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Page 1
Structural basis of Q-dependent antitermination.
Yin Z, Kaelber JT, Ebright RH. Yin Z, et al. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18384-18390. doi: 10.1073/pnas.1909801116. Epub 2019 Aug 27. Proc Natl Acad Sci U S A. 2019. PMID: 31455742 Free PMC article.
Here, we report high-resolution structures of 4 states on the pathway of antitermination by Q from bacteriophage 21 (Q21): Q21, the Q21-QBE complex, the Q21-loading complex, and the Q21-loaded complex. ...
Here, we report high-resolution structures of 4 states on the pathway of antitermination by Q from bacteriophage 21 (Q21): Q21 …
Lambdoid phages as elements of bacterial genomes (integrase/phage21/Escherichia coli K-12/icd gene).
Campbell A, Schneider SJ, Song B. Campbell A, et al. Genetica. 1992;86(1-3):259-67. doi: 10.1007/BF00133724. Genetica. 1992. PMID: 1468648 Review.
Insertion sites are not located randomly on the E. coli chromosome but are restricted to one segment of the map; also, most prophages are oriented in the same direction along the chromosome. Lambdoid phage 21 inserts within the isocitrate dehydrogenase gene a …
Insertion sites are not located randomly on the E. coli chromosome but are restricted to one segment of the map; also, most prophages are or …
Genetic dissection of T4 lysis.
Moussa SH, Lawler JL, Young R. Moussa SH, et al. J Bacteriol. 2014 Jun;196(12):2201-9. doi: 10.1128/JB.01548-14. Epub 2014 Apr 4. J Bacteriol. 2014. PMID: 24706740 Free PMC article.
This holin topology is different from those of the well-studied holins S105 (3 TMDs; N(out)-C(in)) of the coliphage lambda and S68 (2 TMDs; N(in)-C(in)) of the lambdoid phage 21. Here, we used random mutagenesis to construct a library of lysis-defective allel …
This holin topology is different from those of the well-studied holins S105 (3 TMDs; N(out)-C(in)) of the coliphage lambda and S68 (2 TMDs; …
Essential interaction between lambdoid phage 21 terminase and the Escherichia coli integrative host factor.
Feiss M, Frackman S, Sippy J. Feiss M, et al. J Mol Biol. 1985 May 25;183(2):239-46. doi: 10.1016/0022-2836(85)90216-5. J Mol Biol. 1985. PMID: 2989543
Lambdoid phage 21 requires the Escherichia coli integrative host factor (IHF) for growth. lambda-21 hybrids that have 21 DNA packaging specificity also require IHF. ...
Lambdoid phage 21 requires the Escherichia coli integrative host factor (IHF) for growth. lambda-21 hybrids that have 2
Visualization of pinholin lesions in vivo.
Pang T, Fleming TC, Pogliano K, Young R. Pang T, et al. Proc Natl Acad Sci U S A. 2013 May 28;110(22):E2054-63. doi: 10.1073/pnas.1222283110. Epub 2013 May 13. Proc Natl Acad Sci U S A. 2013. PMID: 23671069 Free PMC article.
Lambdoid phage 21 uses a pinholin-signal anchor release endolysin strategy to effect temporally regulated host lysis. ...
Lambdoid phage 21 uses a pinholin-signal anchor release endolysin strategy to effect temporally regulated host lysis. .
DNA Packaging Specificity in the λ-Like Phages: Gifsy-1.
Feiss M, Sippy JA. Feiss M, et al. Mol Microbiol. 2024 Oct;122(4):491-503. doi: 10.1111/mmi.15306. Epub 2024 Sep 5. Mol Microbiol. 2024. PMID: 39233649
N15 is also shown to package Gifsy-1 DNA. Phage 21 fails to package lambda, N15, and Gifsy-1-specific DNAs; the efficiencies are 0.01%, 0.01%, and 1%, respectively. ...A model is proposed to explain the 100-fold difference in packaging efficiency between lambda and …
N15 is also shown to package Gifsy-1 DNA. Phage 21 fails to package lambda, N15, and Gifsy-1-specific DNAs; the efficiencies a …
A functional domain of bacteriophage lambda terminase for prohead binding.
Frackman S, Siegele DA, Feiss M. Frackman S, et al. J Mol Biol. 1984 Dec 5;180(2):283-300. doi: 10.1016/s0022-2836(84)80005-4. J Mol Biol. 1984. PMID: 6096564
The other known role for terminase in packaging is the production of staggered nicks in the DNA thereby generating the cohesive ends. Lambdoid phage 21 has cohesive ends identical to those of lambda. The head genes of lambda and 21 show partial sequence homol …
The other known role for terminase in packaging is the production of staggered nicks in the DNA thereby generating the cohesive ends. Lam
The pinholin of lambdoid phage 21: control of lysis by membrane depolarization.
Park T, Struck DK, Dankenbring CA, Young R. Park T, et al. J Bacteriol. 2007 Dec;189(24):9135-9. doi: 10.1128/JB.00847-07. Epub 2007 Sep 7. J Bacteriol. 2007. PMID: 17827300 Free PMC article.
The phage 21 holin, S(21), forms small membrane holes that depolarize the membrane and is designated as a pinholin, as opposed to large-hole-forming holins, like S(lambda). ...
The phage 21 holin, S(21), forms small membrane holes that depolarize the membrane and is designated as a pinholin, as opposed …
Bacteriophage lambda DNA packaging: scanning for the terminal cohesive end site during packaging.
Feiss M, Widner W. Feiss M, et al. Proc Natl Acad Sci U S A. 1982 Jun;79(11):3498-502. doi: 10.1073/pnas.79.11.3498. Proc Natl Acad Sci U S A. 1982. PMID: 6285351 Free PMC article.
Bacteriophage lambda packages the DNA of the related phage 21 poorly [Hohn, B. (1975) J. Mol. Biol. 98, 93--106]. To understand the nature of the packaging defect, the interaction of the cohesive end site (cos) specific for phage 21 (cos phi 21) with p …
Bacteriophage lambda packages the DNA of the related phage 21 poorly [Hohn, B. (1975) J. Mol. Biol. 98, 93--106]. To understan …
53 results