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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
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1954 2
1955 2
1956 1
1957 1
1959 5
1960 6
1961 2
1962 1
1963 2
1964 1
1965 1
1966 1
1967 3
1968 1
1970 1
1973 1
1976 1
1984 1
1986 3
1989 1
1990 1
1991 1
1992 4
1994 3
1995 4
1996 4
1997 2
1998 3
1999 7
2000 2
2001 5
2002 4
2003 2
2004 4
2005 5
2006 12
2007 14
2008 6
2009 3
2010 12
2011 10
2012 10
2013 13
2014 14
2015 18
2016 12
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2019 24
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Page 1
Horse Chestnut.
[No authors listed] [No authors listed] 2018 Mar 30. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2018 Mar 30. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643542 Free Books & Documents. Review.
Horse chestnut is an herb prepared from the leaves or seeds of the Horse chestnut tree (Aesculus hippocastanum), and is used primarily for complications of venous insufficiency including varicose veins, ankle swelling, and leg cramps. ...
Horse chestnut is an herb prepared from the leaves or seeds of the Horse chestnut tree (Aesculus hippocastanum), and is used p …
Escin: a review of its anti-edematous, anti-inflammatory, and venotonic properties.
Gallelli L. Gallelli L. Drug Des Devel Ther. 2019 Sep 27;13:3425-3437. doi: 10.2147/DDDT.S207720. eCollection 2019. Drug Des Devel Ther. 2019. PMID: 31631970 Free PMC article. Review.
This review discusses historical and recent pharmacological and clinical data on the anti-edematous, anti-inflammatory, and venotonic properties of escin (Reparil()). Escin, the active component of Aesculus hippocastanum, or horse chestnut, is available as orally ab …
This review discusses historical and recent pharmacological and clinical data on the anti-edematous, anti-inflammatory, and venotonic proper …
Esculin inhibits hepatic stellate cell activation and CCl4-induced liver fibrosis by activating the Nrf2/GPX4 signaling pathway.
Xu S, Chen Y, Miao J, Li Y, Liu J, Zhang J, Liang J, Chen S, Hou S. Xu S, et al. Phytomedicine. 2024 Jun;128:155465. doi: 10.1016/j.phymed.2024.155465. Epub 2024 Feb 17. Phytomedicine. 2024. PMID: 38471319
Esculin, a prominent constituent found in the Fraxinus rhynchophylla. (bark), Aesculus hippocastanum. (bark), and Cichorium intybus. (herb), has been shown to possess significant anti-inflammatory, antioxidant, and antibacterial properties. ...
Esculin, a prominent constituent found in the Fraxinus rhynchophylla. (bark), Aesculus hippocastanum. (bark), and Cichorium in …
Phytochemical, ethanomedicinal and pharmacological applications of escin from Aesculus hippocastanum L. towards future medicine.
Idris S, Mishra A, Khushtar M. Idris S, et al. J Basic Clin Physiol Pharmacol. 2020 Jul 10;31(5):/j/jbcpp.2020.31.issue-5/jbcpp-2019-0115/jbcpp-2019-0115.xml. doi: 10.1515/jbcpp-2019-0115. J Basic Clin Physiol Pharmacol. 2020. PMID: 32649293 Free article. Review.
Medicinal plants are used from ancient times for treatment of various ailments. Aesculus hippocastanum (Horse chestnut), is the popular and most valuable tree native to the South East Europe. ...We collected the pharmacological applications of Aesculus hip
Medicinal plants are used from ancient times for treatment of various ailments. Aesculus hippocastanum (Horse chestnut), is th …
Escin avoids hemorrhagic transformation in ischemic stroke by protecting BBB through the AMPK/Cav-1/MMP-9 pathway.
Sun X, Liu Z, Zhou L, Ma R, Zhang X, Wang T, Fu F, Wang Y. Sun X, et al. Phytomedicine. 2023 Nov;120:155071. doi: 10.1016/j.phymed.2023.155071. Epub 2023 Sep 9. Phytomedicine. 2023. PMID: 37716034
The main strategy for combating HT is to keep the blood-brain barrier (BBB) stable. Escin is the active ingredient of Aesculus hippocastanum and a natural mixture of triterpene saponins, and may play a part in mitigation of HT. ...
The main strategy for combating HT is to keep the blood-brain barrier (BBB) stable. Escin is the active ingredient of Aesculus hip
β-Escin: An Updated Review of Its Analysis, Pharmacology, Pharmacokinetics, and Toxicity.
Wang Y, Han X, Wan X, Niu F, Zhou C. Wang Y, et al. Am J Chin Med. 2023;51(8):2095-2120. doi: 10.1142/S0192415X23500908. Epub 2023 Oct 20. Am J Chin Med. 2023. PMID: 37865870 Review.
[Formula: see text]-Escin is an oleanane-type pentacyclic triterpenoid saponin extracted from the seeds of Aesculus hippocastanum (AH), which is more widely distributed. [Formula: see text]-Escin sodium has been approved by the American FDA for clinical usage. ...
[Formula: see text]-Escin is an oleanane-type pentacyclic triterpenoid saponin extracted from the seeds of Aesculus hippocastanum
Somatic Embryogenesis in Horse Chestnut (Aesculus hippocastanum L.).
Capuana M. Capuana M. Methods Mol Biol. 2016;1359:431-8. doi: 10.1007/978-1-4939-3061-6_23. Methods Mol Biol. 2016. PMID: 26619878
Embryogenic cultures of horse chestnut (Aesculus hippocastanum L.) can be obtained from different organs and tissues. We describe here the induction from stamen filaments and the procedures applied for the successive phases of somatic embryo development and maturati …
Embryogenic cultures of horse chestnut (Aesculus hippocastanum L.) can be obtained from different organs and tissues. We descr …
Molecular targets and anti-cancer potential of escin.
Cheong DHJ, Arfuso F, Sethi G, Wang L, Hui KM, Kumar AP, Tran T. Cheong DHJ, et al. Cancer Lett. 2018 May 28;422:1-8. doi: 10.1016/j.canlet.2018.02.027. Epub 2018 Feb 21. Cancer Lett. 2018. PMID: 29474858 Review.
Escin is a mixture of triterpenoid saponins extracted from the horse chestnut tree, Aesculus hippocastanum. Its potent anti-inflammatory and anti-odematous properties makes it a choice of therapy against chronic venous insufficiency and odema. ...
Escin is a mixture of triterpenoid saponins extracted from the horse chestnut tree, Aesculus hippocastanum. Its potent anti-in …
293 results