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159 results

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Page 1
Constitutive activation of two-component systems reveals regulatory network interactions in Streptococcus agalactiae.
Claverie C, Coppolino F, Mazzuoli MV, Guyonnet C, Jacquemet E, Legendre R, Sismeiro O, De Gaetano GV, Teti G, Trieu-Cuot P, Tazi A, Beninati C, Firon A. Claverie C, et al. Among authors: tazi a. Nat Commun. 2024 Oct 24;15(1):9175. doi: 10.1038/s41467-024-53439-3. Nat Commun. 2024. PMID: 39448655 Free PMC article.
Transcriptome analyses of 14 HK mutants in Streptococcus agalactiae, the leading cause of neonatal meningitis, validate the conserved HK phosphatase mechanism and its role in the inhibition of TCS activity in vivo. ...
Transcriptome analyses of 14 HK mutants in Streptococcus agalactiae, the leading cause of neonatal meningitis, validate the conserved …
The double-edged role of FASII regulator FabT in Streptococcus pyogenes infection.
Lambert C, Gaillard M, Wongdontree P, Bachmann C, Hautcoeur A, Gloux K, Guilbert T, Méhats C, Prost B, Solgadi A, Abreu S, Andrieu M, Poyart C, Gruss A, Fouet A. Lambert C, et al. Among authors: poyart c. Nat Commun. 2024 Oct 4;15(1):8593. doi: 10.1038/s41467-024-52637-3. Nat Commun. 2024. PMID: 39366941 Free PMC article.
In Streptococcus pyogenes, the type II fatty acid (FA) synthesis pathway FASII is feedback-controlled by the FabT repressor bound to an acyl-Acyl carrier protein. ...
In Streptococcus pyogenes, the type II fatty acid (FA) synthesis pathway FASII is feedback-controlled by the FabT repressor bound to …
The hypervirulent Group B Streptococcus HvgA adhesin promotes central nervous system invasion through transcellular crossing of the choroid plexus.
Aznar E, Strazielle N, Costa L, Poyart C, Tazi A, Ghersi-Egea JF, Guignot J. Aznar E, et al. Among authors: poyart c, tazi a. Fluids Barriers CNS. 2024 Aug 16;21(1):66. doi: 10.1186/s12987-024-00564-2. Fluids Barriers CNS. 2024. PMID: 39152442 Free PMC article.
BACKGROUND: Group B Streptococcus (GBS) is the leading cause of neonatal meningitis responsible for a substantial cause of death and disability worldwide. The vast majority of GBS neonatal meningitis cases are due to the CC17 hypervirulent clone. However, the …
BACKGROUND: Group B Streptococcus (GBS) is the leading cause of neonatal meningitis responsible for a substantial cause of dea …
Coordinated regulation of osmotic imbalance by c-di-AMP shapes ss-lactam tolerance in Group B Streptococcus.
Brissac T, Guyonnet C, Sadouni A, Hernández-Montoya A, Jacquemet E, Legendre R, Sismeiro O, Trieu-Cuot P, Lanotte P, Tazi A, Firon A. Brissac T, et al. Among authors: tazi a. Microlife. 2024 Jun 12;5:uqae014. doi: 10.1093/femsml/uqae014. eCollection 2024. Microlife. 2024. PMID: 38993744 Free PMC article.
Streptococcus agalactiae is among the few pathogens that have not developed resistance to ss-lactam antibiotics despite decades of clinical use. ...Genome-wide transposon mutagenesis confirms the role of GdpP and highlights functional interactions between a lysozyme-like h
Streptococcus agalactiae is among the few pathogens that have not developed resistance to ss-lactam antibiotics despite decades of cl
Recurrent Group B Streptococcus neonatal invasive infections, France, 2007 -2021.
