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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 1
2004 1
2006 1
2007 2
2008 3
2009 3
2010 3
2011 4
2012 4
2013 2
2014 7
2015 9
2016 6
2017 6
2018 9
2019 12
2020 8
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71 results
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METTL3-mediated N6-methyladenosine modification is critical for epithelial-mesenchymal transition and metastasis of gastric cancer.
Yue B, Song C, Yang L, Cui R, Cheng X, Zhang Z, Zhao G. Yue B, et al. Mol Cancer. 2019 Oct 13;18(1):142. doi: 10.1186/s12943-019-1065-4. Mol Cancer. 2019. PMID: 31607270 Free PMC article.
METHODS: qRT-PCR and immunohistochemistry were used to evaluate the expression of methyltransferase-like 3 (METTL3) in gastric cancer (GC). ...The m6A modification of ZMYM1 mRNA by METTL3 enhanced its stability relying on the "reader" protein HuR (also known as E
METHODS: qRT-PCR and immunohistochemistry were used to evaluate the expression of methyltransferase-like 3 (METTL3) in gastric cancer …
WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1.
Chen Y, Peng C, Chen J, Chen D, Yang B, He B, Hu W, Zhang Y, Liu H, Dai L, Xie H, Zhou L, Wu J, Zheng S. Chen Y, et al. Mol Cancer. 2019 Aug 22;18(1):127. doi: 10.1186/s12943-019-1053-8. Mol Cancer. 2019. PMID: 31438961 Free PMC article.
BACKGROUND: N6-methyladenosine (m6A) methylation, a well-known modification with new epigenetic functions, has been reported to participate in the tumorigenesis of hepatocellular carcinoma (HCC), providing novel insights into the molecular pathogenesis of this disease. ... …
BACKGROUND: N6-methyladenosine (m6A) methylation, a well-known modification with new epigenetic functions, has been reported to participate …
Circ-HuR suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation.
Yang F, Hu A, Li D, Wang J, Guo Y, Liu Y, Li H, Chen Y, Wang X, Huang K, Zheng L, Tong Q. Yang F, et al. Mol Cancer. 2019 Nov 13;18(1):158. doi: 10.1186/s12943-019-1094-z. Mol Cancer. 2019. PMID: 31718709 Free PMC article.
BACKGROUND: Circular RNAs (circRNAs), a subclass of non-coding RNAs, play essential roles in tumorigenesis and aggressiveness. Our previous study has identified that circAGO2 drives gastric cancer progression through activating human antigen R (HuR
BACKGROUND: Circular RNAs (circRNAs), a subclass of non-coding RNAs, play essential roles in tumorigenesis and aggressiveness. Our pr …
Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA.
Wang M, Mao C, Ouyang L, Liu Y, Lai W, Liu N, Shi Y, Chen L, Xiao D, Yu F, Wang X, Zhou H, Cao Y, Liu S, Yan Q, Tao Y, Zhang B. Wang M, et al. Cell Death Differ. 2019 Nov;26(11):2329-2343. doi: 10.1038/s41418-019-0304-y. Epub 2019 Feb 20. Cell Death Differ. 2019. PMID: 30787392 Free PMC article.
LINC00336 bound RNA-binding protein ELAVL1 (ELAV-like RNA-binding protein 1) using nucleotides 1901-2107 of LINC00336 and the RRM interaction domain and key amino acids (aa) of ELAVL1 (aa 101-213), inhibiting ferroptosis. ...These data show that the network o …
LINC00336 bound RNA-binding protein ELAVL1 (ELAV-like RNA-binding protein 1) using nucleotides 1901-2107 of LINC00336 and the …
Circular RNA circAGO2 drives cancer progression through facilitating HuR-repressed functions of AGO2-miRNA complexes.
Chen Y, Yang F, Fang E, Xiao W, Mei H, Li H, Li D, Song H, Wang J, Hong M, Wang X, Huang K, Zheng L, Tong Q. Chen Y, et al. Cell Death Differ. 2019 Jul;26(7):1346-1364. doi: 10.1038/s41418-018-0220-6. Epub 2018 Oct 19. Cell Death Differ. 2019. PMID: 30341421 Free PMC article.
Mechanistic studies reveal that circAGO2 physically interacts with human antigen R (HuR) protein to facilitate its activation and enrichment on the 3'-untranslated region of target genes, resulting in reduction of AGO2 binding and repression of AGO2/mi …
Mechanistic studies reveal that circAGO2 physically interacts with human antigen R (HuR) protein to facilitate i …
ALKBH5 inhibited autophagy of epithelial ovarian cancer through miR-7 and BCL-2.
