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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1840 1
1843 1
1845 1
1847 1
1849 1
1858 1
1865 1
1866 3
1869 1
1870 1
1871 1
1878 1
1881 1
1883 2
1884 2
1885 2
1886 1
1887 1
1889 1
1890 1
1891 1
1893 1
1894 3
1896 1
1904 2
1917 1
1919 1
1924 1
1928 1
1931 1
1932 2
1934 1
1936 1
1939 1
1940 4
1941 1
1942 2
1944 1
1945 9
1946 16
1947 6
1948 13
1949 2
1950 7
1951 9
1952 6
1953 11
1954 7
1955 5
1956 2
1957 1
1958 4
1959 7
1960 6
1961 8
1962 10
1963 12
1964 17
1965 16
1966 12
1967 59
1968 114
1969 168
1970 236
1971 348
1972 425
1973 492
1974 461
1975 369
1976 411
1977 325
1978 340
1979 267
1980 273
1981 263
1982 198
1983 193
1984 212
1985 221
1986 229
1987 222
1988 195
1989 206
1990 208
1991 272
1992 224
1993 269
1994 295
1995 389
1996 365
1997 466
1998 511
1999 475
2000 620
2001 689
2002 759
2003 785
2004 1005
2005 1230
2006 1303
2007 1489
2008 1645
2009 1583
2010 1750
2011 1888
2012 2171
2013 2254
2014 2474
2015 2603
2016 2871
2017 2965
2018 3470
2019 3987
2020 4932
2021 2941
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49,547 results
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Page 1
Pharmacology of Medical Cannabis.
Amin MR, Ali DW. Amin MR, et al. Adv Exp Med Biol. 2019;1162:151-165. doi: 10.1007/978-3-030-21737-2_8. Adv Exp Med Biol. 2019. PMID: 31332738 Review.
The predominant psychotropic component is delta(9)-tetrahydrocannabinol (delta(9)-THC), while the major non-psychoactive ingredient is cannabidiol (CBD). ...However, there is a lack of well-controlled, double blind, randomized clinical trials to provide clarity on t …
The predominant psychotropic component is delta(9)-tetrahydrocannabinol (delta(9)-THC), while the major non-psychoactive ingredient i …
Cannabis, from plant to pill.
Grof CPL. Grof CPL. Br J Clin Pharmacol. 2018 Nov;84(11):2463-2467. doi: 10.1111/bcp.13618. Epub 2018 May 24. Br J Clin Pharmacol. 2018. PMID: 29701252 Free PMC article. Review.
The therapeutic application of cannabis is attracting substantial public and clinical interest. The cannabis plant has been described as a veritable 'treasure trove', producing more than 100 different cannabinoids, although the focus to date has been on the psychoac …
The therapeutic application of cannabis is attracting substantial public and clinical interest. The cannabis plant has been de …
The endocannabinoid system and the brain.
Mechoulam R, Parker LA. Mechoulam R, et al. Annu Rev Psychol. 2013;64:21-47. doi: 10.1146/annurev-psych-113011-143739. Epub 2012 Jul 12. Annu Rev Psychol. 2013. PMID: 22804774 Review.
The psychoactive constituent in cannabis, delta(9)-tetrahydrocannabinol (THC), was isolated in the mid-1960s, but the cannabinoid receptors, CB1 and CB2, and the major endogenous cannabinoids (anandamide and 2-arachidonoyl glycerol) were identified only 20 to 25 yea …
The psychoactive constituent in cannabis, delta(9)-tetrahydrocannabinol (THC), was isolated in the mid-1960s, but the cannabin …
Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects.
Russo EB. Russo EB. Br J Pharmacol. 2011 Aug;163(7):1344-64. doi: 10.1111/j.1476-5381.2011.01238.x. Br J Pharmacol. 2011. PMID: 21749363 Free PMC article. Review.
Tetrahydrocannabinol (THC) has been the primary focus of cannabis research since 1964, when Raphael Mechoulam isolated and synthesized it. More recently, the synergistic contributions of cannabidiol to cannabis pharmacology and analgesia have been scientifica …
Tetrahydrocannabinol (THC) has been the primary focus of cannabis research since 1964, when Raphael Mechoulam isolated and syn …
The endocannabinoid system.
Kilaru A, Chapman KD. Kilaru A, et al. Essays Biochem. 2020 Sep 23;64(3):485-499. doi: 10.1042/EBC20190086. Essays Biochem. 2020. PMID: 32648908 Review.
Thirty years ago, the discovery of a cannabinoid (CB) receptor that interacts with the psychoactive compound in Cannabis led to the identification of anandamide, an endogenous receptor ligand or endocannabinoid. ...Specifically, in humans, the release of endocann
Thirty years ago, the discovery of a cannabinoid (CB) receptor that interacts with the psychoactive compound in Cannabis led to the i …
General and oral health implications of cannabis use.
Cho CM, Hirsch R, Johnstone S. Cho CM, et al. Aust Dent J. 2005 Jun;50(2):70-4. doi: 10.1111/j.1834-7819.2005.tb00343.x. Aust Dent J. 2005. PMID: 16050084 Free article. Review.
There are three main forms of cannabis: marijuana, hash and hash oil, all of which contain the main psychoactive constituent delta-9-tetrahydrocannabinol (THC). ...THC from cannabis enters the bloodstream and exerts its effects on the body via interact …
There are three main forms of cannabis: marijuana, hash and hash oil, all of which contain the main psychoactive constituent delta-9- …
Cannabinoids, interoception, and anxiety.
Andrade AK, Renda B, Murray JE. Andrade AK, et al. Pharmacol Biochem Behav. 2019 May;180:60-73. doi: 10.1016/j.pbb.2019.03.006. Epub 2019 Mar 25. Pharmacol Biochem Behav. 2019. PMID: 30922834 Review.
Cannabis use, though relatively safe compared to other drugs of abuse, has been associated with greater risk of mental health disorders, possibly via its primary psychoactive constituent, delta-9-tetrahydrocannabinol (THC). In this review, we discuss endocannabin
Cannabis use, though relatively safe compared to other drugs of abuse, has been associated with greater risk of mental health disorde
Endocannabinoid System Components: Overview and Tissue Distribution.
Joshi N, Onaivi ES. Joshi N, et al. Adv Exp Med Biol. 2019;1162:1-12. doi: 10.1007/978-3-030-21737-2_1. Adv Exp Med Biol. 2019. PMID: 31332731 Review.
Evidence based research and remarkable biotechnological advances demonstrate that phytocannabinoids and endocannabinoid (eCBs) acting on cannabinoid receptors (CBRs) regulate various aspects of human physiological, behavioral, immunological and metabolic functions. The dis …
Evidence based research and remarkable biotechnological advances demonstrate that phytocannabinoids and endocannabinoid (eCBs) acting …
Cannabis and Cardiovascular Disease.
Ghosh M, Naderi S. Ghosh M, et al. Curr Atheroscler Rep. 2019 Apr 12;21(6):21. doi: 10.1007/s11883-019-0783-9. Curr Atheroscler Rep. 2019. PMID: 30980200 Review.
PURPOSE OF REVIEW: The use of recreational drugs has increased globally, with the most commonly used recreational drug being cannabis. As of 2019, 10 states and the District of Columbia have legalized cannabis for recreational use, with more states potentially joini …
PURPOSE OF REVIEW: The use of recreational drugs has increased globally, with the most commonly used recreational drug being cannabis
Cannabis.
Grayson M. Grayson M. Nature. 2015 Sep 24;525(7570):S1. doi: 10.1038/525S1a. Nature. 2015. PMID: 26398730 No abstract available.
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