Sbaa G, Delettre N, Guyonnet C, Nghia SLH, Joubrel-Guyot C, Plainvert C, Poyart C, Tazi A. Sbaa G, et al. Among authors: poyart c, plainvert c, tazi a. J Infect Dis. 2024 Jun 6:jiae307. doi: 10.1093/infdis/jiae307. Online ahead of print. J Infect Dis. 2024. PMID: 38842059
Recurrence is a rare complication of Group B Streptococcus (GBS) neonatal infections. We conducted a retrospective observational study on GBS neonatal invasive infections in France from 2007 to 2021. 1,527 cases were reported, of which 36 (2.36%) were recurre …
Recurrence is a rare complication of Group B Streptococcus (GBS) neonatal infections. We conducted a retrospective observation …
Performances of two rapid LAMP-based techniques for the intrapartum detection of Group B Streptococcus vaginal colonization.
Charfi R, Guyonnet C, Untrau M, Giacometti G, Paper T, Poyart C, Plainvert C, Tazi A. Charfi R, et al. Among authors: poyart c, plainvert c, tazi a. Ann Clin Microbiol Antimicrob. 2024 Apr 25;23(1):37. doi: 10.1186/s12941-024-00695-2. Ann Clin Microbiol Antimicrob. 2024. PMID: 38664821 Free PMC article.
PURPOSE: Group B Streptococcus (GBS) is the leading cause of invasive infections in newborns. The prevention of GBS neonatal disease relies on the administration of an intrapartum antibiotic prophylaxis to GBS-colonized women. ...False negative results …
PURPOSE: Group B Streptococcus (GBS) is the leading cause of invasive infections in newborns. The prevention of GBS neo …
Specific interaction between Group B Streptococcus CC17 hypervirulent clone and phagocytes.
Bourrel A-S, Picart A, Fernandez J-C, Hays C, Mignon V, Saubaméa B, Poyart C, Fouet A, Tazi A, Guignot J. Bourrel A-S, et al. Among authors: poyart c, tazi a. Infect Immun. 2024 Apr 9;92(4):e0006224. doi: 10.1128/iai.00062-24. Epub 2024 Mar 22. Infect Immun. 2024. PMID: 38514466 Free PMC article.
Streptococcus agalactiae also named Group B Streptococcus (GBS) is the most significant pathogen causing invasive infections, such as bacteremia and meningitis, in neonates. ...Macrophages are a permissive niche for intracellular bacteria of all GBS cl
Streptococcus agalactiae also named Group B Streptococcus (GBS) is the most significant pathogen causing invasive infec
Outbreak of group B Streptococcus in a neonatal care unit confirmed by whole-genome sequencing.
Delettre N, Billion E, Guyonnet C, Jarreau PH, Patkaï J, Tazi A. Delettre N, et al. Among authors: tazi a. Acta Paediatr. 2024 May;113(5):947-954. doi: 10.1111/apa.17095. Epub 2024 Jan 6. Acta Paediatr. 2024. PMID: 38183311
AIM: Clusters of group B Streptococcus (GBS) infections in neonatal intensive care units (NICU) are poorly documented. We aimed to assess GBS cross-transmission during an outbreak of GBS sepsis. METHODS: The study was carried out between October and No …
AIM: Clusters of group B Streptococcus (GBS) infections in neonatal intensive care units (NICU) are poorly documented. We aime …
Acyl-AcpB, a FabT corepressor in Streptococcus pyogenes.
Lambert C, d'Orfani A, Gaillard M, Zhang Q, Gloux K, Poyart C, Fouet A. Lambert C, et al. Among authors: poyart c. J Bacteriol. 2023 Oct 26;205(10):e0027423. doi: 10.1128/jb.00274-23. Epub 2023 Oct 9. J Bacteriol. 2023. PMID: 37811985 Free PMC article.
The role of acyl-AcpB as FabT corepressor is controversial. Streptococcus pyogenes, which causes a wide variety of diseases ranging from mild non-invasive to severe invasive infections, possesses AcpB. ...Streptococci control the expression of the FASII genes via a transcr …
The role of acyl-AcpB as FabT corepressor is controversial. Streptococcus pyogenes, which causes a wide variety of diseases ranging f …
159 results