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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1986 1
1987 1
1988 4
1989 19
1990 9
1991 8
1992 12
1993 17
1994 14
1995 18
1996 17
1997 18
1998 19
1999 12
2000 14
2001 14
2002 7
2003 14
2004 14
2005 24
2006 18
2007 22
2008 12
2009 16
2010 21
2011 27
2012 22
2013 42
2014 57
2015 95
2016 74
2017 91
2018 85
2019 109
2020 133
2021 155
2022 161
2023 185
2024 205
2025 258
2026 51

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1,889 results

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Page 1
Implications of sleep disturbance and inflammation for Alzheimer's disease dementia.
Irwin MR, Vitiello MV. Irwin MR, et al. Lancet Neurol. 2019 Mar;18(3):296-306. doi: 10.1016/S1474-4422(18)30450-2. Epub 2019 Jan 17. Lancet Neurol. 2019. PMID: 30661858 Review.
Accumulating evidence shows that sleep disturbance contributes to cognitive decline and might also increase the risk of Alzheimer's disease dementia by increasing beta-amyloid burden. That sleep disturbance would be a candidate risk factor for Alzheimer
Accumulating evidence shows that sleep disturbance contributes to cognitive decline and might also increase the risk of Alzheimer' …
Glymphatic dysfunction in Alzheimer's disease: A critical appraisal.
Keil SA, Jansson D, Braun M, Iliff JJ. Keil SA, et al. Science. 2025 Jul 10;389(6756):eadv8269. doi: 10.1126/science.adv8269. Epub 2025 Jul 10. Science. 2025. PMID: 40638744 Review.
Thirteen years after the initial publication defining the glymphatic system, we critically reappraise the role of its dysfunction in Alzheimer's disease (AD). Our understanding of glymphatic function and its involvement in the pathogenesis of AD derives prima …
Thirteen years after the initial publication defining the glymphatic system, we critically reappraise the role of its dysfunction in Alzh
Hypertension and Alzheimer's disease pathology at autopsy: A systematic review.
Abdulrahman H, van Dalen JW, den Brok M, Latimer CS, Larson EB, Richard E. Abdulrahman H, et al. Alzheimers Dement. 2022 Nov;18(11):2308-2326. doi: 10.1002/alz.12707. Epub 2022 Jun 27. Alzheimers Dement. 2022. PMID: 35758526 Free PMC article.
Hypertension is an important risk factor for Alzheimer's disease (AD) and all-cause dementia. The mechanisms underlying this association are unclear. ...
Hypertension is an important risk factor for Alzheimer's disease (AD) and all-cause dementia. The mechanisms underlying …
The power of genetic diversity in genome-wide association studies of lipids.
Graham SE, Clarke SL, Wu KH, Kanoni S, Zajac GJM, Ramdas S, Surakka I, Ntalla I, Vedantam S, Winkler TW, Locke AE, Marouli E, Hwang MY, Han S, Narita A, Choudhury A, Bentley AR, Ekoru K, Verma A, Trivedi B, Martin HC, Hunt KA, Hui Q, Klarin D, Zhu X, Thorleifsson G, Helgadottir A, Gudbjartsson DF, Holm H, Olafsson I, Akiyama M, Sakaue S, Terao C, Kanai M, Zhou W, Brumpton BM, Rasheed H, Ruotsalainen SE, Havulinna AS, Veturi Y, Feng Q, Rosenthal EA, Lingren T, Pacheco JA, Pendergrass SA, Haessler J, Giulianini F, Bradford Y, Miller JE, Campbell A, Lin K, Millwood IY, Hindy G, Rasheed A, Faul JD, Zhao W, Weir DR, Turman C, Huang H, Graff M, Mahajan A, Brown MR, Zhang W, Yu K, Schmidt EM, Pandit A, Gustafsson S, Yin X, Luan J, Zhao JH, Matsuda F, Jang HM, Yoon K, Medina-Gomez C, Pitsillides A, Hottenga JJ, Willemsen G, Wood AR, Ji Y, Gao Z, Haworth S, Mitchell RE, Chai JF, Aadahl M, Yao J, Manichaikul A, Warren HR, Ramirez J, Bork-Jensen J, Kårhus LL, Goel A, Sabater-Lleal M, Noordam R, Sidore C, Fiorillo E, McDaid AF, Marques-Vidal P, Wielscher M, Trompet S, Sattar N, Møllehave LT, Thuesen BH, Munz M, Zeng L, Huang J, Yang B, Poveda A, Kurbasic A, Lamina C, Forer L, Scholz M, Galesl… See abstract for full author list ➔ Graham SE, et al. Nature. 2021 Dec;600(7890):675-679. doi: 10.1038/s41586-021-04064-3. Epub 2021 Dec 9. Nature. 2021. PMID: 34887591 Free PMC article.
Mediterranean and Western diet effects on Alzheimer's disease biomarkers, cerebral perfusion, and cognition in mid-life: A randomized trial.
