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Page 1
Recommendations for enterovirus diagnostics and characterisation within and beyond Europe.
Harvala H, Broberg E, Benschop K, Berginc N, Ladhani S, Susi P, Christiansen C, McKenna J, Allen D, Makiello P, McAllister G, Carmen M, Zakikhany K, Dyrdak R, Nielsen X, Madsen T, Paul J, Moore C, von Eije K, Piralla A, Carlier M, Vanoverschelde L, Poelman R, Anton A, López-Labrador FX, Pellegrinelli L, Keeren K, Maier M, Cassidy H, Derdas S, Savolainen-Kopra C, Diedrich S, Nordbø S, Buesa J, Bailly JL, Baldanti F, MacAdam A, Mirand A, Dudman S, Schuffenecker I, Kadambari S, Neyts J, Griffiths MJ, Richter J, Margaretto C, Govind S, Morley U, Adams O, Krokstad S, Dean J, Pons-Salort M, Prochazka B, Cabrerizo M, Majumdar M, Nebbia G, Wiewel M, Cottrell S, Coyle P, Martin J, Moore C, Midgley S, Horby P, Wolthers K, Simmonds P, Niesters H, Fischer TK. Harvala H, et al. J Clin Virol. 2018 Apr;101:11-17. doi: 10.1016/j.jcv.2018.01.008. Epub 2018 Feb 6. J Clin Virol. 2018. PMID: 29414181 Free article. Review.
Sequencing of the VP1 capsid protein gene is recommended for EV typing; EV typing cannot be based on the 5'NCR sequences due to frequent recombination events and should not rely on virus isolation. Effective and standardized laboratory diagnostics and characterisation of c …
Sequencing of the VP1 capsid protein gene is recommended for EV typing; EV typing cannot be based on the 5'NCR sequences due to frequent rec …
Respiratory Viruses in Wastewater Compared with Clinical Samples, Leuven, Belgium.
Rector A, Bloemen M, Thijssen M, Pussig B, Beuselinck K, Van Ranst M, Wollants E. Rector A, et al. Emerg Infect Dis. 2024 Jan;30(1):141-145. doi: 10.3201/eid3001.231011. Emerg Infect Dis. 2024. PMID: 38147067 Free PMC article.
Comparison with the number of positive clinical samples demonstrated that wastewater data reflected circulation levels of typical seasonal respiratory viruses, such as influenza, respiratory syncytial virus, and enterovirus D68....
Comparison with the number of positive clinical samples demonstrated that wastewater data reflected circulation levels of typical seasonal r …
Infectious Myelopathies.
Grill MF. Grill MF. Continuum (Minneap Minn). 2018 Apr;24(2, Spinal Cord Disorders):441-473. doi: 10.1212/CON.0000000000000597. Continuum (Minneap Minn). 2018. PMID: 29613895 Review.
RECENT FINDINGS: Some microorganisms exhibit neurotropism for the spinal cord (eg, enteroviruses such as poliovirus and flaviviruses such as West Nile virus), while others are more protean in neurologic manifestations (eg, herpesviruses such as varicella-zoster virus
RECENT FINDINGS: Some microorganisms exhibit neurotropism for the spinal cord (eg, enteroviruses such as poliovirus and flaviviruses such as …
Receptor-Binding Assays of Enterovirus D68.
Imamura T, Okamoto M, Oshitani H. Imamura T, et al. Methods Mol Biol. 2020;2132:629-639. doi: 10.1007/978-1-0716-0430-4_54. Methods Mol Biol. 2020. PMID: 32306362
Enterovirus 68 Infection--Association with Asthma.
Moss RB. Moss RB. J Allergy Clin Immunol Pract. 2016 Mar-Apr;4(2):226-8. doi: 10.1016/j.jaip.2015.12.013. Epub 2016 Feb 1. J Allergy Clin Immunol Pract. 2016. PMID: 26843407 Review.
