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Off-label use of antidepressants, antipsychotics, and mood-stabilizers in psychiatry.
Hefner G, Wolff J, Toto S, Reißner P, Klimke A. Hefner G, et al. J Neural Transm (Vienna). 2022 Nov;129(11):1353-1365. doi: 10.1007/s00702-022-02542-0. Epub 2022 Sep 7. J Neural Transm (Vienna). 2022. PMID: 36070009
The most often off-label prescribed drugs were quetiapine and mirtazapine for organic mental disorders (F0/G3), valproate and quetiapine in patients with disorders due to psychoactive substance use (F1), valproate in patients with psychotic disorders (F2), and risperidone …
The most often off-label prescribed drugs were quetiapine and mirtazapine for organic mental disorders (F0/G3), valproate and quetiapine in …
Off-Label Prescribing of Antipsychotics in Adults, Children and Elderly Individuals: A Systematic Review of Recent Prescription Trends.
Carton L, Cottencin O, Lapeyre-Mestre M, Geoffroy PA, Favre J, Simon N, Bordet R, Rolland B. Carton L, et al. Curr Pharm Des. 2015;21(23):3280-97. doi: 10.2174/1381612821666150619092903. Curr Pharm Des. 2015. PMID: 26088115
Among children, OLP was estimated between 36 and 93.2% of all antipsychotic prescriptions. Risperidone and aripiprazole were primarily used and were most often prescribed for attention deficit hyperactivity disorder, anxiety, or mood disorders. ...
Among children, OLP was estimated between 36 and 93.2% of all antipsychotic prescriptions. Risperidone and aripiprazole were primaril …
Long-Term Effectiveness of Off-Label Risperidone Treatment in Children and Adolescents: A Randomized, Placebo-Controlled Discontinuation Study.
Dinnissen M, Dietrich A, Bierens M, van der Molen JH, Verhallen AM, Overbeek WA, van den Hoofdakker BJ, Roke Y, Troost PW, Buitelaar JK, Hoekstra PJ. Dinnissen M, et al. J Child Adolesc Psychopharmacol. 2024 Aug;34(6):253-263. doi: 10.1089/cap.2023.0065. Epub 2024 Apr 26. J Child Adolesc Psychopharmacol. 2024. PMID: 38669110 Clinical Trial.
Objectives: Risperidone is commonly prescribed off-label in children and adolescents to manage disruptive behavior. ...Discontinuation was associated with important health gains. Despite long-term benefits of risperidone, attempts to withdraw risperidone shou …
Objectives: Risperidone is commonly prescribed off-label in children and adolescents to manage disruptive behavior. ...Discontinuatio …
Off-label use of second-generation antipsychotics in borderline personality disorder: a comparative real-world study among oral and long-acting injectables in Spain.
García-Carmona JA, Simal-Aguado J, Campos-Navarro MP, Valdivia-Muñoz F, Galindo-Tovar A. García-Carmona JA, et al. Int Clin Psychopharmacol. 2021 Jul 1;36(4):201-207. doi: 10.1097/YIC.0000000000000357. Int Clin Psychopharmacol. 2021. PMID: 33853106
The aim of the present study was to evaluate the use of oral vs. long-acting injectables (LAIs) antipsychotics, as well as, to compare the effectiveness of different LAI antipsychotics [aripiprazole-1-month, paliperidone-1-month (PP1M), paliperidone-3-month (PP3M) and risperid …
The aim of the present study was to evaluate the use of oral vs. long-acting injectables (LAIs) antipsychotics, as well as, to compare the e …
Off-label use of antipsychotic medications in psychiatric inpatients in China: a national real-world survey.
Wang J, Jiang F, Yang Y, Zhang Y, Liu Z, Qin X, Tao X, Liu T, Liu Y, Tang YL, Liu H, Cotes RO. Wang J, et al. BMC Psychiatry. 2021 Jul 27;21(1):375. doi: 10.1186/s12888-021-03374-0. BMC Psychiatry. 2021. PMID: 34315410 Free PMC article.
The top three most commonly used antipsychotics were olanzapine (29.1%), quetiapine (20.3%) and risperidone (6.8%), and their corresponding average doses were 9.04 5.80 mg/day, 185.13 174.72 mg/day, and 2.98 1.71 mg/day, respectively. ...
The top three most commonly used antipsychotics were olanzapine (29.1%), quetiapine (20.3%) and risperidone (6.8%), and their corresp …
Prescribed medicine use and extent of off-label use according to age in a nationwide sample of Australian children.
Schaffer AL, Bruno C, Buckley NA, Cairns R, Litchfield M, Paget S, Zoega H, Nassar N, Pearson SA. Schaffer AL, et al. Paediatr Perinat Epidemiol. 2022 Sep;36(5):726-737. doi: 10.1111/ppe.12870. Epub 2022 Feb 16. Paediatr Perinat Epidemiol. 2022. PMID: 35172017 Free PMC article.
Among children <1 year, off-label dispensings were commonly acid-suppressing medicines (35.5%) and topical hydrocortisone (33.1%); in children 6-11 years, off-label prescribing of clonidine (16.0%) and risperidone (13.1%) was common. Off-label dispensings were more like …
Among children <1 year, off-label dispensings were commonly acid-suppressing medicines (35.5%) and topical hydrocortisone (33.1%); in chi …
Paliperidone Use in Child Psychiatry: Evidence or Diffidence?
Naguy A, Adel T, Almazeedi I. Naguy A, et al. Pharmacology. 2019;104(1-2):67-70. doi: 10.1159/000500629. Epub 2019 May 16. Pharmacology. 2019. PMID: 31096228 Review.
However, the pharmacologic portfolio, extrapolation from adult studies, and the long track record of the parent drug, risperidone in child/adolescent psychiatric (CAP) population might expand its therapeutic potential. ...Until then, risperidone with its long track …
However, the pharmacologic portfolio, extrapolation from adult studies, and the long track record of the parent drug, risperidone in …
Summary of the comparative effectiveness review on off-label use of atypical antipsychotics.
Maher AR, Theodore G. Maher AR, et al. J Manag Care Pharm. 2012 Jun;18(5 Suppl B):S1-20. doi: 10.18553/jmcp.2012.18.s5-b.1. J Manag Care Pharm. 2012. PMID: 22784311 Free PMC article.
The significant findings in the updated review include (a) small but statistically significant benefits for olanzapine, aripiprazole, and risperidone for elderly patients with dementia; (b) quetiapine appears superior to placebo for general anxiety disorder (GAD); (c) r …
The significant findings in the updated review include (a) small but statistically significant benefits for olanzapine, aripiprazole, and …
Metabolic adverse effects of off-label use of second-generation antipsychotics in the adult population: a systematic review and meta-analysis.
Stogios N, Smith E, Bowden S, Tran V, Asgariroozbehani R, McIntyre WB, Remington G, Siskind D, Agarwal SM, Hahn MK. Stogios N, et al. Neuropsychopharmacology. 2022 Feb;47(3):664-672. doi: 10.1038/s41386-021-01163-7. Epub 2021 Aug 26. Neuropsychopharmacology. 2022. PMID: 34446830 Free PMC article.
Thirty-eight RCTs met inclusion criteria for this review; 35 of these studies, with a total of 4930 patients, were included in the quantitative meta-analysis. Patients treated with olanzapine, risperidone, and quetiapine were more likely to report weight gain as a side eff …
Thirty-eight RCTs met inclusion criteria for this review; 35 of these studies, with a total of 4930 patients, were included in the quantitat …
45 results