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Year Number of Results
2012 1
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2026 2

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Page 1
Insomnia in Elderly Patients: Recommendations for Pharmacological Management.
Abad VC, Guilleminault C. Abad VC, et al. Drugs Aging. 2018 Sep;35(9):791-817. doi: 10.1007/s40266-018-0569-8. Drugs Aging. 2018. PMID: 30058034 Review.
Benzodiazepines should not be used routinely. Trazodone, a commonly used off-label drug for insomnia, improves sleep quality and sleep continuity but carries significant risks. ...
Benzodiazepines should not be used routinely. Trazodone, a commonly used off-label drug for insomnia, improves sleep quality and slee …
Off-Label Trazodone Prescription: Evidence, Benefits and Risks.
Bossini L, Coluccia A, Casolaro I, Benbow J, Amodeo G, De Giorgi R, Fagiolini A. Bossini L, et al. Curr Pharm Des. 2015;21(23):3343-51. doi: 10.2174/1381612821666150619092236. Curr Pharm Des. 2015. PMID: 26088119 Review.
Other, not officially approved, uses of trazodone include: the treatment of bulimia, benzodiazepine and/or alcohol dependence or abuse, fibromyalgia, degenerative diseases of the central nervous system such as dementia and other organic disorders, schizophrenia, chronic pa …
Other, not officially approved, uses of trazodone include: the treatment of bulimia, benzodiazepine and/or alcohol dependence or abus …
Off-label uses of trazodone: a review.
Bossini L, Casolaro I, Koukouna D, Cecchini F, Fagiolini A. Bossini L, et al. Expert Opin Pharmacother. 2012 Aug;13(12):1707-17. doi: 10.1517/14656566.2012.699523. Epub 2012 Jun 20. Expert Opin Pharmacother. 2012. PMID: 22712761 Review.
INTRODUCTION: Trazodone is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors. ...AREAS COVERED: This paper evaluates trazodone's efficacy and safety in its off-label uses. It also discusses the possibility that a comb …
INTRODUCTION: Trazodone is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors. ...ARE …
Patterns and predictors of off-label prescription of psychiatric drugs.
Vijay A, Becker JE, Ross JS. Vijay A, et al. PLoS One. 2018 Jul 19;13(7):e0198363. doi: 10.1371/journal.pone.0198363. eCollection 2018. PLoS One. 2018. PMID: 30024873 Free PMC article.
The most common off-label uses were for manic-depressive psychosis treated with citalopram and primary insomnia treated with trazodone. Several patient and clinician characteristics were positively associated with off-label prescribing, including seeing a psychiatrist (OR: …
The most common off-label uses were for manic-depressive psychosis treated with citalopram and primary insomnia treated with trazodone …
In brief: Off-label amitriptyline for insomnia.
[No authors listed] [No authors listed] Med Lett Drugs Ther. 2023 Mar 20;65(1672):48. doi: 10.58347/tml.2023.1672d. Med Lett Drugs Ther. 2023. PMID: 36897604 No abstract available.
Treatment patterns of agitation associated with Alzheimer's dementia (AAD) patients in Canada.
Littmann-Crites V, Marrache AM, Tan C, Nightingale N, Neish CS, Therrien F, Ismail Z. Littmann-Crites V, et al. Int Psychogeriatr. 2026 Sep;38(5):100209. doi: 10.1016/j.inpsyc.2026.100209. Epub 2026 Apr 18. Int Psychogeriatr. 2026. PMID: 42000213 Free article.
Citalopram, escitalopram, gabapentin, lorazepam, mirtazapine, pregabalin, quetiapine, risperidone, sertraline, and trazodone ranked in the top 10 therapies. Risperidone accounted for 7.2% of claims and ranked as the 6th most common 1 L therapy. Although trazodone re …
Citalopram, escitalopram, gabapentin, lorazepam, mirtazapine, pregabalin, quetiapine, risperidone, sertraline, and trazodone ranked i …
[Trazodone beyond approved indications: consumption trends in Brazilian states and the Federal District, 2014-2021].
Schmidt MG, Costa JSDD, Olinto MTA, Paniz VMV. Schmidt MG, et al. Cien Saude Colet. 2026 Oct 9;31(9):e05722024. doi: 10.1590/1413-81232026319.05722024. eCollection 2026. Cien Saude Colet. 2026. PMID: 42879617 Portuguese.
Ecological study aimed to determine the consumption of low-dose trazodone (unlicensed/off label) in the Brazilian macro-regions, states, and the Federal District, to monitor the trend between the years 2014 and 2021, and to evaluate the relationship with health indicators. …
Ecological study aimed to determine the consumption of low-dose trazodone (unlicensed/off label) in the Brazilian macro-regions, stat …
A nationwide population study of trazodone use in urology patients.
Cheng WM, Lin TP, Lin AT, Chen KK, Chen TJ. Cheng WM, et al. J Chin Med Assoc. 2013 Aug;76(8):432-7. doi: 10.1016/j.jcma.2013.05.002. Epub 2013 Jun 17. J Chin Med Assoc. 2013. PMID: 23786837 Free article.
Some evidence has suggested that trazodone may be helpful in improving ED, especially for problems dealing with male arousal. Although controversial, trazodone can sometimes be used for ED as an off-label medication for urological patients. ...
Some evidence has suggested that trazodone may be helpful in improving ED, especially for problems dealing with male arousal. Althoug …
Changing Pattern of Sedative Use in Older Adults: A Population-Based Cohort Study.
Iaboni A, Bronskill SE, Reynolds KB, Wang X, Rochon PA, Herrmann N, J Flint A. Iaboni A, et al. Drugs Aging. 2016 Jul;33(7):523-33. doi: 10.1007/s40266-016-0380-3. Drugs Aging. 2016. PMID: 27241038
OBJECTIVE: Our objective was to describe the shifting patterns of sedative prescription in older adults over time by comparing changes in benzodiazepine, trazodone, and quetiapine dispensing between community and long-term care settings. METHODS: We conducted a population- …
OBJECTIVE: Our objective was to describe the shifting patterns of sedative prescription in older adults over time by comparing changes in be …
Prescription Medications for the Treatment of Insomnia and Risk of Suicide Attempt: a Comparative Safety Study.
Lavigne JE, Hur K, Kane C, Au A, Bishop TM, Pigeon WR. Lavigne JE, et al. J Gen Intern Med. 2019 Aug;34(8):1554-1563. doi: 10.1007/s11606-019-05030-6. Epub 2019 Jun 3. J Gen Intern Med. 2019. PMID: 31161572 Free PMC article.
IMPORTANCE: Guidelines for the pharmacological treatment of chronic insomnia in adults recognize that trazodone and other off-label medications are commonly prescribed despite poor evidence. ...These findings provide the first comparative effectiveness evidence against the …
IMPORTANCE: Guidelines for the pharmacological treatment of chronic insomnia in adults recognize that trazodone and other off-label m …
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