A previously sporadic virus called enterovirus 68 (EV-D68) appears to have been associated with asthma-like illness with a predisposition for asthmatics after an outbreak that occurred in North America in 2014. ...
A previously sporadic virus called enterovirus 68 (EV-D68) appears to have been associated with asthma-like illness with a predisposi …
Doxycycline inhibits neurotropic enterovirus proliferation in vitro.
Chi F, Liu X, Li J, Guo M, Zhang Z, Zhou H, Carr MJ, Li Y, Shi W. Chi F, et al. Virus Res. 2024 Jul;345:199388. doi: 10.1016/j.virusres.2024.199388. Epub 2024 May 16. Virus Res. 2024. PMID: 38714218 Free PMC article.
Further investigations indicated that the drug primarily acted at the post-entry stage of virus infection in vitro, with inhibitory effects reaching up to 89 % for EV-A71 when administered two hours post-infection. ...
Further investigations indicated that the drug primarily acted at the post-entry stage of virus infection in vitro, with inhibitory e …
Caspase-3 inhibitor inhibits enterovirus D68 production.
Huo W, Yu J, Liu C, Wu T, Wang Y, Meng X, Song F, Zhang S, Su Y, Liu Y, Liu J, Yu X, Hua S. Huo W, et al. J Microbiol. 2020 Sep;58(9):812-820. doi: 10.1007/s12275-020-0241-y. Epub 2020 Sep 1. J Microbiol. 2020. PMID: 32870487 Free PMC article.
EVD68 infection therefore activates caspase-3 for virus production. This knowledge provides a potential direction for the prevention and treatment of disease related to EVD68....
EVD68 infection therefore activates caspase-3 for virus production. This knowledge provides a potential direction for the prevention …
Seroepidemiology of enterovirus D68 infection in China.
Xiang Z, Li L, Ren L, Guo L, Xie Z, Liu C, Li T, Luo M, Paranhos-Baccalà G, Xu W, Wang J. Xiang Z, et al. Emerg Microbes Infect. 2017 May 10;6(5):e32. doi: 10.1038/emi.2017.14. Emerg Microbes Infect. 2017. PMID: 28487560 Free PMC article.
Human enterovirus 68 (EV-D68) is a rarely reported virus that has been linked to respiratory disease. In recent years, reports about EV-D68 infection have markedly increased worldwide. ...
Human enterovirus 68 (EV-D68) is a rarely reported virus that has been linked to respiratory disease. In recent years, reports about …
A self-amplifying RNA vaccine prevents enterovirus D68 infection and disease in preclinical models.
Warner NL, Archer J, Park S, Singh G, McFadden KM, Kimura T, Nicholes K, Simpson A, Kaelber JT, Hawman DW, Feldmann H, Khandhar AP, Berglund P, Vogt MR, Erasmus JH. Warner NL, et al. Sci Transl Med. 2024 Aug 7;16(759):eadi1625. doi: 10.1126/scitranslmed.adi1625. Epub 2024 Aug 7. Sci Transl Med. 2024. PMID: 39110777
Recently, the National Institutes of Allergy and Infectious Diseases identified nine virus families of concern, eight enveloped virus families and one nonenveloped virus family, for which vaccine generation is a priority. ...
Recently, the National Institutes of Allergy and Infectious Diseases identified nine virus families of concern, eight enveloped vi
Some assembly required: a single-RNA vaccine against enterovirus-D68.
Pollack N, Jackson WT. Pollack N, et al. Trends Pharmacol Sci. 2024 Dec;45(12):1089-1091. doi: 10.1016/j.tips.2024.10.010. Epub 2024 Nov 11. Trends Pharmacol Sci. 2024. PMID: 39532602
A single-RNA-based vaccine against enterovirus-D68, a respiratory virus and causative agent of severe paralytic disease in children, by the Erasmus group shows great promise in generating broadly cross-neutralizing antibodies in mice and macaque models of infection....
A single-RNA-based vaccine against enterovirus-D68, a respiratory virus and causative agent of severe paralytic disease in children, …
210 results