine clear proof of efficacy was not possible due to low levels of evidence, small sample sizes or discordant results. For the two agents methylphenidate and memantine only studies wi …
For the six drugs dexamethasone, mecamylamine, riluzole, amantadine, pramipexole and yohimbine clear proof of efficacy was not possible due …
The Case of Pharmacological Neuroenhancement: Medical, Judicial and Ethical Aspects from a German Perspective.
Franke AG, Northoff R, Hildt E. Franke AG, et al. Pharmacopsychiatry. 2015 Nov;48(7):256-64. doi: 10.1055/s-0035-1559640. Epub 2015 Aug 7. Pharmacopsychiatry. 2015. PMID: 26252723 Review.
Drugs used for this purpose can be divided into freely available, over-the-counter drugs (e. g., methylxanthines such as caffeine), prescription drugs (e. g., antidementia drugs, methylphenidate) and illicit drugs (e. g., illicit amphetamines). Clinical studies have shown …
Drugs used for this purpose can be divided into freely available, over-the-counter drugs (e. g., methylxanthines such as caffeine), prescrip …
25 results