Hoscheidt S, Sanderlin AH, Baker LD, Jung Y, Lockhart S, Kellar D, Whitlow CT, Hanson AJ, Friedman S, Register T, Leverenz JB, Craft S. Hoscheidt S, et al. Alzheimers Dement. 2022 Mar;18(3):457-468. doi: 10.1002/alz.12421. Epub 2021 Jul 26. Alzheimers Dement. 2022. PMID: 34310044 Free PMC article. Clinical Trial.
INTRODUCTION: Mid-life dietary patterns are associated with Alzheimer's disease (AD) risk, although few controlled trials have been conducted. METHODS: Eighty-seven participants (age range: 45 to 65) with normal cognition (NC, n = 56) or mild cognitive impair …
INTRODUCTION: Mid-life dietary patterns are associated with Alzheimer's disease (AD) risk, although few controlled tria …
A catalog of genetic loci associated with kidney function from analyses of a million individuals.
Wuttke M, Li Y, Li M, Sieber KB, Feitosa MF, Gorski M, Tin A, Wang L, Chu AY, Hoppmann A, Kirsten H, Giri A, Chai JF, Sveinbjornsson G, Tayo BO, Nutile T, Fuchsberger C, Marten J, Cocca M, Ghasemi S, Xu Y, Horn K, Noce D, van der Most PJ, Sedaghat S, Yu Z, Akiyama M, Afaq S, Ahluwalia TS, Almgren P, Amin N, Ärnlöv J, Bakker SJL, Bansal N, Baptista D, Bergmann S, Biggs ML, Biino G, Boehnke M, Boerwinkle E, Boissel M, Bottinger EP, Boutin TS, Brenner H, Brumat M, Burkhardt R, Butterworth AS, Campana E, Campbell A, Campbell H, Canouil M, Carroll RJ, Catamo E, Chambers JC, Chee ML, Chee ML, Chen X, Cheng CY, Cheng Y, Christensen K, Cifkova R, Ciullo M, Concas MP, Cook JP, Coresh J, Corre T, Sala CF, Cusi D, Danesh J, Daw EW, de Borst MH, De Grandi A, de Mutsert R, de Vries APJ, Degenhardt F, Delgado G, Demirkan A, Di Angelantonio E, Dittrich K, Divers J, Dorajoo R, Eckardt KU, Ehret G, Elliott P, Endlich K, Evans MK, Felix JF, Foo VHX, Franco OH, Franke A, Freedman BI, Freitag-Wolf S, Friedlander Y, Froguel P, Gansevoort RT, Gao H, Gasparini P, Gaziano JM, Giedraitis V, Gieger C, Girotto G, Giulianini F, Gögele M, Gordon SD, Gudbjartsson DF, Gudnason V, Haller T, Hamet P, Harris TB, H… See abstract for full author list ➔ Wuttke M, et al. Nat Genet. 2019 Jun;51(6):957-972. doi: 10.1038/s41588-019-0407-x. Epub 2019 May 31. Nat Genet. 2019. PMID: 31152163 Free PMC article.
An integrated view of the relationships between amyloid, tau, and inflammatory pathophysiology in Alzheimer's disease.
Arnsten AFT, Del Tredici K, Barthélemy NR, Gabitto M, van Dyck CH, Lein E, Braak H, Datta D. Arnsten AFT, et al. Alzheimers Dement. 2025 Aug;21(8):e70404. doi: 10.1002/alz.70404. Alzheimers Dement. 2025. PMID: 40767321 Free PMC article. Review.
Alzheimer's disease (AD) research is a large and burgeoning field, where varied methodological approaches are providing multifaceted, but sometimes contradictory, views on the etiology and progression of pathology. ...
Alzheimer's disease (AD) research is a large and burgeoning field, where varied methodological approaches are providing
The Alzheimer's Disease Gene SORL1 Regulates Lysosome Function in Human Microglia.
Mishra S, Morshed N, Sidhu SB, Kinoshita C, Stevens B, Jayadev S, Young JE. Mishra S, et al. Glia. 2025 Jul;73(7):1329-1348. doi: 10.1002/glia.70009. Epub 2025 Apr 4. Glia. 2025. PMID: 40183375 Free PMC article.
Loss of function variants in SORL1 are causative for Alzheimer's disease (AD) and decreased expression of SORLA has been repeatedly observed in human AD brains. ...
Loss of function variants in SORL1 are causative for Alzheimer's disease (AD) and decreased expression of SORLA has bee …
HDL Proteome and Alzheimer's Disease: Evidence of a Link.
Marsillach J, Adorni MP, Zimetti F, Papotti B, Zuliani G, Cervellati C. Marsillach J, et al. Antioxidants (Basel). 2020 Dec 3;9(12):1224. doi: 10.3390/antiox9121224. Antioxidants (Basel). 2020. PMID: 33287338 Free PMC article. Review.
Several lines of epidemiological evidence link increased levels of high-density lipoprotein-cholesterol (HDL-C) with lower risk of Alzheimer's disease (AD). This observed relationship might reflect the beneficial effects of HDL on the cardiovascular system, l …
Several lines of epidemiological evidence link increased levels of high-density lipoprotein-cholesterol (HDL-C) with lower risk of Alzhei
1,889 results