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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1977 3
1979 2
1981 2
1983 1
1986 1
1987 1
1988 1
1989 2
1991 5
1992 4
1993 2
1994 2
1995 5
1996 6
1997 12
1998 15
1999 23
2000 18
2001 16
2002 19
2003 39
2004 41
2005 40
2006 48
2007 51
2008 85
2009 80
2010 104
2011 104
2012 106
2013 115
2014 111
2015 120
2016 148
2017 134
2018 145
2019 158
2020 130
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1,682 results
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Page 1
Posttranslational control of HuR function.
Grammatikakis I, Abdelmohsen K, Gorospe M. Grammatikakis I, et al. Wiley Interdiscip Rev RNA. 2017 Jan;8(1):10.1002/wrna.1372. doi: 10.1002/wrna.1372. Epub 2016 Jun 16. Wiley Interdiscip Rev RNA. 2017. PMID: 27307117 Free PMC article. Review.
The RNA-binding protein HuR (human antigen R) associates with numerous transcripts, coding and noncoding, and controls their splicing, localization, stability, and translation. ...In turn, HuR influences processes such as cancer and infla …
The RNA-binding protein HuR (human antigen R) associates with numerous transcripts, coding and noncoding, …
Activation of ferritinophagy is required for the RNA-binding protein ELAVL1/HuR to regulate ferroptosis in hepatic stellate cells.
Zhang Z, Yao Z, Wang L, Ding H, Shao J, Chen A, Zhang F, Zheng S. Zhang Z, et al. Autophagy. 2018;14(12):2083-2103. doi: 10.1080/15548627.2018.1503146. Epub 2018 Aug 21. Autophagy. 2018. PMID: 30081711 Free PMC article.
In this study, we report that the RNA-binding protein ELAVL1/HuR plays a crucial role in regulating ferroptosis in liver fibrosis. ...Abbreviations: ACTA2/alpha-SMA: actin, alpha 2, smooth muscle, aorta; ACTB/beta-actin: actin beta; ARE: AU-rich element; ATG: …
In this study, we report that the RNA-binding protein ELAVL1/HuR plays a crucial role in regulating ferroptosis in live …
WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1.
Chen Y, Peng C, Chen J, Chen D, Yang B, He B, Hu W, Zhang Y, Liu H, Dai L, Xie H, Zhou L, Wu J, Zheng S. Chen Y, et al. Mol Cancer. 2019 Aug 22;18(1):127. doi: 10.1186/s12943-019-1053-8. Mol Cancer. 2019. PMID: 31438961 Free PMC article.
However, as the key component of m6A methylation, Wilms tumor 1-associated protein (WTAP) has not been well studied in HCC. Here we investigated the biological role and underlying mechanism of WTAP in liver cancer. ...Furthermore, ETS proto-oncogene 1 (ETS1) …
However, as the key component of m6A methylation, Wilms tumor 1-associated protein (WTAP) has not been well studied in HCC. He …
The Jun/miR-22/HuR regulatory axis contributes to tumourigenesis in colorectal cancer.
Liu Y, Chen X, Cheng R, Yang F, Yu M, Wang C, Cui S, Hong Y, Liang H, Liu M, Zhao C, Ding M, Sun W, Liu Z, Sun F, Zhang C, Zhou Z, Jiang X, Chen X. Liu Y, et al. Mol Cancer. 2018 Jan 19;17(1):11. doi: 10.1186/s12943-017-0751-3. Mol Cancer. 2018. PMID: 29351796 Free PMC article.
Hu antigen R (HuR), which is highly upregulated in CRC, functions as a pivotal oncogene to promote CRC progression. However, the underlying cause of its dysregulation is poorly understood. METHODS: In CRC tissue sample pairs, HuR protein
Hu antigen R (HuR), which is highly upregulated in CRC, functions as a pivotal oncogene to promote CRC progressi
Hu antigen R (HuR) heterogeneous expression quantification as a prognostic marker of melanoma.