Zhu H, Gan X, Jiang X, Diao S, Wu H, Hu J. Zhu H, et al. J Exp Clin Cancer Res. 2019 Apr 15;38(1):163. doi: 10.1186/s13046-019-1159-2. J Exp Clin Cancer Res. 2019. PMID: 30987661 Free PMC article.
In the present study, we investigated the expression and function of ALKBH5 in epithelial ovarian cancer with respect to its potential role in the tumorigenesis of the disease as well as an early diagnostic marker. ...Mechanical study revealed that ALKBH5 physically intera …
In the present study, we investigated the expression and function of ALKBH5 in epithelial ovarian cancer with respect to its potential role …
The Ribonucleic Complex HuR-MALAT1 Represses CD133 Expression and Suppresses Epithelial-Mesenchymal Transition in Breast Cancer.
Latorre E, Carelli S, Raimondi I, D'Agostino V, Castiglioni I, Zucal C, Moro G, Luciani A, Ghilardi G, Monti E, Inga A, Di Giulio AM, Gorio A, Provenzani A. Latorre E, et al. Cancer Res. 2016 May 1;76(9):2626-36. doi: 10.1158/0008-5472.CAN-15-2018. Epub 2016 Apr 20. Cancer Res. 2016. PMID: 27197265 Free article.
In this study, we show that a ribonucleoprotein complex including the long noncoding RNA MALAT1 and the RNA-binding protein HuR (ELAVL1) binds the CD133 promoter region to regulate its expression. In luminal nonmetastatic MCF-7 breast cancer cells, HuR silenc …
In this study, we show that a ribonucleoprotein complex including the long noncoding RNA MALAT1 and the RNA-binding protein HuR (E
Progress on the relationship between miR-125 family and tumorigenesis.
Yin H, Sun Y, Wang X, Park J, Zhang Y, Li M, Yin J, Liu Q, Wei M. Yin H, et al. Exp Cell Res. 2015 Dec 10;339(2):252-60. doi: 10.1016/j.yexcr.2015.09.015. Epub 2015 Sep 25. Exp Cell Res. 2015. PMID: 26407906 Review.
miRNA-125 family, which is a highly conserved miRNA family throughout evolution, is consist of miRNA-125a-3p, miRNA-125a-5p, miRNA-125b-1 and miRNA-125b-2.The aberrant expression of miR-125 familyis tightly related to tumorigenesis and tumor development. The downstream tar …
miRNA-125 family, which is a highly conserved miRNA family throughout evolution, is consist of miRNA-125a-3p, miRNA-125a-5p, miRNA-125b-1 an …
Role of MYC-regulated long noncoding RNAs in cell cycle regulation and tumorigenesis.
Kim T, Jeon YJ, Cui R, Lee JH, Peng Y, Kim SH, Tili E, Alder H, Croce CM. Kim T, et al. J Natl Cancer Inst. 2015 Feb 6;107(4):dju505. doi: 10.1093/jnci/dju505. Print 2015 Apr. J Natl Cancer Inst. 2015. PMID: 25663692 Free PMC article.
The transcription factor MYC is known to regulate lncRNAs and has been implicated in cancer cell proliferation and tumorigenesis. ...RNA binding proteins including HuR and hnRNPK are involved in the function of MYCLos by interacting with MYCLo-1 and MYCLo-2, respect …
The transcription factor MYC is known to regulate lncRNAs and has been implicated in cancer cell proliferation and tumorigenesis. ... …
The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro.
Kaur K, Wu X, Fields JK, Johnson DK, Lan L, Pratt M, Somoza AD, Wang CCC, Karanicolas J, Oakley BR, Xu L, De Guzman RN. Kaur K, et al. PLoS One. 2017 Apr 17;12(4):e0175471. doi: 10.1371/journal.pone.0175471. eCollection 2017. PLoS One. 2017. PMID: 28414767 Free PMC article.
The RNA-binding protein Hu antigen R (HuR) binds to AU-rich elements (ARE) in the 3'-untranslated region (UTR) of target mRNAs. The HuR-ARE interactions stabilize many oncogenic mRNAs that play important roles in tumorigenesis. Thus, small molec …
The RNA-binding protein Hu antigen R (HuR) binds to AU-rich elements (ARE) in the 3'-untranslated region (UTR) of targe …
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