Liaudet N, Fernandez M, Fontao L, Kaya G, Merat R. Liaudet N, et al. J Cutan Pathol. 2018 May;45(5):333-336. doi: 10.1111/cup.13119. Epub 2018 Feb 23. J Cutan Pathol. 2018. PMID: 29393978
The mainly nuclear RNA-binding protein human antigen R (HuR) regulates the protein expression of thousands of mRNAs, its own heterogeneous expression could therefore reflect tumor heterogeneity and plasticity. ...METHODS: We conducted an …
The mainly nuclear RNA-binding protein human antigen R (HuR) regulates the protein expression of t …
Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA.
Wang M, Mao C, Ouyang L, Liu Y, Lai W, Liu N, Shi Y, Chen L, Xiao D, Yu F, Wang X, Zhou H, Cao Y, Liu S, Yan Q, Tao Y, Zhang B. Wang M, et al. Cell Death Differ. 2019 Nov;26(11):2329-2343. doi: 10.1038/s41418-019-0304-y. Epub 2019 Feb 20. Cell Death Differ. 2019. PMID: 30787392 Free PMC article.
LINC00336 bound RNA-binding protein ELAVL1 (ELAV-like RNA-binding protein 1) using nucleotides 1901-2107 of LINC00336 and the RRM interaction domain and key amino acids (aa) of ELAVL1 (aa 101-213), inhibiting ferroptosis. Moreover, …
LINC00336 bound RNA-binding protein ELAVL1 (ELAV-like RNA-binding protein 1) using nucleotides 190 …
Circ-HuR suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation.
Yang F, Hu A, Li D, Wang J, Guo Y, Liu Y, Li H, Chen Y, Wang X, Huang K, Zheng L, Tong Q. Yang F, et al. Mol Cancer. 2019 Nov 13;18(1):158. doi: 10.1186/s12943-019-1094-z. Mol Cancer. 2019. PMID: 31718709 Free PMC article.
Our previous study has identified that circAGO2 drives gastric cancer progression through activating human antigen R (HuR), a protein stabilizing AU-rich element-containing mRNAs. ...Mechanistically, circ-HuR interacted with CCHC-type zin …
Our previous study has identified that circAGO2 drives gastric cancer progression through activating human antigen R ( …
Alternative 3' UTRs act as scaffolds to regulate membrane protein localization.
Berkovits BD, Mayr C. Berkovits BD, et al. Nature. 2015 Jun 18;522(7556):363-7. doi: 10.1038/nature14321. Epub 2015 Apr 20. Nature. 2015. PMID: 25896326 Free PMC article.
About half of human genes use alternative cleavage and polyadenylation (ApA) to generate messenger RNA transcripts that differ in the length of their 3' untranslated regions (3' UTRs) while producing the same protein. ...CD47 protein localization occurs post- …
About half of human genes use alternative cleavage and polyadenylation (ApA) to generate messenger RNA transcripts that differ in the …
Targeting exosome-associated human antigen R attenuates fibrosis and inflammation in diabetic heart.
Govindappa PK, Patil M, Garikipati VNS, Verma SK, Saheera S, Narasimhan G, Zhu W, Kishore R, Zhang J, Krishnamurthy P. Govindappa PK, et al. FASEB J. 2020 Feb;34(2):2238-2251. doi: 10.1096/fj.201901995R. Epub 2019 Dec 16. FASEB J. 2020. PMID: 31907992
RNA-binding proteins like human antigen R (HuR) are key regulators in post-transcriptional control of gene expression in several pathophysiological conditions. ...Human failing hearts show higher HuR levels. Diabetic milieu activat …
RNA-binding proteins like human antigen R (HuR) are key regulators in post-transcriptional control of gen …
UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis.
Wang X, Liu R, Zhu W, Chu H, Yu H, Wei P, Wu X, Zhu H, Gao H, Liang J, Li G, Yang W. Wang X, et al. Nature. 2019 Jul;571(7763):127-131. doi: 10.1038/s41586-019-1340-y. Epub 2019 Jun 26. Nature. 2019. PMID: 31243371
Cancer metastasis is the primary cause of morbidity and mortality, and accounts for up to 95% of cancer-related deaths(1). Cancer cells often reprogram their metabolism to efficiently support cell proliferation and survival(2,3). ...Here we show that, after activation of E …
Cancer metastasis is the primary cause of morbidity and mortality, and accounts for up to 95% of cancer-related deaths(1). Cancer cel …
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